Patents by Inventor Adeline Sivignon

Adeline Sivignon has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • GLYCOSIDE INHIBITORS OF YEAST
    Publication number: 20240148778
    Abstract: A composition of yeast polysaccharides including ?(1,6)-glucans, preferably also mannans and ?-glucans. The yeast polysaccharides are extracted from yeast cell wall fragments. Typically, the ?-glucans are ?(1,6)-glucans. Also, a method for obtaining such a composition, including at least one step of fractionating a composition of yeast cell walls and extracting an insoluble fraction, and at least one step of extracting a soluble fraction from the insoluble fraction obtained in step a). Further, a composition with a human or veterinary therapeutic objective, for the treatment of gastrointestinal pathologies associated with pathogenic microorganisms, as well as to its non-therapeutic use for improving intestinal comfort.
    Type: Application
    Filed: March 15, 2022
    Publication date: May 9, 2024
    Applicants: LESAFFRE ET COMPAGNIE, UNIVERSITÉ CLERMONT AUVERGNE, UNIVERSITE DE LILLE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS
    Inventors: Nathalie BALLET, Pascal VANDEKERCKOVE, Yann GUERARDEL, Shin-Yi YU, Adeline SIVIGNON, Nicolas BARNICH
  • Orally available compounds, a process for preparing the same and their uses as anti-adhesive drugs for treating induced inflammatory bowel diseases such as crohn's disease
    Patent number: 10632135
    Abstract: Orally available compounds, a process for preparing the same and their uses as anti-adhesive drugs for treating E. coli induced inflammatory bowel diseases such as crohn's disease.
    Type: Grant
    Filed: August 22, 2019
    Date of Patent: April 28, 2020
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE D'AUVERGNE, UNIVERSITE DES SCIENCES ET TECHNOLOGIES DE LILLE 1, UNIVERSITE DE NANTES, INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
    Inventors: Julie Bouckaert, Sebastien Gouin, Adeline Sivignon, Arlette Darfeuille-Michaud, Rostyslav Bilyy, Dimitri Alvarez-Dorta, Nao Yamakawa, Tetiana Dumych
  • Mannose derivatives useful for treating pathologies associated with adherent
    Patent number: 10543223
    Abstract: The present invention relates to mannose derivatives of formula (I): wherein R1 represents H, CO—(C1-C6)-alkyl or CO-alkylaryl, Y represents a single bond, CH2, O, NR3, S, A represents O, NH or S, X represents H and X? represents OH or X and X? taken together with the carbon atom bearing them form a CO group, R2 represents H, a linear or branched (C1-C6)-alkyl or CF3, R3 represents H, a C1-C6 alkyl, a CO—(C1-C6)-alkyl, CF3 or COCF3, and R is as described in claim 1.
    Type: Grant
    Filed: August 5, 2016
    Date of Patent: January 28, 2020
    Assignees: ENTEROME, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE CLERMONT AUVERGNE, UNIVERSITE DE NANTES
    Inventors: Sebastien Gouin, Thibault Chalopin, Julie Bouckaert, Nicolas Barnich, Adeline Sivignon, Dimitri Alexander Alvarez-Dorta, Francois Bellamy
  • ORALLY AVAILABLE COMPOUNDS, A PROCESS FOR PREPARING THE SAME AND THEIR USES AS ANTI-ADHESIVE DRUGS FOR TREATING E. COLI INDUCED INFLAMMATORY BOWEL DISEASES SUCH AS CROHN'S DISEASE
    Publication number: 20190374559
    Abstract: Orally available compounds, a process for preparing the same and their uses as anti-adhesive drugs for treating E. coli induced inflammatory bowel diseases such as crohn's disease.
    Type: Application
    Filed: August 22, 2019
    Publication date: December 12, 2019
    Inventors: Julie BOUCKAERT, Sebastien GOUIN, Adeline SIVIGNON, Arlette DARFEUILLE-MICHAUD, Rostyslav BILYY, Dimitri ALVAREZ-DORTA, Nao YAMAKAWA, Tetiana DUMYCH
  • Orally available compounds, a process for preparing the same and their uses as anti-adhesive drugs for treating induced inflammatory bowel diseases such as crohn's disease
    Patent number: 10485811
    Abstract: Orally available compounds, a process for preparing the same and their uses as anti-adhesive drugs for treating E. coli induced inflammatory bowel diseases such as crohn's disease.
    Type: Grant
    Filed: January 23, 2015
    Date of Patent: November 26, 2019
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE D'AUVERGNE, UNIVERSITE DES SCIENCES ET TECHNOLOGIES DE LILLE 1, UNIVERSITE DE NANTES, INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE)
    Inventors: Julie Bouckaert, Sebastien Gouin, Adeline Sivignon, Arlette Darfeuille-Michaud, Rostyslav Bilyy, Dimitri Alvarez-Dorta, Nao Yamakawa, Tetiana Dumych
  • Multimeric mannosides, a process for preparing the same and their uses as a drug
    Patent number: 10273313
    Abstract: The present invention relates to multimeric mannosides, a process for preparing the same and their uses in medicine for treating Escherichia coli infections.
    Type: Grant
    Filed: July 24, 2013
    Date of Patent: April 30, 2019
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE DE NANTES, UNIVERSITE DE PICARDIE JULES VERNE, UNIVERSITE LILLE 1-SCIENCES ET TECHNOLOGIES, UNIVERSITE D'AUVERGNE
    Inventors: Julie Bouckaert, Sebastien Gouin, David Deniaud, Rostyslav Bilyy, Tetiana Dumych, Adeline Sivignon, Arlette Darfeuille-Michaud
  • MANNOSE DERIVATIVES USEFUL FOR TREATING PATHOLOGIES ASSOCIATED WITH ADHERENT E. COLI
    Publication number: 20180235991
    Abstract: The present invention relates to mannose derivatives of formula (I): wherein R1 represents H, CO—(C1-C6)-alkyl or CO-alkylaryl, Y represents a single bond, CH2, O, NR3, S, A represents O, NH or S, X represents H and X? represents OH or X and X? taken together with the carbon atom bearing them form a CO group, R2 represents H, a linear or branched (C1-C6)-alkyl or CF3, R3 represents H, a C1-C6 alkyl, a CO—(C1-C6)-alkyl, CF3 or COCF3, and R is as described in claim 1.
    Type: Application
    Filed: August 5, 2016
    Publication date: August 23, 2018
    Inventors: Sebastien GOUIN, Thibault CHALOPIN, Julie BOUCKAERT, Nicolas BARNICH, Adeline SIVIGNON, Dimitri Alexander ALVAREZ-DORTA, Francois BELLAMY
  • ORALLY AVAILABLE COMPOUNDS, A PROCESS FOR PREPARING THE SAME AND THEIR USES AS ANTI-ADHESIVE DRUGS FOR TREATING E. COLI INDUCED INFLAMMATORY BOWEL DISEASES SUCH AS CROHN'S DISEASE
    Publication number: 20160340445
    Abstract: Orally available compounds, a process for preparing the same and their uses as anti-adhesive drugs for treating E. coli induced inflammatory bowel diseases such as crohn's disease.
    Type: Application
    Filed: January 23, 2015
    Publication date: November 24, 2016
    Inventors: Julie BOUCKAERT, Sebastien GOUIN, Adeline SIVIGNON, Arlette DARFEUILLE-MICHAUD (Deceased), Rostyslav BILYY, Dimitri ALVAREZ-DORTA, Nao YAMAKAWA, Tetiana DUMYCH
  • MULTIMERIC MANNOSIDES, A PROCESS FOR PREPARING THE SAME AND THEIR USES AS A DRUG
    Publication number: 20150210781
    Abstract: The present invention relates to multimeric mannosides, a process for preparing the same and their uses in medicine for treating Escherichia Coli infections.
    Type: Application
    Filed: July 24, 2013
    Publication date: July 30, 2015
    Inventors: Julie Bouckaert, Sebastien Gouin, David Deniaud, Rostyslav Bilyy, Tetiana Dumych, Adeline Sivignon, Arlette Darfeuille-Michaud
  • Probiotic yeast compositions and methods for inflammatory diseases
    Patent number: 8476058
    Abstract: The invention relates to novel yeast strains, to the yeasts resulting from these strains, to a composition containing at least one Saccharomyces cerevisiae yeast and/or derivatives of a yeast having a particular interest as a food additive and/or probiotic and/or functional food and/or neutraceutic and/or functional ingredient and/or cosmeceutical and/or pharmaceutical active agent. The invention also relates to the use of the same in human and/or animal nutrition, or for the treatment or prevention of inflammatory diseases.
    Type: Grant
    Filed: December 12, 2008
    Date of Patent: July 2, 2013
    Assignees: Lesaffre et Compagnie, Universite du Droit et de la Sante Lille 2, Universite d 'Auvergne Clermont 1
    Inventors: Jean-Luc Simon, Georges Pignede, Pascal Vandekerckove, Pierre Desreumaux, Daniel Poulain, Arlette Darfeuille-Michaud, Adeline Sivignon
  • COMPOSITION FOR HUMAN AND/OR ANIMAL NUTRITION, USES THEREOF AND YEASTS
    Publication number: 20100303778
    Abstract: The invention relates to novel yeast strains, to the yeasts resulting from these strains, to a composition containing at least one Saccharomyces cerevisiae yeast and/or derivatives of a yeast having a particular interest as a food additive and/or probiotic and/or functional food and/or neutraceutic and/or functional ingredient and/or cosmeceutical and/or pharmaceutical active agent. The invention also relates to the use of the same in human and/or animal nutrition, or for the treatment or prevention of inflammatory diseases.
    Type: Application
    Filed: December 12, 2008
    Publication date: December 2, 2010
    Inventors: Jean-Luc Simon, Georges Pignede, Pascal Vandekerckove, Daniel Poulain, Pierre Desreumaux, Arlette Darfeuille-Michaud, Adeline Sivignon