Patents by Inventor Adolfo Jose LOPEZ DE MUNAIN ARREGI

Adolfo Jose LOPEZ DE MUNAIN ARREGI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Triazoles for regulating intracellular calcium homeostasis
    Patent number: 11377427
    Abstract: The present invention relates to 1,2,3-triazoles of formula: useful for improving or restoring the intracellular calcium homeostasis and RyR-calstabin binding function in human and animal cells. The present invention also relates to methods for synthesizing said compounds, to pharmaceutical compositions containing them, and to the use thereof for preventing or treating skeletal muscle, heart and nervous system disorders.
    Type: Grant
    Filed: May 23, 2017
    Date of Patent: July 5, 2022
    Assignees: UNIVERSIDAD DEL PAIS VASCO, ADMINISTRACION GENERAL DE LA COMUNIDAD AUTONOMA DE EUSKADI
    Inventors: Ainara Vallejo Illarramendi, Adolfo Jose Lopez De Munain Arregi, Pablo Ferron Celma, Jesus Maria Aizpurua Iparraguirre, Aitziber Irastorza Epelde, Jose Ignacio Miranda Murua, Ivan Toral Ojeda, Garazi Aldanondo Aristizabal
  • TRIAZOLES FOR REGULATING INTRACELLULAR CALCIUM HOMEOSTASIS
    Publication number: 20200317625
    Abstract: The present invention relates to 1,2,3-triazoles of formula: useful for improving or restoring the intracellular calcium homeostasis and RyR-calstabin binding function in human and animal cells. The present invention also relates to methods for synthesizing said compounds, to pharmaceutical compositions containing them, and to the use thereof for preventing or treating skeletal muscle, heart and nervous system disorders.
    Type: Application
    Filed: May 23, 2017
    Publication date: October 8, 2020
    Inventors: Ainara VALLEJO ILLARRAMENDI, Adolfo Jose LOPEZ DE MUNAIN ARREGI, Pablo FERRON CELMA, Jesus Maria AIZPURUA IPARRAGUIRRE, Aitziber IRASTORZA EPELDE, Jose Ignacio MIRANDA MURUA, Ivan TORAL OJEDA, Garazi ALDANONDO ARISTIZABAL
  • METHODS AND COMPOSITIONS FOR THE DIAGNOSIS AND FOR THE TREATMENT OF ADRENOLEUKODYSTROPHY
    Publication number: 20190010535
    Abstract: The present invention is directed to a diagnostic method for adrenoleukodystrophy in a subject based on the determination of the levels of different markers. The invention also provides a method for monitoring the progression of an adrenoleukodystrophy, a method for monitoring the effect of an adrenoleukodystrophy therapy and fingolimod, an analogue, metabolite or derivative thereof, or a pharmaceutically acceptable salt thereof, for use in the treatment and/or prevention of anadrenoleukodystrophy.
    Type: Application
    Filed: July 14, 2016
    Publication date: January 10, 2019
    Inventors: Aurora PUJOL ONOFRE, Manuel PORTERO OTIN, Reinaldo PAMPLONA GRAS, Adolfo Jose LOPEZ DE MUNAIN ARREGI, Mariona JOVE FONT, Stephane FOURCADE