Patents by Inventor Adrian Lees
Adrian Lees has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11992535Abstract: Provided herein are certain compounds and imaging agents useful for detecting a condition or disorder associated with protein aggregation, compositions thereof, and methods of their use.Type: GrantFiled: December 17, 2020Date of Patent: May 28, 2024Assignee: CHDI Foundation, Inc.Inventors: Longbin Liu, Matthew Lee, Celia Dominguez, Peter David Johnson, Christopher John Brown, Sarah Hayes, Adrian Kotey, Matthew Robert Mills, Michael Edward Prime
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Patent number: 11971895Abstract: A determination is made as to whether a data type associated with a received logical table definition associated with a database query within a distributed database system differs from a data type associated with a local logical table definition. A data conversion is performed on data retrieved from a locally-stored physical table referenced by the local logical table definition in response to determining that the data types differ. Local data conversion information is created identifying the data conversion performed on the retrieved data in response to performing the data conversion. At least one of the retrieved data and the converted data with the created local data conversion information is forwarded to at least one of a distributed database node and an application-level module.Type: GrantFiled: July 19, 2019Date of Patent: April 30, 2024Assignee: International Business Machines CorporationInventor: Adrian Lee
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Patent number: 11972307Abstract: Implementations set forth herein relate to an automated assistant that can be invoked while a user is interfacing with a foreground application in order to retrieve data from one or more different applications, and then provide the retrieved data to the foreground application. A user can invoke the automated assistant while operating the foreground application by providing a spoken utterance, and the automated assistant can select one or more other applications to query based on content of the spoken utterance. Application data collected by the automated assistant from the one or more other applications can then be used to provide an input to the foreground application. In this way, the user can bypass switching between applications in the foreground in order to retrieve data that has been generated by other applications.Type: GrantFiled: August 6, 2019Date of Patent: April 30, 2024Assignee: GOOGLE LLCInventors: Bohdan Vlasyuk, Behshad Behzadi, Mario Bertschler, Denis Burakov, Daniel Cotting, Michael Golikov, Lucas Mirelmann, Steve Cheng, Sergey Nazarov, Zaheed Sabur, Jonathan Lee, Lucia Terrenghi, Adrian Zumbrunnen
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Publication number: 20240103970Abstract: In an example, a computing device includes a processor which in a reimaging operation of the computing device, may determine if a backup image to be used in the reimaging operation is available from a memory device connected to a local area network of the computing device. When the backup image is available from the memory device, the processor may acquire the backup image over the local area network. When the backup image is not available from the memory device, the processor may determine if a backup image is available from a wide area network of the computing device.Type: ApplicationFiled: September 23, 2022Publication date: March 28, 2024Inventors: Gaetan Wattiau, Adrian John Baldwin, Stuart Lees
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Publication number: 20240092757Abstract: Provided herein are compounds that activate IRE1/XBP1s, and pharmaceutically acceptable derivatives thereof. Also provided are pharmaceutical compositions containing the compounds and methods of using the compounds for treating a subject having a disease or disorder that may be ameliorated by increasing IRE1/XBP1s activity.Type: ApplicationFiled: November 8, 2023Publication date: March 21, 2024Inventors: Richard F. Labaudiniere, Bradley Dean Tait, Hank Michael James Petrassi, Jeffery W. Kelly, R. Luke Wiseman, Kyunga Lee, Adrian Marco Guerrero
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Patent number: 11933446Abstract: A modular enclosure system and method for repair of one or more leaks in a pipe. The modular enclosure system including a first enclosure portion configured to be disposed in a mated configuration to create a first enclosure around the pipe. Each enclosure includes a first void section configured to enclose a pipe section of the pipe. Sealant grooves extend along enclosure faces of each enclosure to seal the modular enclosure system. Each enclosure includes a sealant control system having a plurality of blocking members and configured to selectively block sealant injected in the sealant grooves. Each of the blocking members are positionable between a blocking position configured to block sealant flow in at least one of the sealant grooves and a non-blocking position.Type: GrantFiled: February 6, 2020Date of Patent: March 19, 2024Assignee: Team Industrial Services, Inc.Inventors: Adrian Garcia, Adam Thistlethwaite, Matthew Guest, Andrew Campbell, Daniel Chalupsky, Mark Lee Swain, Matthew Yasensky
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Publication number: 20230418433Abstract: A computing system for pixel-based automated testing of a navigable simulated environment includes one or more processors configured to execute, in a run-time inference phase, an application testing program. The application testing program includes a machine learning model trained to detect errors in the application under test. A screen image of the simulated environment is processed by an object detection module to determine if a key object is present in the screen image. If a key object is present in the screen image, the application testing program executes an object investigation module to generate investigation inputs to investigate the key object. If a key object is not present in the screen image, the application testing program executes an environment exploration module to generate an environment exploration action to be provided to the application under test as simulated user input.Type: ApplicationFiled: July 17, 2023Publication date: December 28, 2023Applicant: Microsoft Technology Licensing, LLCInventors: Guoqing LIU, Li ZHAO, Tao QIN, Adrian Lee BROWN, James Eugene BISCHOFF, JR., Tieyan LIU
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Patent number: 11662513Abstract: Methods based on growth pattern models are utilized to determine patterns of reflective dots in optical combiners or other components for augmented reality (AR), head mounted displays (HMD) and/or head up display (HUD) applications. Optical combiners including the reflective dots arranged in the grown patterns are provided.Type: GrantFiled: January 9, 2020Date of Patent: May 30, 2023Assignee: META PLATFORMS TECHNOLOGIES, LLCInventor: Adrian Lee Stannard
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Patent number: 11548939Abstract: Disclosed herein are methods of treating a subject with an estrogen receptor-positive (ER+) breast cancer comprising obtaining a sample of the breast cancer from the subject; determining a level of E-cadherin in the sample is reduced compared to a control; and administering a therapeutically effective amount of an IGF1R pathway inhibitor and an endocrine therapeutic. Also disclosed herein are methods to treat a cancer in a subject comprising administering a therapeutically effective amount of an IGF1R pathway inhibitor and an E-cadherin inhibitor. Also disclosed are methods to predict the likelihood a subject with a breast cancer will respond therapeutically to a treatment comprising administering an IGF1R pathway inhibitor, the method comprising obtaining a sample of the cancer from the subject; and determining a level of E-cadherin in the sample.Type: GrantFiled: February 26, 2019Date of Patent: January 10, 2023Assignee: University Of Pittsburgh-Of The Commonwealth System Of Higher EducationInventors: Adrian Lee, Alison Nagle, Steffi Oesterreich
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Patent number: 11144677Abstract: A fully digital integrated circuit apparatus (200) and method (300) are provided for generating a test mode enable signal with a digital non-resettable state retention storage circuit (210) connected to store an authentication control pattern for authorizing test mode access to a secure circuit, a digital safety interlock gate circuit (220) connected to store a safety interlock gate setting that may be accessed independently from a test mode enable signal, and combinatorial logic circuitry (205) for generating the test mode enable signal only when the interlock safety gate setting is set to a first value and the digital non-resettable state retention storage circuit stores the authentication control code.Type: GrantFiled: August 8, 2019Date of Patent: October 12, 2021Assignee: NXP USA, Inc.Inventors: Stefan Doll, Thomas Henry Luedeke, Nikila Krishnamoorthy, Hubert Glenn Carson, Jr., Anurag Jindal, Hilario Manuel Garza, Kamel Musa Khalaf, Joel Ray Knight, Adrian Lee Carleton
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Publication number: 20210042447Abstract: A fully digital integrated circuit apparatus (200) and method (300) are provided for generating a test mode enable signal with a digital non-resettable state retention storage circuit (210) connected to store an authentication control pattern for authorizing test mode access to a secure circuit, a digital safety interlock gate circuit (220) connected to store a safety interlock gate setting that may be accessed independently from a test mode enable signal, and combinatorial logic circuitry (205) for generating the test mode enable signal only when the interlock safety gate setting is set to a first value and the digital non-resettable state retention storage circuit stores the authentication control code.Type: ApplicationFiled: August 8, 2019Publication date: February 11, 2021Applicant: NXP USA, Inc.Inventors: Stefan Doll, Thomas Henry Luedeke, Nikila Krishnamoorthy, Hubert Glenn Carson, JR., Anurag Jindal, Hilario Manuel Garza, Kamel Musa Khalaf, Joel Ray Knight, Adrian Lee Carleton
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Patent number: 10757547Abstract: A registration is received from an application framework. The registration is for the application framework to be notified of an event managed by a service gateway. The event is based on a communication service provided by the service gateway. The service gateway detects the event. The service gateway sends a notification associated with the event to the application framework. The notification associated with the event comprises information associated with the event. For example, the notification may include a caller's name and address. An object is received from the application framework that is associated with the event. The object associated with the event further comprises extension information that is not used by the communication service/service gateway. A message is sent to a communication endpoint and/or an external application that comprises the object. The extension information is used to provide custom services that are not supported by the communication service/service gateway.Type: GrantFiled: November 8, 2017Date of Patent: August 25, 2020Assignee: Avaya Inc.Inventors: Mehmet Balasaygun, Rajeshwari Edamadaka, Adrian Lee, Ruby Agarwal
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Publication number: 20200225400Abstract: Methods based on growth pattern models are utilized to determine patterns of reflective dots in optical combiners or other components for augmented reality (AR), head mounted displays (HMD) and/or head up display (HUD) applications. Optical combiners including the reflective dots arranged in the grown patterns are provided.Type: ApplicationFiled: January 9, 2020Publication date: July 16, 2020Applicant: Daqri, LlcInventor: Adrian Lee Stannard
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Patent number: 10607167Abstract: Systems and methods are shown for routing task objects to multiple agents that involve receiving and storing real-time sensor data for multiple agents, receiving tasks and, for each task, create a task object representing the task and placing the task object in an input buffer. For each task object in the input buffer, utilize the real-time sensor data to identify one or more of the multiple agents as suitable for assignment to the task, apply a routing strategy to the task object to further select one of the multiple agents identified as suitable for assignment of the task object based on sensor data, and route the task object from the input buffer to a workbin corresponding to the selected agent.Type: GrantFiled: October 13, 2015Date of Patent: March 31, 2020Inventors: Herbert Willi Artur Ristock, Adrian Lee-Kwen, David Beilis, Christopher Connolly, Liyuan Qiao, Merijn te Booij, James Kraeutler
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Patent number: 10587449Abstract: A region specific proxy server receives a first request to establish a communication session from a communication device. The first request is based on an address of the region specific proxy server identified by a DNS server. The region specific proxy server generates and sends, to a media control service, a second request to identify a region specific media relay. The second request comprises the address of the region specific proxy server. The proxy server receives, from the media control service, an address of the region specific media relay that is selected based on the address of the region specific proxy server. The proxy server sends the address of the region specific media relay to the communication device. The communication device uses the address of the region specific media relay to establish a media communication session (e.g., a voice media communication session) using the region specific media relay.Type: GrantFiled: July 18, 2017Date of Patent: March 10, 2020Assignee: Avaya Inc.Inventors: Jason G. Tanabe, Mehmet Balasaygun, Adrian Lee, Jing (Jerry) Xie
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Publication number: 20190361893Abstract: A determination is made as to whether a data type associated with a received logical table definition associated with a database query within a distributed database system differs from a data type associated with a local logical table definition. A data conversion is performed on data retrieved from a locally-stored physical table referenced by the local logical table definition in response to determining that the data types differ. Local data conversion information is created identifying the data conversion performed on the retrieved data in response to performing the data conversion. At least one of the retrieved data and the converted data with the created local data conversion information is forwarded to at least one of a distributed database node and an application-level module.Type: ApplicationFiled: July 19, 2019Publication date: November 28, 2019Inventor: Adrian Lee
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Publication number: 20190315847Abstract: Disclosed herein are methods of treating a subject with an estrogen receptor-positive (ER+) breast cancer comprising obtaining a sample of the breast cancer from the subject; determining a level of E-cadherin in the sample is reduced compared to a control; and administering a therapeutically effective amount of an IGF1R pathway inhibitor and an endocrine therapeutic. Also disclosed herein are methods to treat a cancer in a subject comprising administering a therapeutically effective amount of an IGF1R pathway inhibitor and an E-cadherin inhibitor. Also disclosed are methods to predict the likelihood a subject with a breast cancer will respond therapeutically to a treatment comprising administering an IGF1R pathway inhibitor, the method comprising obtaining a sample of the cancer from the subject; and determining a level of E-cadherin in the sample.Type: ApplicationFiled: February 26, 2019Publication date: October 17, 2019Inventors: Adrian Lee, Alison Nagle, Steffi Oesterreich
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Patent number: 10380131Abstract: A determination is made as to whether a data type associated with a received logical table definition associated with a database query within a distributed database system differs from a data type associated with a local logical table definition. A data conversion is performed on data retrieved from a locally-stored physical table referenced by the local logical table definition in response to determining that the data types differ. Local data conversion information is created identifying the data conversion performed on the retrieved data in response to performing the data conversion. At least one of the retrieved data and the converted data with the created local data conversion information is forwarded to at least one of a distributed database node and an application-level module.Type: GrantFiled: August 24, 2012Date of Patent: August 13, 2019Assignee: INTERNATIONAL BUSINESS MACHINES CORPORATIONInventor: Adrian Lee
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Patent number: 10376083Abstract: A storage rack device for storing, shaping, and displaying baseball caps includes a bottom plate, a top plate, and a pair of rods. The rods are coupled to and extend between the bottom plate and the top plate. The rods are opposingly positioned proximate to a lower circumference of the top plate and extend in parallel to the bottom plate. The pair of rods is configured to selectively insert a bill of a cap to couple the cap to the pair of rods so that the bill is selectively positionable in a curved configuration and a flat configuration.Type: GrantFiled: June 19, 2018Date of Patent: August 13, 2019Inventors: Adrian Lee, Patricia Lee
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Publication number: 20190141491Abstract: A registration is received from an application framework. The registration is for the application framework to be notified of an event managed by a service gateway. The event is based on a communication service provided by the service gateway. The service gateway detects the event. The service gateway sends a notification associated with the event to the application framework. The notification associated with the event comprises information associated with the event. For example, the notification may include a caller's name and address. An object is received from the application framework that is associated with the event. The object associated with the event further comprises extension information that is not used by the communication service/service gateway. A message is sent to a communication endpoint and/or an external application that comprises the object. The extension information is used to provide custom services that are not supported by the communication service/service gateway.Type: ApplicationFiled: November 8, 2017Publication date: May 9, 2019Inventors: Mehmet Balasaygun, Rajeshwari Edamadaka, Adrian Lee, Ruby Agarwal