Abstract: MECP2 EXPRESSION CASSETTES. The present invention provides nucleic acid molecules comprising a MeCP2 expression cassette, the expression cassette comprising, in operable linkage from 5? to 3?: a 5? transcriptional control region comprising a promoter capable of driving transcription in neural cells; an open reading frame encoding a MeCP2 protein; translation control signals; a 3? untranslated region (3?UTR) comprising one or more of: (i) a binding site for mir-22; (ii) a binding site for mir-19; (iii) a binding site for miR-132; (iv) a binding site for miR124; and (v) an AU-rich element; and transcriptional termination signals; wherein the MeCP2 expression cassette is not more than about 5 kb in length. The invention further provides viral vectors, especially vectors derived from adeno-associated virus (AAV), for use in therapeutic delivery of such expression cassettes.

Abstract: The present invention provides nucleic acid molecules comprising a MeCP2 expression cassette, the expression cassette comprising, in operable linkage from 5? to 3?: a 5? transcriptional control region comprising a promoter capable of driving transcription in neural cells; an open reading frame encoding a MeCP2 protein; translation control signals; a 3? untranslated region (3?UTR) comprising one or more of: (i) a binding site for mir-22; (ii) a binding site for mir-19; (iii) a binding site for miR-132; (iv) a binding site for miR124; and (v) an AU-rich element; and transcriptional termination signals; wherein the MeCP2 expression cassette is not more than about 5 kb in length. The invention further provides viral vectors, especially vectors derived from adeno-associated virus (AAV), for use in therapeutic delivery of such expression cassettes.

Abstract: A robot system and a method for packaging coils of sheet metal is provided. The method and robot system for coil packaging, having two industrial robots, each robot being provided with a robot arm provides for a solution where the direction of travel along the envelope surface of the coil is inclined relative the rotational axis of the coil, positioning of the roll of wrapping material in three-dimensional along the circumferential edge may be adjusted for each pass and/or where the positioning of the longitudinal axis of the roll or wrapping material is in an inclined angular direction relative the direction of rotation.

Abstract: The invention relates to a thermal-type flow sensor (1) for a flow meter, comprising a main channel part (3b) with a main channel (3) for a medium whose flow is to be determined, a sensor tube (4), having a first tube portion (5), a second, opposite tube portion (8), a sensing portion (11) connecting the first and second tube portions, at least two sensing or heating elements (12) for measuring a temperature differential or a power differential in the sensor tube, a thermally conductive frame element (13) in contact with at least the first tube portion, the second tube portion as well as the main channel part, configured to equalize temperature gradients, wherein thermally conductive frame element (13) is a printed circuit board (PCB) (14).

Abstract: An array of anode assemblies for insertion at a plurality of locations in a gap between a section of a reinforced concrete structure and another solid structure is provided. Each anode assembly comprises an expandable member, an anode attached to the expandable member for protecting a steel reinforcement in the reinforced concrete structure, and an anode connector for interconnecting the array of anode assemblies. During use, each anode assembly of the array of anode assemblies is inserted into the gap, between the section of the reinforced concrete structure and the solid structure, at the plurality of locations. The expandable member of each anode assembly is configured to expand so as to press the anode into contact with a surface of the reinforced concrete structure.

Abstract: A robot tool, a robot system and a method for packaging coils of sheet metal. A robot tool for coil packaging, having two ends, each end being provided with a coupling tool piece configured to interface with a robot arm; a roll holder shaft configured to hold a roll of wrapping material, the holder shaft at one end being rotatably mounted substantially midway between said ends and projecting substantially perpendicular to an axis extending between said ends. A robot system for coil packaging, having two industrial robots, each robot being provided with a robot arm having a coupling robot piece configured to interface with a robot tool; and a robot tool, the robot tool having two ends, each end being provided with a coupling tool piece configured to interface with a said robot arm.

Abstract: A planar optical element (e.g., a camera) is provided comprising a diverter for diverting light from an object into an imaging plane; a planar lens waveguide in the imaging plane, receiving the diverted light and focusing it onto a line; and a sensor line located on the focus line, for forming a one-dimensional image of the object. Many such elements can be applied to a planar substrate at different angles, and the one-dimensional inputs Fourier-analysed to reconstruct the desired two-dimensional image. The elements may be transparent, so that the substrate may be a display screen; eliminating the need to locate a camera to the side of the screen. The elements can cover all or most of the screen, and a subset chosen at any given time to constitute the camera. The system can also be run backwards as a projector, with light-emitting elements instead of sensors.

Abstract: A self-encrypting drive (SED) comprises an SED controller and a nonvolatile storage medium (NVSM) responsive to the SED controller. The SED controller enables the SED to perform operations comprising: (a) receiving an encrypted media encryption key (eMEK) for a client; (b) decrypting the eMEK into an unencrypted media encryption key (MEK); (c) receiving a write request from the client, wherein the write request includes data to be stored and a key tag value associated with the MEK; (d) using the key tag value to select the MEK for the write request; (e) using the MEK for the write request to encrypt the data from the client; and (f) storing the encrypted data in a region of the NVSM allocated to the client. Other embodiments are described and claimed.

Abstract: An ultrasonic flow measurement system (1) comprising a flow tube (11), an ultrasound damping layer (12), an ultrasound transmitter (13) covered by the ultrasound damping layer, and an ultrasound receiver (14) covered by the ultrasound damping layer, characterised in that the ultrasound damping layer comprises: —a first damping portion (121) that is at least partially positioned in between the ultrasound transmitter and the ultrasound receiver as well as—a second damping portion (122) that is at least partially positioned in between the ultrasound transmitter and the ultrasound receiver, wherein the first damping portion and the second damping portion of the ultrasound damping layer are spaced apart from each other by a distance (d) in an axial direction (A) of the flow tube.

Abstract: Certain examples of the present invention relate to a protective cover 100, and method of using the same, for protecting forensic evidence 104 and/or a forensic scene 604?. The cover 100 comprises a covering member 101 for at least partially covering forensic evidence 104 and/or an entry way to a forensic scene 604?, wherein the covering member 101 is configured to be breathable 106 and waterproof 107; a fixing means 102 for affixing the cover 100 to a surface 105 in an affixed condition 100?, wherein the affixing means 102 is provided at each peripheral edge 101a-101d of the covering member 101; and tamper indicating means 103 for indicating tampering of the cover in the affixed condition 100?, wherein the tamper indicating means 103 is provided at each peripheral edge 101a-101d of the covering member 101.

Abstract: An optical device including a first rigid substrate, a flexible holographic optical element, a transparent flexible material having a variable shear transmission property across an in-plane direction of the flexible holographic optical element, and a second rigid substrate, where the flexible holographic optical element and the transparent flexible material are located between the first and second rigid substrates, where the variable shear transmission property of the transparent flexible material transmits variable amounts of a shear force applied to the first or second rigid substrates across the in-plane direction of the flexible holographic optical element.

Abstract: An optical device comprises a pixel array including one or more pixels. Two or more independently controllable electrodes are electrically coupled to each pixel. A common ground reference electrode is electrically coupled to all pixels of the pixel array. Each pixel includes a plurality of liquid crystal molecules. The liquid crystal molecules may be oriented in a first direction based on a first function of voltages applied by the two or more independently controllable electrodes for the pixel, and oriented in a second direction based on a second function of the voltages applied by the two or more independently controllable electrodes for the pixel. In this way, both phase modulation and polarization modulation may be introduced to light illuminating the pixel array.

Abstract: Examples are disclosed that relate to holographic display systems. One example provides a display system comprising a waveguide, a light source configured to introduce light into the waveguide at a controllable light input angle, and a holographic optical element (HOE) configured to outcouple from the waveguide light received from within the waveguide that meets an angular condition. The display system may further comprise a controller configured to control the light input angle and also to control a corrective component optically downstream of the HOE to correct for aberration of the light by the HOE based upon the light input angle.

Abstract: A holographic display system includes a holographic optical element (HOE), which includes a first volume hologram configured to outcouple light to form a first exit pupil upon satisfaction of a first angular condition, and a second volume hologram configured to outcouple light to form a second exit pupil upon satisfaction of a second angular condition. A light source is configured to introduce light into the HOE at any of a range of angles. A light source controller sets a current angle of the light to a first angle that meets the first angular condition, forming the first exit pupil. The light source controller moves the first exit pupil by changing the current angle to a second angle that meets the first angular condition. The light source controller redirects light to form the second exit pupil by setting the current angle to a third angle that meets the second angular condition.

Abstract: An array of anode assemblies for insertion at a plurality of locations in a gap between a section of a reinforced concrete structure and another solid structure is provided. Each anode assembly comprises an expandable member, an anode attached to the expandable member for protecting a steel reinforcement in the reinforced concrete structure, and an anode connector for interconnecting the array of anode assemblies. During use, each anode assembly of the array of anode assemblies is inserted into the gap, between the section of the reinforced concrete structure and the solid structure, at the plurality of locations. The expandable member of each anode assembly is configured to expand so as to press the anode into contact with a surface of the reinforced concrete structure.

Abstract: A self-encrypting drive (SED) comprises an SED controller and a nonvolatile storage medium (NVSM) responsive to the SED controller. The SED controller enables the SED to perform operations comprising: (a) receiving an encrypted media encryption key (eMEK) for a client; (b) decrypting the eMEK into an unencrypted media encryption key (MEK); (c) receiving a write request from the client, wherein the write request includes data to be stored and a key tag value associated with the MEK; (d) using the key tag value to select the MEK for the write request; (e) using the MEK for the write request to encrypt the data from the client; and (f) storing the encrypted data in a region of the NVSM allocated to the client. Other embodiments are described and claimed.

Abstract: An optical device including a first rigid substrate, a flexible holographic optical element, a transparent flexible material having a variable shear transmission property across an in-plane direction of the flexible holographic optical element, and a second rigid substrate, wherein the flexible holographic optical element and the transparent flexible material are located between the first and second rigid substrates, wherein the variable shear transmission property of the transparent flexible material transmits variable amounts of a shear force applied to the first or second rigid substrates across the in-plane direction of the flexible holographic optical element.

Abstract: An optical device comprises a pixel array including one or more pixels. Two or more independently controllable electrodes are electrically coupled to each pixel. A common ground reference electrode is electrically coupled to all pixels of the pixel array. Each pixel includes a plurality of liquid crystal molecules. The liquid crystal molecules may be oriented in a first direction based on a first function of voltages applied by the two or more independently controllable electrodes for the pixel, and oriented in a second direction based on a second function of the voltages applied by the two or more independently controllable electrodes for the pixel. In this way, both phase modulation and polarization modulation may be introduced to light illuminating the pixel array.