Patents by Inventor Adrian Tersteegen

Adrian Tersteegen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted fused imidazoles and pyrazoles and use thereof
    Patent number: 9023849
    Abstract: The present application relates to novel substituted fused imidazoles and pyrazoles, to processes for preparation thereof, to the use thereof, alone or in combinations, for treatment and/or prophylaxis of diseases and to the use thereof producing medicaments for the treatment and/or prophylaxis of diseases, especially for treatment and/or prophylaxis of cardiovascular disorders.
    Type: Grant
    Filed: January 8, 2013
    Date of Patent: May 5, 2015
    Assignee: Bayer Intellectual Property GmbH
    Inventors: Markus Follmann, Johannes-Peter Stasch, Gorden Redlich, Nils Griebenow, Dieter Lang, Frank Wunder, Holger Paulsen, Walter Hübsch, Alexandros Vakalopoulos, Adrian Tersteegen
  • Substituted annellated pyrimidines and use thereof
    Publication number: 20150105374
    Abstract: The present application relates to novel substituted annellated pyrimidines, methods for production thereof, use thereof alone or in combinations for treating and/or preventing diseases and use thereof for the production of medicinal products for treating and/or preventing diseases, in particular for treating and/or preventing cardiovascular diseases.
    Type: Application
    Filed: September 19, 2014
    Publication date: April 16, 2015
    Inventors: Markus FOLLMANN, Johannes-Peter STASCH, Gorden REDLICH, Nils GRIEBENOW, Dieter LANG, Frank WUNDER, Walter HÜBSCH, Niels LINDNER, Alexandros VAKALOPOULOS, Adrian TERSTEEGEN
  • SUBSTITUTED ANNULATED PYRIMIDINES AND TRIAZINES, AND USE THEREOF
    Publication number: 20140357637
    Abstract: The present application relates to novel substituted fused pyrimidines and triazines, to processes for their preparation, to their use alone or in combinations for the treatment and/or prophylaxis of diseases, and to their use for producing medicaments for the treatment and/or prophylaxis of diseases, in particular for the treatment and/or prophylaxis of cardiovascular disorders.
    Type: Application
    Filed: January 10, 2013
    Publication date: December 4, 2014
    Inventors: Markus Follmann, Johannes-Peter Stasch, Gorden Redlich, Nils Griebenow, Dieter Lang, Frank Wunder, Walter Hübsch, Alexandros Vakalopoulos, Adrian Tersteegen
  • Substituted annellated pyrimidines and use thereof
    Patent number: 8859569
    Abstract: The present application relates to novel substituted annellated pyrimidines, methods for production thereof, use thereof alone or in combinations for treating and/or preventing diseases and use thereof for the production of medicinal products for treating and/or preventing diseases, in particular for treating and/or preventing cardiovascular diseases.
    Type: Grant
    Filed: August 30, 2012
    Date of Patent: October 14, 2014
    Assignees: Bayer Pharma Aktiengesellschaft, Bayer Intellectual Property GmbH
    Inventors: Markus Follmann, Johannes-Peter Stasch, Gorden Redlich, Nils Griebenow, Dieter Lang, Frank Wunder, Walter Hübsch, Niels Lindner, Alexandros Vakalopoulos, Adrian Tersteegen
  • Substituted oxazolidinones and their use
    Patent number: 8846934
    Abstract: The invention relates to novel substituted oxazolidinones, to processes for their preparation, to their use for the treatment and/or prophylaxis of diseases and their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular of thromboembolic disorders.
    Type: Grant
    Filed: February 19, 2013
    Date of Patent: September 30, 2014
    Assignee: Bayer Intellectual Property GmbH
    Inventors: Swen Allerheiligen, Marcus Bauser, Dirk Heimbach, Stefan Heitmeier, Mark Gnoth, Christoph Gerdes, Georges Degenfeld, Susanne Röhrig, Ulrich Rester, Elke Dittrich-Wengenroth, Uwe Saatman, Adrian Tersteegen
  • Trifluoromethyl-substituted fused pyrimidines and their use
    Publication number: 20140249168
    Abstract: The present application relates to novel trifluoromethyl-substituted fused pyrimidines, to processes for their preparation, to their use alone or in combinations for the treatment and/or prophylaxis of diseases, and to their use for producing medicaments for the treatment and/or prophylaxis of diseases, in particular for the treatment and/or prophylaxis of cardiovascular disorders.
    Type: Application
    Filed: February 28, 2014
    Publication date: September 4, 2014
    Applicant: BAYER PHARMA AKTIENGESELLSCHAFT
    Inventors: Markus FOLLMANN, Johannes-Peter STASCH, Gorden REDLICH, Dieter LANG, Alexandros VAKALOPOULOS, Frank WUNDER, Adrian TERSTEEGEN
  • 6-cyclylmethyl-and 6-alkylmethyl-substituted pyrazolepyrimidines
    Patent number: 8822479
    Abstract: The invention relates to 6-cyclylmethyl- and 6-alkylmethyl-substituted pyrazolopyrimidines, process for their preparation, and their use for producing medicaments for improving learning and/or memory. The 6-cyclylmethyl- and 6-alkylmethyl-substituted pyrazolopyrimidines are of the formula (I): with the variables as defined in the claims.
    Type: Grant
    Filed: November 19, 2010
    Date of Patent: September 2, 2014
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Martin Hendrix, Lars Bärfacker, Christina Erb, Frank-Thorsten Hafner, Heike Heckroth, Dagmar Karthaus, Adrian Tersteegen, Franz-Josef van der Staay, Marja van Kampen
  • 6-arylmethyl substituted pyrazolo[3,4-d]pyrimidines
    Patent number: 8809348
    Abstract: The invention relates to novel 6-arylmethyl-substituted pyrazolopyrimidines, process for their preparation and their use for producing medicaments for improving perception, concentration, learning and/or memory.
    Type: Grant
    Filed: October 16, 2009
    Date of Patent: August 19, 2014
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Martin Hendrix, Lars Barfacker, Christine Erb, Frank-Thorsten Hafner, Heike Heckroth, Dagmar Karthaus, Adrian Tersteegen, Franz-Josef van der Staay, Marja van Kampen
  • Alkyl-substituted pyrazolopyrimidines
    Patent number: 8741907
    Abstract: The invention relates to alkyl-substituted pyrazolopyrimidines, process for their preparation, and the use thereof for producing medicaments for improving learning and/or memory. The alkyl-substituted pyrazolopyrimidines are of the formula (I): with the variables as defined in the claims.
    Type: Grant
    Filed: July 29, 2011
    Date of Patent: June 3, 2014
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Martin Hendrix, Frank-Gerhard Böβ, Nils Burkhardt, Christina Erb, Adrian Tersteegen, Marja Van Kampen
  • Substituted pyridines, and use thereof as GSK3 inhibitors
    Patent number: 8664246
    Abstract: The invention relates to substituted pyridines and to processes for preparation thereof, and to the use thereof for production of medicaments for treatment and/or prophylaxis of diseases, especially of haematological disorders, preferably of leukopenia and neutropenia.
    Type: Grant
    Filed: July 21, 2009
    Date of Patent: March 4, 2014
    Assignee: Bayer Intellectual Property GmbH
    Inventors: Stephan Siegel, Andreas Wilmen, Niels Svenstrup, Mark Jean Gnoth, Adrian Tersteegen, Ulrich Rester
  • BINDING PROTEINS TO INHIBITORS OF COAGULATION FACTORS
    Publication number: 20140050743
    Abstract: The present invention relates to the identification and use of antigen-binding regions, antibodies, antigen-binding antibody fragments and antibody mimetics, neutralizing the anti-coagulant effect of an anticoagulant in vitro and/or in vivo. Antibodies and functional fragments of the invention and antibody mimetics can be used to specifically reverse the pharmacological effect of an anticoagulant e.g. a FXa inhibitor for therapeutic (antidote) and/or diagnostic purposes. The invention also provides nucleic acid sequences encoding foregoing molecules, vectors containing the same, pharmaceutical compositions and kits with instructions for use.
    Type: Application
    Filed: January 17, 2012
    Publication date: February 20, 2014
    Applicant: BAYER INTELLECTUAL PROPERTY GMBH
    Inventors: Frank Dittmer, Anja Buchmüller, Christoph Gerdes, Adrian Tersteegen, Mark Jean Gnoth, Lars Linden, Axel Harrenga, Joanna Grudzinska-Goebel, Mario Jeske, Martina Schäfer, Jörg Birkenfeld, Holger Paulsen, Ricarda Finnern, Anke Mayer-Bartschmid, Andrea Eicker, Simone Greven, Susanne Steinig
  • 6-cyclylmethyl-and 6-alkylmethyl-substituted pyrazolepyrimidines
    Patent number: 8642605
    Abstract: The invention relates to novel 6-cyclylmethyl- and 6-alkylmethyl-substituted pyrazolopyrimidines, process for their preparation and their use for producing medicaments for improving perception, concentration, learning and/or memory. The pyrazolopyrimidine compounds are within the formula (I) as described herein.
    Type: Grant
    Filed: September 15, 2011
    Date of Patent: February 4, 2014
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Martin Hendrix, Lars Bärfacker, Christina Erb, Frank-Thorsten Hafner, Heike Heckroth, Dagmar Karthaus, Adrian Tersteegen, Franz-Josef van der Staay, Marja van Kampen
  • Substituted annellated pyrimidines and use thereof
    Publication number: 20130338137
    Abstract: The present application relates to novel substituted annellated pyrimidines, methods for production thereof, use thereof alone or in combinations for treating and/or preventing diseases and use thereof for the production of medicinal products for treating and/or preventing diseases, in particular for treating and/or preventing cardiovascular diseases.
    Type: Application
    Filed: August 30, 2012
    Publication date: December 19, 2013
    Applicant: BAYER INTELLECTUAL PROPERTY GMBH
    Inventors: Markus FOLLMANN, Johannes-Peter STASCH, Gorden REDLICH, Nils GRIEBENOW, Dieter LANG, Frank WUNDER, Walter HÜBSCH, Niels LINDNER, Alexandros VAKALOPOULOS, Adrian TERSTEEGEN
  • SUBSTITUTED IMIDAZO- AND TRIAZOLOPYRIMIDINES, IMIDAZO- AND PYRAZOLOPYRAZINES AND IMIDAZOTRIAZINES
    Publication number: 20130296343
    Abstract: The invention relates to substituted imidazo- and triazolopyrimidines, imidazo- and pyrazolopyrazines and imidazotriazines and processes for their preparation, and their use for the manufacture of medicaments for the treatment and/or prophylaxis of diseases, in particular of hematological disorders, preferably of leukopenias and neutropenias.
    Type: Application
    Filed: April 8, 2013
    Publication date: November 7, 2013
    Inventors: Stephan SIEGEL, Andreas WILMEN, Niels SVENSTRUP, Mark Jean GNOTH, Adrian TERSTEEGEN, Ulrich RESTER
  • IMIDAZO-, PYRAZOLOPYRAZINES AND IMIDAZOTRIAZINES AND THEIR USE
    Publication number: 20130261115
    Abstract: The invention relates to substituted imidazo-, pyrazolopyrazines and imidazotriazines and processes for their preparation, and their use for the manufacture of medicaments for the treatment and/or prophylaxis of diseases, in particular of hematological disorders, preferably of leukopenias and neutropenias.
    Type: Application
    Filed: May 30, 2013
    Publication date: October 3, 2013
    Inventors: Stephan SIEGEL, Andreas WILMEN, Susanne RÖHRIG, Niels SVENSTRUP, Mark Jean GNOTH, Stefan HEITMEIER, Ulrich RESTER, Adrian TERSTEEGEN, Michael GERISCH
  • Substituted tricyclic compounds and methods of use thereof
    Patent number: 8524722
    Abstract: This invention relates to novel compounds and processes for their preparation, methods of treating diseases, particularly cancer, comprising administering said compounds, and methods of making pharmaceutical compositions for the treatment or prevention of disorders, particularly cancer.
    Type: Grant
    Filed: September 2, 2008
    Date of Patent: September 3, 2013
    Assignee: Bayer Intellectual Property GmbH
    Inventors: Hartmut Schirok, Ying Li-Sommer, Michael Brands, Mario Lobell, Adrian Tersteegen, Herbert Himmel, Karl-Heinz Schlemmer, Dieter Lang, Kirstin Petersen, Matthias Renz, Dominik Mumberg, Jens Hoffmann, Gerhard Siemeister, Ulf Bömer
  • Imidazo-, pyrazolopyrazines and imidazotriazines and their use
    Patent number: 8476267
    Abstract: The invention relates to substituted imidazo-, pyrazolopyrazines and imidazotriazines and processes for their preparation, and their use for the manufacture of medicaments for the treatment and/or prophylaxis of diseases, in particular of hematological disorders, preferably of leukopenias and neutropenias.
    Type: Grant
    Filed: June 28, 2008
    Date of Patent: July 2, 2013
    Assignee: Bayer Intellectual Property GmbH
    Inventors: Stephan Siegel, Andreas Wilmen, Susanne Röhrig, Niels Svenstrup, Mark Jean Gnoth, Stefan Heitmeier, Ulrich Rester, Adrian Tersteegen, Michael Gerisch
  • Substituted imidazo- and triazolopyrimidines, imidazo- and pyrazolopyrazines and imidazotriazines
    Patent number: 8436003
    Abstract: The invention relates to substituted triazolopyrimidines of the formula processes for their preparation, and their use for the treatment of hematological disorders.
    Type: Grant
    Filed: May 2, 2009
    Date of Patent: May 7, 2013
    Assignee: Bayer Intellectual Property GmbH
    Inventors: Stephan Siegel, Andreas Wilmen, Niels Svenstrup, Mark Jean Gnoth, Adrian Tersteegen, Ulrich Rester
  • Cyanopyrimidinones
    Patent number: 8431573
    Abstract: The invention relates to novel cyanopyrimidinones, process for their preparation, and the use thereof for producing medicaments for improving perception, concentration, learning and/or memory.
    Type: Grant
    Filed: May 2, 2011
    Date of Patent: April 30, 2013
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Martin Hendrix, Lars Bärfacker, Heike Heckroth, Dagmar Karthaus, Adrian Tersteegen
  • Substituted oxazolidinones and their use
    Patent number: 8383822
    Abstract: The invention relates to novel substituted oxazolidinones, to processes for their preparation, to their use for the treatment and/or prophylaxis of diseases and their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular of thromboembolic disorders.
    Type: Grant
    Filed: June 7, 2008
    Date of Patent: February 26, 2013
    Assignee: Bayer Intellectual Property GmbH
    Inventors: Swen Allerheiligen, Marcus Bauser, Dirk Heimbach, Stefan Heitmeier, Mark Jean Gnoth, Christoph Gerdes, Georges Von Degenfeld, Susanne Röhrig, Ulrich Rester, Elke Dittrich-Wengenroth, Uwe Saatmann, Adrian Tersteegen, Joachim Krüger, Holger Paulsen