Patents by Inventor Adriana Ines Larriera Moreno

Adriana Ines Larriera Moreno has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9150907
    Abstract: A microfluidic flow cell subassembly, which may be assembled into a flow cell having fluidic connections outside of the main substrate, is described for encapsulating a sample to allow for subsequent controlled delivery of reagents to the sample, such as multiplexed in situ biomarker staining and analysis. The fluidic connectors are thin film fluidic connectors capable of connecting to a fluid delivery system. The subassembly may be sealed against a solid support to form a flow cell. Methods of use are also disclosed.
    Type: Grant
    Filed: May 15, 2014
    Date of Patent: October 6, 2015
    Assignee: General Electric Company
    Inventors: Kashan Ali Shaikh, Mengli Wang, Adriana Ines Larriera Moreno, Jessica Godin Karp, Christine Lynne Pitner
  • Publication number: 20150198580
    Abstract: The invention provides a coverslip for automated decoverslipping of a tissue bearing slide comprising a horizontal base portion having a length, width, and height, at least two side wall portions extending downward from opposite sides of the base portion each having a length and width and h; and wherein the total wall volume to base volume ratio is greater than or equal to approximately 0.025.
    Type: Application
    Filed: January 13, 2014
    Publication date: July 16, 2015
    Applicant: GENERAL ELECTRIC COMPANY
    Inventors: Brian James Grimmond, Brian Christopher Bales, Alex David Corwin, Adriana Ines Larriera Moreno, Christine Lynne Pitner
  • Patent number: 9080941
    Abstract: A microfluidic flow cell subassembly, which may be assembled into a flow cell having fluidic connections outside of the main substrate, is described for encapsulating a sample to allow for subsequent controlled delivery of reagents to the sample, such as multiplexed in situ biomarker staining and analysis. As configured, the subassembly comprises a substrate layer forms a flexible optically transparent lid which is capable of bending in either direction to alter the internal dimensions of the subassembly. Methods of use are also disclosed.
    Type: Grant
    Filed: May 14, 2014
    Date of Patent: July 14, 2015
    Assignee: General Electric Company
    Inventors: Kashan Ali Shaikh, Mengli Wang, Adriana Ines Larriera Moreno, Jessica Godin Karp, Christine Lynne Pitner
  • Publication number: 20140248617
    Abstract: A microfluidic flow cell subassembly, which may be assembled into a flow cell having fluidic connections outside of the main substrate, is described for encapsulating a sample to allow for subsequent controlled delivery of reagents to the sample, such as multiplexed in situ biomarker staining and analysis. As configured, the subassembly comprises a substrate layer forms a flexible optically transparent lid which is capable of bending in either direction to alter the internal dimensions of the subassembly. Methods of use are also disclosed.
    Type: Application
    Filed: May 14, 2014
    Publication date: September 4, 2014
    Applicant: GENERAL ELECTRIC COMPANY
    Inventors: Kashan Ali Shaikh, Mengli Wang, Adriana Ines Larriera Moreno, Jessica Godin Karp, Christine Lynne Pitner
  • Publication number: 20140248618
    Abstract: A microfluidic flow cell subassembly, which may be assembled into a flow cell having fluidic connections outside of the main substrate, is described for encapsulating a sample to allow for subsequent controlled delivery of reagents to the sample, such as multiplexed in situ biomarker staining and analysis. The fluidic connectors are thin film fluidic connectors capable of connecting to a fluid delivery system. The subassembly may be sealed against a solid support to form a flow cell. Methods of use are also disclosed.
    Type: Application
    Filed: May 15, 2014
    Publication date: September 4, 2014
    Applicant: GENERAL ELECTRIC COMPANY
    Inventors: Kashan Ali Shaikh, Mengli Wang, Adriana Ines Larriera Moreno, Jessica Godin Karp, Christine Lynne Pitner
  • Publication number: 20140055853
    Abstract: An open top microfluidic device comprising a microfluidic slide carrier and one or more multiplexing stations is provided which allows sequential staining and imaging without the need for using or removing a coverslip on a mounted biological sample.
    Type: Application
    Filed: August 27, 2012
    Publication date: February 27, 2014
    Applicant: GENERAL ELECTRIC COMPANY
    Inventors: Alex David Corwin, Robert John Filkins, Kashan Ali Shaikh, Adriana Ines Larriera Moreno