Patents by Inventor Adriano Guiotto

Adriano Guiotto has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of preparing photochemotherapic alkylangelicin compounds
    Patent number: 5179217
    Abstract: The alkylangelicins according to the invention are obtained starting from an umbelliferone, in which the 6-position is already substituted by an alkyl group; in such a way the 7-allyloxy or 7-acyloxy umbelliferone intermediates can form by transposition of the allyl or acyl group only the 8-allyl and 8-acyl derivatives, and therefore the presence, even in traces, of psoralens is absolutely excluded in the subsequent synthetic steps.The 6-alkylangelicins thus obtained are particularly usable for the photochemotherapy of psoriasys and of other skin diseases characterized by cellular hyperproliferation, as well as for the photochemotherapy of vitiligo and of alopecia aerata.
    Type: Grant
    Filed: December 27, 1990
    Date of Patent: January 12, 1993
    Inventors: Francarosa Baccichetti, Franco Bordin, Carlo Monti-Bragadin, Francesco Carlassare, Giovanni Recchia, Giovanni Rodighiero, Paolo Rodighiero, Daniela Vedaldi, Mario Cristofolini, Francesco Dall'Acqua, Adriano Guiotto, Giovanni Pastorini
  • Photochemotherapic method of treating psoriasis by using methylangelicin compounds
    Patent number: 5001147
    Abstract: The alkylangelicins according to the invention are obtained starting from an umbelliferone, in which the 6-position is already substituted by an alkyl group; in such a way the 7-allyloxy or 7-acyloxy umbelliferone intermediates can form by transposition of the allyl or acyl group only the 8-allyl and 8-acyl derivatives, and therefore the presence, even in traces, of psoralens is absolutely excluded in the subsequent synthetic steps.The 6-alkylangelicins thus obtained are particularly usable for the photochemotherapy of psoriasys and of other skin diseases characterized by cellular hyperproliferation, as well as for the photochemotherapy of vitiligo and of alopecia aerata.
    Type: Grant
    Filed: May 16, 1988
    Date of Patent: March 19, 1991
    Assignee: Consiglio Nazionale delle Ricerche
    Inventors: Francarosa Baccichetti, Franco Bordin, Francesco Carlassare, Mario Cristofolini, Francesco Dall'Acqua, Adriano Guiotto, Carlo M. Bragadin, Giovanni Pastorini, Giovanni Recchia, Giovanni Rodighiero, Paola Rodighiero, Daniela Vedaldi
  • Furocoumarin for the photochemotherapy of psoriasis and related skin diseases
    Patent number: 4312883
    Abstract: A class of alkyl-substituted angular flurocoumarins, sometimes termed alkylangelicins, useful in the photochemotherapy of psoriasis and in other skin diseases characterized by cellular hyperproliferation or lack of skin pigmentation is disclosed for topical application or systemic administration. Compared with conventional psoralens the described compounds exhibit a lower risk of skin cancer, absence of phototoxicity problems anderithema to the patient so treated. One preferred compound is 5-methylangelicin.
    Type: Grant
    Filed: August 15, 1980
    Date of Patent: January 26, 1982
    Assignee: Consiglio Nazionale delle Ricerche
    Inventors: Francarosa Baccichetti, Franco Bordin, Francesco Carlassare, Francesco Dall'Acqua, Adriano Guiotto, Giovanni Pastorini, Giovanni Rodighiero, Paolo Rodighiero, Daniela Vedaldi