Abstract: A use in a medical device of at least one salt of organic acid(s), and preferably a benzoate or a sorbate, as an antimicrobial agent is disclosed, and in particular for the manufacturing of an antimicrobial coating for a medical device, e.g., hydrophyllic urinary catheters, for the prevention of bacterial infection. The pH of the hydrophilic coating may be controlled to be in the range 4.0-8.0, preferably in the range 5.0-6.0, and preferably to be below 7.0. The pH of the hydrophilic coating could be controlled by means of a pH buffer, and preferably a citrate or phosphate buffer. A salt of organic acid in combination with a pH buffer has proven surprisingly efficient for inhibition of bacterial growth, and for prevention of bacterial infections.

Abstract: A catheter assembly (110, 210) comprising a catheter (130, 230) and a receptacle (120, 220) is disclosed. The receptacle is arranged to accommodate at least part of said catheter and having at least one opening (123) for withdrawal of said catheter. Further, the receptacle is provided with an antimicrobial compound (301) at least in the vicinity of the opening and at least on the outer surface of the receptacle, said antimicrobial compound inhibiting microbes from being transferred to said catheter while being withdrawn through said at least one opening.

Abstract: There is disclosed a medical device, such as a urinary catheter, comprising a substrate material, a hydrophilic surface coating, e.g. comprising polyvinylpyrrolidone (PVP), arranged on at least a part of the surface of said substrate material, and an antibacterial layer comprising oligodynamic metal arranged between the substrate material and the hydrophilic surface coating. Further, the hydrophilic surface coating has a thickness large enough to provide a controlled release of oligodynamic metal ions through the hydrophilic surface coating, such as a thickness when dry that exceeds 3 ?m. Hereby, the variation in the release of the oligodynamic metal ions is significantly reduced, enabling an improved control of the release. A corresponding method is also disclosed.

Abstract: A catheter assembly (110, 210) comprising a catheter (130, 230) and a receptacle (120, 220) is disclosed. The receptacle is arranged to accommodate at least part of said catheter and having at least one opening (123) for withdrawal of said catheter. Further, the receptacle is provided with an antimicrobial compound (301) at least in the vicinity of the opening and at least on the outer surface of the receptacle, said antimicrobial compound inhibiting microbes from being transferred to said catheter while being withdrawn through said at least one opening.

Abstract: A use in a medical device of at least one salt of organic acid(s), and preferably a benzoate or a sorbate, as an antimicrobial agent is disclosed, and in particular for the manufacturing of an antimicrobial coating for a medical device for the prevention of bacterial infection. This is very useful in medical devices having a hydrophilic coating, such hydrophilic urinary catheters. It is further preferred that the pH of the hydrophilic coating is controlled to be in the range 4.0-8.0, and preferably in the range 5.0-6.0. It is also preferred that the pH of the hydrophilic coating is controlled to be below 7.0. The pH of the hydrophilic coating could be controlled by means of a pH buffer, and preferably a citrate or phosphate buffer. Specifically, the provision of the salt of organic acid in combination with a pH buffer has proven surprisingly efficient for inhibition of bacterial growth, and for prevention of bacterial infections.