Abstract: The present disclosure relates to improved compositions that are effective in management of disorders caused by pathogenic amyloid deposits. The disclosure discloses a composition comprising carboxylated osteocalcin which is effective in therapeutic clearance of abnormal amyloid deposits.

Abstract: Provided herein are methods and systems to provide for parallax correction for multiple eye-points in a single viewpoint within a Homogeneous 3-Dimensional (3D) virtual environment. In preferred embodiments, the systems and methods are used as part of a virtual training environment where multiple participants are participating simultaneously. The methods and systems render multiple objects from multiple eye-points by creating custom projection matrix for each eye-point. Each rendered object is overlaid over the background and other images rendered with the standard eye-point projection matrix. Preferred embodiments use the same view matrix for all renderings.

Abstract: Provided herein are methods and systems to provide for parallax correction for multiple eye-points in a single viewpoint within a Homogeneous 3-Dimensional (3D) virtual environment. In preferred embodiments, the systems and methods are used as part of a virtual training environment where multiple participants are participating simultaneously. The methods and systems render multiple objects from multiple eye-points by creating custom projection matrix for each eye-point. Each rendered object is overlaid over the background and other images rendered with the standard eye-point projection matrix. Preferred embodiments use the same view matrix for all renderings.

Abstract: A system and method for collecting computer application usage data from a plurality of client devices. The system may include a monitoring program executable on each of the plurality of client devices. The monitoring program may be configured to receive from a server via a computer network monitoring data including one or more application identifiers, and to identify one or more target application programs executed on the client device as matching one of the identifiers. The monitoring program may further be configured to gather usage data for the target application program over a period of time, and send a message back to the server including the usage data. Reports may be generated based on the usage data.

Abstract: A system and method for collecting computer application usage data from a plurality of client devices. The system may include a monitoring program executable on each of the plurality of client devices. The monitoring program may be configured to receive from a server via a computer network monitoring data including one or more application identifiers, and to identify one or more target application programs executed on the client device as matching one of the identifiers. The monitoring program may further be configured to gather usage data for the target application program over a period of time, and send a message back to the server including the usage data. Reports may be generated based on the usage data.

Abstract: A component based Application Middleware Framework (20) for modifying Application Middleware Framework (AMF) component services includes an interceptor (70) for intercepting an interface event being transmitted from a software management application (14a-14e) to a software component (40, 42). A rules database (48, 78) stores AMF component service modifying rules, and an adaptor (72) modifies the interface event based on the AMF component service modifying rules stored in the rules database (48, 70). A policy engine (74) attempts to match the interface event with the AMF component service modifying rules stored in the rules database (48, 70), and subsequently coordinates the modification of the AMF component service by the adaptor (72) when the policy engine (74) matches the interface event with at least one of the AMF component service modifying rules stored in the rules database (48, 70).