Abstract: An oral fluid collection and transfer device comprises a collection device (10) and a test cartridge (100). The collection device includes a frame or chassis (14), and an absorbing pad (12) for absorbing oral fluid and which is secured around part of the frame with part of the frame protruding from the pad. A collapsible cover (16) covers the absorbing means and has apertures (68) for the ingress of oral fluid into contact with the absorbing pad. A cap (18) covers the part of the frame protruding from the absorbing pad. The cap and the cover latch together to surround the frame and the absorbing pad. The device also includes a fluid adequacy indicator (20) in the form of an electrical circuit with an LED (66) which is completed when the absorbing means has absorbed a predetermined volume of oral fluid.

Abstract: An analyte collection apparatus is provided, comprising a gripper; and a compressible analyte collecting portion releasably gripped by the gripper, wherein the gripper exerts a force to grip and compress the analyte collecting portion. The analyte collecting portion can be immersed in a buffer solution whilst in the partially compressed state, and allowed to expand therein, reducing the time required for non-specific binding of analytes to the analyte collecting portion. The analyte collection device facilitates indirect handling of the collected analyte, preventing cross-contamination, and also allows for quick on-site testing.

Abstract: An oral fluid collection and transfer device comprises a collection device (10) and a test cartridge (100). The collection device includes a frame or chassis (14), and an absorbing pad (12) for absorbing oral fluid and which is secured around part of the frame with part of the frame protruding from the pad. A collapsible cover (16) covers the absorbing means and has apertures (68) for the ingress of oral fluid into contact with the absorbing pad. A cap (18) covers the part of the frame protruding from the absorbing pad. The cap and the cover latch together to surround the frame and the absorbing pad. The device also includes a fluid adequacy indicator (20) in the form of an electrical circuit with an LED (66) which is completed when the absorbing means has absorbed a predetermined volume of oral fluid. The test cartridge (100) has a collection chamber (110) to allow insertion of the collection device into the test cartridge. A test strip (150) is used to for test the oral fluid for the presence of analytes.

Abstract: There is provided a novel medical kit which overcomes the problem with non-specific binding and interaction, thus providing a highly reliable method for qualitative or quantitative determination of a drug in a biological fluid. Said medical kit comprises a first part coated with a drug conjugate, and a second part which contains a labelled anti-drug antibody, said labelled anti-drug antibody is labelled with gold material and/or latex particles, and is adapted for receiving said biological fluid.