Patents by Inventor Ahmed Mansouri

Ahmed Mansouri has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for producing a population of pancreatic beta-cells
    Patent number: 9708608
    Abstract: The present invention relates to an in vitro or ex vivo method for producing a population of pancreatic beta-cells, comprising the step of inhibiting the expression or the activity of Arx in a population of pancreatic alpha-cells. The present invention also relates to method for inducing the conversion of pancreatic alpha-cells in pancreatic beta-cells in a patient in need thereof.
    Type: Grant
    Filed: September 16, 2013
    Date of Patent: July 18, 2017
    Assignees: Institut National de la Sante et de la Recherche Medicale (INSERM), Centre National de la Recherche Scientific (CNRS), Universite Nice Sophia Antipolis
    Inventors: Patrick Collombat, Keith Al-Hasani, Monica Courtney, Nouha Ben-Ohtman, Elisabet Gjernes, Ahmed Mansouri
  • METHODS FOR PRODUCING A POPULATION OF PANCREATIC BETA-CELLS
    Publication number: 20150240235
    Abstract: The present invention relates to an in vitro or ex vivo method for producing a population of pancreatic beta-cells, comprising the step of inhibiting the expression or the activity of Arx in a population of pancreatic alpha-cells. The present invention also relates to method for inducing the conversion of pancreatic alpha-cells in pancreatic beta-cells in a patient in need thereof.
    Type: Application
    Filed: September 16, 2013
    Publication date: August 27, 2015
    Inventors: Patrick Collombat, Keith Al-Hasani, Monica Courtney, Nouha Ben-Ohtman, Elisabet Gjernes, Ahmed Mansouri
  • PRODUCTION OF BETA-CELLS
    Publication number: 20150204850
    Abstract: The present invention relates to in vitro and in vivo methods for the generation of pancreatic ?-cells, comprising the step of providing at least one pancreatic ?-cell or at least one precursor cell with Pax-4 or a nucleic acid encoding Pax-4. Furthermore, the invention relates to a screening method for the screening of a pancreatic-?-cell phenotype-inducing compound, comprising the step of contacting at least one pancreatic ?-cell or at least one precursor cell with a given compound, and testing whether said compound is capable of inducing a pancreatic-?-cell phenotype.
    Type: Application
    Filed: December 15, 2014
    Publication date: July 23, 2015
    Inventors: Ahmed MANSOURI, Patrick COLLOMBAT
  • Production of beta-cells
    Publication number: 20120231454
    Abstract: The present invention relates to in vitro and in vivo methods for the generation of pancreatic ?-cells, comprising the step of providing at least one pancreatic ?-cell or at least one precursor cell with Pax-4 or a nucleic acid encoding Pax-4. Furthermore, the invention relates to a screening method for the screening of a pancreatic-?-cell phenotype-inducing compound, comprising the step of contacting at least one pancreatic ?-cell or at least one precursor cell with a given compound, and testing whether said compound is capable of inducing a pancreatic-?-cell phenotype.
    Type: Application
    Filed: July 30, 2010
    Publication date: September 13, 2012
    Inventors: Ahmed Mansouri, Patrick Collombat