Patents by Inventor Aijin Shen

Aijin Shen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Zwitterionic stationary phase for hydrophilic interaction liquid chromatography and preparation method thereof
    Patent number: 9138721
    Abstract: A type of liquid chromatographic stationary phase and preparation method thereof, the bonding terminal of the chromatographic stationary phase is zwitterionic functional group. The preparation method includes the following steps, alkenyl or alkynyl silane is bonded onto the surface of silica based on the horizontal polymerization approach to obtain alkenyl- or alkynyl-modified silica. Then the thiol click reaction with zwitterionic compound containing thiol group is performed to obtain the zwitterionic hydrophilic interaction chromatographic stationary phase. The present stationary phase possesses both zwitterionic characteristics and excellent hydrophilicity. It can be widely applied in the separation of variety of samples.
    Type: Grant
    Filed: November 25, 2011
    Date of Patent: September 22, 2015
    Assignee: DALIAN INSTITUTE OF CHEMICAL PHYSICS, CHINESE ACADEMY OF SCIENCES
    Inventors: Xinmiao Liang, Aijin Shen, Zhimou Guo, Long Yu, Liwei Cao
  • ZWITTERIONIC STATIONARY PHASE FOR HYDROPHILIC INTERACTION LIQUID CHROMATOGRAPHY AND PREPARATION METHOD THEREOF
    Publication number: 20130324700
    Abstract: A type of liquid chromatographic stationary phase and preparation method thereof, the bonding terminal of the chromatographic stationary phase is zwitterionic functional group. The preparation method includes the following steps, alkenyl or alkynyl silane is bonded onto the surface of silica based on the horizontal polymerization approach to obtain alkenyl- or alkynyl-modified silica. Then the thiol click reaction with zwitterionic compound containing thiol group is performed to obtain the zwitterionic hydrophilic interaction chromatographic stationary phase. The present stationary phase possesses both zwitterionic characteristics and excellent hydrophilicity. It can be widely applied in the separation of variety of samples.
    Type: Application
    Filed: November 25, 2011
    Publication date: December 5, 2013
    Applicant: Dailian Institute of Chemical Physics, Chinese Aca of Sciences
    Inventors: Xinmiao Liang, Aijin Shen, Zhimou Guo, Long Yu, Liwei Cao