Patents by Inventor Ainara Vallejo Illarramendi

Ainara Vallejo Illarramendi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Triazoles for regulating intracellular calcium homeostasis
    Patent number: 11377427
    Abstract: The present invention relates to 1,2,3-triazoles of formula: useful for improving or restoring the intracellular calcium homeostasis and RyR-calstabin binding function in human and animal cells. The present invention also relates to methods for synthesizing said compounds, to pharmaceutical compositions containing them, and to the use thereof for preventing or treating skeletal muscle, heart and nervous system disorders.
    Type: Grant
    Filed: May 23, 2017
    Date of Patent: July 5, 2022
    Assignees: UNIVERSIDAD DEL PAIS VASCO, ADMINISTRACION GENERAL DE LA COMUNIDAD AUTONOMA DE EUSKADI
    Inventors: Ainara Vallejo Illarramendi, Adolfo Jose Lopez De Munain Arregi, Pablo Ferron Celma, Jesus Maria Aizpurua Iparraguirre, Aitziber Irastorza Epelde, Jose Ignacio Miranda Murua, Ivan Toral Ojeda, Garazi Aldanondo Aristizabal
  • TRIAZOLES FOR REGULATING INTRACELLULAR CALCIUM HOMEOSTASIS
    Publication number: 20200317625
    Abstract: The present invention relates to 1,2,3-triazoles of formula: useful for improving or restoring the intracellular calcium homeostasis and RyR-calstabin binding function in human and animal cells. The present invention also relates to methods for synthesizing said compounds, to pharmaceutical compositions containing them, and to the use thereof for preventing or treating skeletal muscle, heart and nervous system disorders.
    Type: Application
    Filed: May 23, 2017
    Publication date: October 8, 2020
    Inventors: Ainara VALLEJO ILLARRAMENDI, Adolfo Jose LOPEZ DE MUNAIN ARREGI, Pablo FERRON CELMA, Jesus Maria AIZPURUA IPARRAGUIRRE, Aitziber IRASTORZA EPELDE, Jose Ignacio MIRANDA MURUA, Ivan TORAL OJEDA, Garazi ALDANONDO ARISTIZABAL
  • Method for the diagnosis and prognosis of demyelinating diseases
    Patent number: 7879568
    Abstract: The present invention refers to the use of glutamate transporters, glutamate and EGF to detect the presence of demyelinating diseases in a subject, to determine the status or severity of the same or to monitor the effects of a therapy administered to a subject who suffers from such diseases; to the use of the said markers for the searching, identification, development and evaluation of the efficacy of compounds for the treatment of such diseases, with a view to developing new drugs; to the use of compounds which promote the expression of the EAAT1 and EAAT2 transporters, as well as EGF for the treatment of demyelinating diseases. In a preferred embodiment, the methods and compounds of the invention are applicable to MS.
    Type: Grant
    Filed: May 22, 2006
    Date of Patent: February 1, 2011
    Assignee: Universidad Del Pais Vasco
    Inventors: Carlos Matute Almau, María Domercq García, Alberto Pérez Samartín, Fernando Pérez Cerdá, Ainara Vallejo Illarramendi, Estibaliz Etxebarria Galnares, Ormaetxea Olatz Pampliega, Pablo Villoslada Díaz, Alfredo Rodríguez-Antigüedad Zarranz
  • Method For the Diagnosis and Prognosis of Demyelinating Diseases and For the Development of Medicaments Against Demyelinating Diseases
    Publication number: 20080200384
    Abstract: The present invention refers to the use of glutamate transporters, glutamate and EGF to detect the presence of demyelinating diseases in a subject, to determine the status or severity of the same or to monitor the effects of a therapy administered to a subject who suffers from such diseases; to the use of the said markers for the searching, identification, development and evaluation of the efficacy of compounds for the treatment of such diseases, with a view to developing new drugs; to the use of compounds which promote the expression of the EAAT1 and EAAT2 transporters, as well as EGF for the treatment of demyelinating diseases. In a preferred embodiment, the methods and compounds of the invention are applicable to MS.
    Type: Application
    Filed: May 22, 2006
    Publication date: August 21, 2008
    Applicant: UNIVERSIDAD DEL PAlS VASCO
    Inventors: Carlos Matute Almau, Maria Domercq Garcia, Alberto Perez Samartin, Fernando Perez Cerda, Ainara Vallejo Illarramendi, Estibaliz Etxebarria Galnares, Ormaetxea Olatz Pampliega, Pablo Villoslada Diaz, Alfredo Rodriguez-Antiguedad Zarranz
  • Method for the in Vitro Diagnosis and Prognosis of Demyelinating Diseases, and for the Development of Drugs Against Demyelinating Diseases
    Publication number: 20080113347
    Abstract: The present invention refers to an in vitro method for detecting the presence of demyelinating diseases in an individual, for determining the stage or severity of said diseases in the individual, or for monitoring the effect of the therapy administered to an individual suffering said diseases; to the search, identification, development and evaluation of efficacy of compounds for therapy of said diseases for the purpose of developing new drugs; as well as to agents inhibiting DUSP6 protein expression and/or activity, and/or the effects of this expression. The methods and agents of the invention are preferably applied to multiple sclerosis.
    Type: Application
    Filed: December 28, 2004
    Publication date: May 15, 2008
    Inventors: Ainara Vallejo Illarramendi, Antonio Martinez Martinez, Usue Ariz Lopez de Castro, Lourdes Osaba Ortiz de Mendibil, Corina Junquera Sanchez-Vallejo, Simon Santa Cruz, Pedro Escudero Garcia de Galdeano, Jorge Ochoa Garay, Laureano Simon Buela, Carlos Matute Almau, Elena Alberdi Alfonso, Maria Victoria Sanchez Gomez, Gaskon Ibarretxe Bilbao, Estibaliz Etxebarria Galnares