Patents by Inventor Aiping Cheng
Aiping Cheng has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Publication number: 20170128434Abstract: Compounds of formula (I) or a pharmaceutically acceptable ester, amide, carbamate or salt thereof, including a salt of such an ester, amide or carbamate in which R1 to R9 have meanings as defined in the Specification, are useful as estrogen receptor ligands.Type: ApplicationFiled: January 17, 2017Publication date: May 11, 2017Inventors: Aiping Cheng, Neeraj Garg, Lars Krüger, Joakim Löfstedt, Eva Koch, Konrad Koehler, Lars Hagberg, Daniel Nöteberg
-
Patent number: 9586891Abstract: Compounds of formula (I) or a pharmaceutically acceptable ester, amide, carbamate or salt thereof, including a salt of such an ester, amide or carbamate in which R1 to R9 have meanings as defined in the Specification, are useful as estrogen receptor ligands.Type: GrantFiled: August 2, 2012Date of Patent: March 7, 2017Assignee: Karo Pharma ABInventors: Aiping Cheng, Neeraj Garg, Lars Krüger, Joakim Löfstedt, Eva Koch, Konrad Koehler, Lars Hagberg, Daniel Nöteberg
-
Publication number: 20140323518Abstract: Compounds of formula (I) or a pharmaceutically acceptable ester, amide, carbamate or salt thereof, including a salt of such an ester, amide or carbamate in which R1 to R9 have meanings as defined in the Specification, are useful as estrogen receptor ligands.Type: ApplicationFiled: August 2, 2012Publication date: October 30, 2014Inventors: Aiping Cheng, Neeraj Garg, Lars Krüger, Joakim Löfstedt, Eva Koch, Konrad Koehler, Lars Hagberg, Daniel Nöteberg
-
Publication number: 20140116641Abstract: The present invention discloses a rotary gas-gas heat exchanger with an isolating air curtain structure of a leak-free sealing system. The rotary gas-gas heat exchanger comprises: a shell; a rotor, which is arranged in said shell and is driven to rotate with respect to said shell; a sealing system, which is arranged between said shell and a spindle of said rotor, and divides the space between said shell and the spindle of said rotor into an original flue gas circulation zone and a clean flue gas circulation zone. Said sealing system comprises two pairs of sealing plates which are located at the upper and lower sides respectively and are opposite to each other. Said two sealing plates are provided with at least one pair of holes which face with each other. Said at least one pair of holes communicate with a fan.Type: ApplicationFiled: July 8, 2012Publication date: May 1, 2014Inventor: Aiping Cheng
-
Patent number: 8710243Abstract: The invention provides a compound of formula(I) or a pharmaceutically acceptable ester, amide, solvate or salt thereof, including a salt of such an ester or amide, and a solvate of such an ester, amide or salt. The invention also provides the use of such compounds in the treatment or prophylaxis of a condition associated with a disease or disorder associated with estrogen receptor activity. Formula(I) wherein R1, R2, R3, R4, R5, R6, R7, R8, R9 and R10 are as defined in the specification.Type: GrantFiled: October 6, 2010Date of Patent: April 29, 2014Assignee: Karo Bio ABInventors: Lars Hagberg, Sandra Gordon, Aiping Cheng, Theresa Apelqvist, Patrik Rhönnstad, Mattias Wennerstål
-
Patent number: 8653072Abstract: The invention provides a compound of formula (I) or a pharmaceutically acceptable ester, amide, carbamate, solvate or salt thereof, including a salt of such an ester, amide or carbamate, and a solvate of such an ester, amide, carbamate or salt. The invention also provides also provides the use of such compounds in the treatment or prophylaxis of a condition associated with a disease or disorder associated with estrogen receptor activity, wherein R1, R2, R3, R5 and R6 are as defined in the specification.Type: GrantFiled: January 11, 2013Date of Patent: February 18, 2014Assignee: Karo Bio ABInventors: Patrik Rhonnstad, Elisabet Kallin, Theresa Apelqvist, Mattias Wennerstal, Aiping Cheng
-
Publication number: 20130131061Abstract: The invention provides a compound of formula (I) or a pharmaceutically acceptable ester, amide, carbamate, solvate or salt thereof, including a salt of such an ester, amide or carbamate, and a solvate of such an ester, amide, carbamate or salt. The invention also provides also provides the use of such compounds in the treatment or prophylaxis of a condition associated with a disease or disorder associated with estrogen receptor activity, wherein R1, R2, R3, R5 and R6 are as defined in the specification.Type: ApplicationFiled: January 11, 2013Publication date: May 23, 2013Applicant: KARO BIO ABInventors: Patrik Rhonnstad, Elisabet Kallin, Theresa Apelqvist, Mattias Wennerstal, Aiping Cheng
-
Patent number: 8367665Abstract: The invention provides a compound of formula (I) or a pharmaceutically acceptable ester, amide, carbamate, solvate or salt thereof, including a salt of such an ester, amide or carbamate, and a solvate of such an ester, amide, carbamate or salt. The invention also provides also provides the use of such compounds in the treatment or prophylaxis of a condition associated with a disease or disorder associated with estrogen receptor activity, wherein R1, R2, R3, R4, R5 and R6 are as defined in the specification.Type: GrantFiled: April 16, 2009Date of Patent: February 5, 2013Assignee: Karo Bio ABInventors: Patrik Rhönnstad, Elisabet Kallin, Theresa Apelqvist, Mattias Wennerstål, Aiping Cheng
-
Publication number: 20120202861Abstract: The invention provides a compound of formula (I) or a pharmaceutically acceptable ester, amide, solvate or salt thereof, including a salt of such an ester or amide, and a solvate of such an ester, amide or salt. The invention also provides the use of such compounds in the treatment or prophylaxis of a condition associated with a disease or disorder associated with estrogen receptor activity. Formula (I) wherein R1, R2, R3, R4, R5, R6, R7, R8, R9 and R10 are as defined in the specification.Type: ApplicationFiled: October 6, 2010Publication date: August 9, 2012Applicant: KARO BIO ABInventors: Mattias Wennerstål, Patrik Rhönnstad, Aiping Cheng, Sandra Gordon, Theresa Apelqvist, Lars Hagberg
-
Publication number: 20110201555Abstract: The invention provides a compound of formula (I) or a pharmaceutically acceptable ester, amide, solvate or salt thereof, including a salt of such an ester or amide, and a solvate of such an ester, amide or salt. The invention also provides also provides the use of such compounds in the treatment or prophylaxis of a condition associated with a disease or disorder associated with estrogen receptor activity. wherein R1, R2, R3, R4, R5, R6, R7, R8, R9 , R10 and R11 are as defined in the specification.Type: ApplicationFiled: September 18, 2009Publication date: August 18, 2011Inventors: Patrik Rhönnstad, Theresa Apelqvist, Mattias Wennerstål, Aiping Cheng, Sandra Gordon
-
Publication number: 20110190294Abstract: The invention provides a compound of formula (I) or a pharmaceutically acceptable ester, amide, carbamate, solvate or salt thereof, including a salt of such an ester, amide or carbamate, and a solvate of such an ester, amide, carbamate or salt. The invention also provides also provides the use of such compounds in the treatment or prophylaxis of a condition associated with a disease or disorder associated with estrogen receptor activity, wherein R1, R2, R3, R4, R5 and R6 are as defined in the specification.Type: ApplicationFiled: April 16, 2009Publication date: August 4, 2011Inventors: Patrik Rhönnstad, Elisabet Kallin, Theresa Apelqvist, Mattias Wennerstål, Aiping Cheng
-
Publication number: 20100004271Abstract: The invention provides Compounds of formula (I) or pharmaceutically acceptable esters, amides, solvates or salts thereof, including salts of such esters or amides, and solvates of such esters, amides or salts, wherein R3, R4, G, Y, W and R5 are as defined in the specification. The invention also provides the use of such Compounds in the treatment or Prophylaxis of a condition associated with a disease or disorder associated with thyroid receptor activity.Type: ApplicationFiled: July 4, 2006Publication date: January 7, 2010Applicant: KARO BIO ABInventors: Ana Maria Garcia Collazo, Eva Kristina Koch, Anton Joakim Lofstedt, Aiping Cheng, Thomas Fredrik Hansson, Edouard Zamaratski
-
Publication number: 20090318514Abstract: The invention provides the use of compounds of formula (I) or pharmaceutically acceptable esters, amides, solvates or salts thereof, including salts of such esters or amides, and solvates of such esters, amides or salts, for the manufacture of a medicament for the treatment or prophylaxis of a condition that may be treated with a thyroid receptor agonist or partial agonist wherein R1, R2, R3, R4, Y, W and R5 are as defined in the specification. The invention also provides compounds of formula (Ia) or pharmaceutically acceptable esters, amides, solvates or salts thereof, including salts of such esters or amides, and solvates of such esters, amides or salts, formula (Ia) wherein R1, R2, R3, R4, Y, W and R5 are as defined in the specification.Type: ApplicationFiled: May 3, 2007Publication date: December 24, 2009Inventors: Ana Maria Garcia Collazo, Eva Kristina Koch, Anton Joakim Löfstedt, Aiping Cheng, Sandra Gordon, Tomas Fredrik Hansson
-
Patent number: 7592363Abstract: This invention provides compounds of Formula (I) or (Ia): that are useful in the treatment or inhibition of LXR mediated diseases.Type: GrantFiled: August 1, 2005Date of Patent: September 22, 2009Assignee: WyethInventors: Robert J. Steffan, Edward M. Matelan, Stephen M. Bowen, John W. Ullrich, Jay E. Wrobel, Edouard Zamaratski, Lars Kruger, Annabel L. Olsen Hedemyr, Aiping Cheng, Tomas Hansson, Rayomand J. Unwalla, Christopher P. Miller, Patrik P. Rhönnstad
-
Publication number: 20090233979Abstract: The invention provides compounds of formula (I) or pharmaceutically acceptable esters, amides, solvates or salts thereof, including salts of such esters or amides, and solvates of such esters, amides or salts, (I) wherein R1, R2, R3, R4, R5, R6, Y and W are as defined in the specification. The invention also provides the use of such compounds in the treatment or prophylaxis of a condition that may be treated with a thyroid receptor agonist or partial agonist.Type: ApplicationFiled: May 24, 2007Publication date: September 17, 2009Applicant: KARO BIO ABInventors: Ana Maria Garcia Collazo, Eva Kristina Koch, Lars Johan Malm, Aiping Cheng, Tomas Fredrik Hansson
-
Publication number: 20060030612Abstract: This invention provides compounds of Formula (I) or (Ia): that are useful in the treatment or inhibition of LXR mediated diseases.Type: ApplicationFiled: August 1, 2005Publication date: February 9, 2006Applicant: WyethInventors: Robert Steffan, Edward Matelan, Stephen Bowen, John Ullrich, Jay Wrobel, Edouard Zamaratski, Lars Kruger, Annabel Hedemyr, Aiping Cheng, Tomas Hansson, Rayomand Unwalla, Christopher Miller, Patrik Rhonnstad
-
Publication number: 20040082642Abstract: The present invention relates to compounds of formula (I) and derivatives thereof, in which the variables are as defined in the claims, their synthesis, and their use as estrogen receptor modulators. The compounds of the instant invention are ligands for estrogen receptors and as such may be useful for treatment or prevention of a variety of conditions related to estrogen functioning including bone loss, bone fractures, osteoporosis, cartilage degeneration, endometriosis, uterine fibroid disease, hot flashes, increased levels of LDL cholesterol, cardiovascular disease, impairment of cognitive functioning, cerebral degenerative disorders, restinosis, gynecomastia, autoimmune disease, vascular smooth muscle cell profileration, obesity, incontinence, and cancer of the lung, colon, breast, uterus, and prostate.Type: ApplicationFiled: November 14, 2003Publication date: April 29, 2004Inventors: Konrad Koehler, Mikael Gillner, Ye Liu, Aiping Cheng, James V Heck, Milton Lloyd Hammond, Ralph Troy Mosley, Mahmoud Rahimi-Ghadim