Patents by Inventor Aiping Zhu

Aiping Zhu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Micro-structured and nano-structured surfaces on biodegradable polymers
    Patent number: 8906282
    Abstract: In embodiments of the present invention, a biodegradable/biodegradable polymer film may be used as a scaffold for tissue engineering scaffolds for engineering organized organs, such as vascular grafts, for example. In one embodiment, an ultraviolet (UV) resin made from a diacrylated biodegradable oligomer is molded into a flexible scaffold having cavities and/or channels. Channel/cavity size may be on the order of micrometers and/or nanometers, and thus the walls may have high aspect ratios. Smooth muscle cells may be deposited in the channels and because of the high aspect ratios, the cells may align along the channels/cavities as confluence is reached.
    Type: Grant
    Filed: July 6, 2005
    Date of Patent: December 9, 2014
    Assignee: Nanyang Technological University
    Inventors: Bee Eng Mary Chan, Jinye Shen, Bin He, Aiping Zhu, Yehai Yan, Chee Yoon Yue
  • RAD9 AS A DIAGNOSTIC, PROGNOSTIC AND THERAPEUTIC TOOL FOR PROSTATE CANCER
    Publication number: 20120028260
    Abstract: This disclosure provides a method of treating a human subject having a cancer which comprises administering to the subject a nucleic acid so as to inhibit expression of human RAD9 protein in a cell of the cancer so as to thereby treat the human subject. This disclosure also provides methods of assessing gains in prostate cancer therapy and detecting prostate cancer.
    Type: Application
    Filed: August 29, 2011
    Publication date: February 2, 2012
    Inventors: Howard B. Lieberman, Aiping Zhu
  • RAD 9 AS A DIAGNOSTIC,PROGNOSTIC,AND THERAPEUTIC TOOL FOR PROSTATE CANCER
    Publication number: 20100168202
    Abstract: This disclosure provides a method of treating a human subject having a cancer which comprises administering to the subject a nucleic acid so as to inhibit expression of human RAD9 protein in a cell of the cancer so as to thereby treat the human subject. This disclosure also provides methods of assessing gains in prostate cancer therapy and detecting prostate cancer.
    Type: Application
    Filed: June 6, 2008
    Publication date: July 1, 2010
    Inventors: Howard B. Lieberman, Aiping Zhu
  • Micro-structured and nano-structured surfaces on biodegradable polymers
    Publication number: 20070009572
    Abstract: In embodiments of the present invention, a biodegradable/biodegradable polymer film may be used as a scaffold for tissue engineering scaffolds for engineering organized organs, such as vascular grafts, for example. In one embodiment, an ultraviolet (UV) resin made from a diacrylated biodegradable oligomer is molded into a flexible scaffold having cavities and/or channels. Channel/cavity size may be on the order of micrometers and/or nanometers, and thus the walls may have high aspect ratios. Smooth muscle cells may be deposited in the channels and because of the high aspect ratios, the cells may align along the channels/cavities as confluence is reached.
    Type: Application
    Filed: July 6, 2005
    Publication date: January 11, 2007
    Inventors: Bee Mary Chan, Jinye Shen, Bin He, Aiping Zhu, Yehai Yan, Chee Yue