Patents by Inventor Ajit P. Joglekar

Ajit P. Joglekar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ACTIVATING MITOTIC CHECKPOINT CONTROL MECHANISMS
    Publication number: 20240043480
    Abstract: Provided herein are compositions and methods for the treatment of cancer by activating the spindle assembly checkpoint (SAC) in cells. In particular, dimerized Mps1 and Spc105/KNL1 constructs are provided as tunable activators of SAC, allowing for control of chromosome segregation accuracy and prevention of aneuploidies that are common in cancer.
    Type: Application
    Filed: February 27, 2023
    Publication date: February 8, 2024
    Inventors: Ajit P. Joglekar, Pavithra Aravamudhan
  • ACTIVATING MITOTIC CHECKPOINT CONTROL MECHANISMS
    Publication number: 20200231639
    Abstract: Provided herein are compositions and methods for the treatment of cancer by activating the spindle assembly checkpoint (SAC) in cells. In particular, dimerized Mps1 and Spc105/KNL1 constructs are provided as tunable activators of SAC, allowing for control of chromosome segregation accuracy and prevention of aneuploidies that are common in cancer.
    Type: Application
    Filed: March 31, 2020
    Publication date: July 23, 2020
    Inventors: Ajit P. Joglekar, Pavithra Aravamudhan
  • Mps1 and KNL1 phosphorylation system
    Patent number: 10669320
    Abstract: Provided herein are compositions and methods for the treatment of cancer by activating the spindle assembly checkpoint (SAC) in cells. In particular, dimerized Mps1 and Spc105/KNL1 constructs are provided as tunable activators of SAC, allowing for control of chromosome segregation accuracy and prevention of aneuploidies that are common in cancer.
    Type: Grant
    Filed: November 18, 2016
    Date of Patent: June 2, 2020
    Assignee: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
    Inventors: Ajit P. Joglekar, Pavithra Aravamudhan
  • ACTIVATING MITOTIC CHECKPOINT CONTROL MECHANISMS
    Publication number: 20170137478
    Abstract: Provided herein are compositions and methods for the treatment of cancer by activating the spindle assembly checkpoint (SAC) in cells. In particular, dimerized Mps1 and Spc105/KNL1 constructs are provided as tunable activators of SAC, allowing for control of chromosome segregation accuracy and prevention of aneuploidies that are common in cancer.
    Type: Application
    Filed: November 18, 2016
    Publication date: May 18, 2017
    Inventors: Ajit P. Joglekar, Pavithra Aravamudhan
  • Method for forming nanoscale features
    Patent number: 7560658
    Abstract: Here is presented a versatile technique for machining of nanometer-scale features using tightly-focused ultrashort laser pulses. By the invention, the size of features can be reduced far below the wavelength of light, thus enabling nanomachining of a wide range of materials. The features may be extremely small (<20 nm) and are highly reproducible.
    Type: Grant
    Filed: June 27, 2005
    Date of Patent: July 14, 2009
    Assignee: The Regents Of The University Of Michigan
    Inventors: Alan J. Hunt, Gerald Mourou, Ajit P. Joglekar, Edgar Meyhofer, John A. Nees, Greg Spooner
  • Method for forming nanoscale features
    Patent number: 6995336
    Abstract: Here is presented a versatile technique for machining of nanometer-scale features using tightly-focused ultrashort laser pulses. By the invention, the size of features can be reduced far below the wavelength of light, thus enabling nanomachining of a wide range of materials. The features may be extremely small (<20 nm) and are highly reproducible.
    Type: Grant
    Filed: January 26, 2004
    Date of Patent: February 7, 2006
    Assignee: The Regents of the University of Michigan
    Inventors: Alan J. Hunt, Gerard Mourou, Ajit P. Joglekar, Edgar Meyhofer, John A. Nees, Greg Spooner
  • Method for forming nanoscale features
    Publication number: 20040155017
    Abstract: Here is presented a versatile technique for machining of nanometer-scale features using tightly-focused ultrashort laser pulses. By the invention, the size of features can be reduced far below the wavelength of light, thus enabling nanomachining of a wide range of materials. The features may be extremely small (<20 nm) and are highly reproducible.
    Type: Application
    Filed: January 26, 2004
    Publication date: August 12, 2004
    Inventors: Alan J. Hunt, Gerard Mourou, Ajit P. Joglekar, Edgar Meyhofer, John A. Nees, Greg Spooner