Patents by Inventor Akemi YAMAGUCHI
Akemi YAMAGUCHI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20170349935Abstract: A biochip; a liquid which has a different specific gravity from that of the reaction mixture and is immiscible with the reaction mixture; and an additive containing, as a principal component, a carbinol-modified silicone resin, a carboxyl-modified silicone resin, an amino-modified silicone resin, a polyether-modified silicone resin, a silanol-modified silicone resin, or a fluoro-modified silicone resin, wherein the vessel comprising, a flow channel that is capable of flowing a liquid droplet of a reaction mixture containing a surfactant in the longitudinal direction of the vessel.Type: ApplicationFiled: August 23, 2017Publication date: December 7, 2017Inventor: Akemi YAMAGUCHI
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Patent number: 9427738Abstract: A thermal cycler includes an attachment unit having an insertion opening for insertion of a reaction container including a channel filled with a reaction solution containing reverse transcriptase enzyme and a liquid having a lower specific gravity than that of the reaction solution and being immiscible with the reaction solution, a first heating unit that heats a first region of the channel, a second heating unit that heats a second region of the channel nearer the insertion opening than the first region, a drive mechanism that switches arrangement of the attachment unit, the first heating unit, and the second heating unit between a first arrangement and a second arrangement, and a control unit that controls the first heating unit to be at a temperature at which reverse transcription reaction progresses and the second heating unit to be at a temperature at which the reverse transcriptase enzyme is not deactivated.Type: GrantFiled: March 12, 2013Date of Patent: August 30, 2016Assignee: Seiko Epson CorporationInventor: Akemi Yamaguchi
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Publication number: 20160145675Abstract: A nucleic acid amplification reaction apparatus includes: a fitting section capable of fitting a reaction vessel filled with a reaction mixture and a liquid which has a specific gravity different from that of the reaction mixture and is immiscible with the reaction mixture; a first heating section which heats a first region of the reaction vessel; a second heating section which heats a second region of the reaction vessel; and a driving mechanism which switches over between a first arrangement in which the first region is located lower than the second region in the direction of the gravitational force and a second arrangement in which the second region is located lower than the first region in the direction of the gravitational force, wherein the concentration of magnesium ions in the reaction mixture is 1.8 mM or more and 9.0 mM or less.Type: ApplicationFiled: November 18, 2015Publication date: May 26, 2016Inventors: Masayuki UEHARA, Kotaro IDEGAMI, Masato HANAMURA, Yuji SAITO, Akemi YAMAGUCHI
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Publication number: 20160121332Abstract: A nucleic acid amplification reaction apparatus includes: a fitting section capable of fitting a nucleic acid amplification reaction vessel comprising a nucleic acid amplification reaction mixture; temperature adjustment sections which adjust the temperatures of first and second regions of the nucleic acid amplification reaction vessel, respectively; and a driving mechanism which switches the location of the first and second regions; the nucleic acid amplification reaction mixture includes first and second primer pairs, the reaction apparatus performs a thermal cycle by setting the temperatures of the first and second regions to a first temperature and a second temperature, respectively, and thereafter performs a thermal cycle by setting the temperatures of the first and second regions to a third temperature and a fourth temperature, respectively.Type: ApplicationFiled: October 29, 2015Publication date: May 5, 2016Inventor: Akemi YAMAGUCHI
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Patent number: 9278356Abstract: An attachment unit for attachment of a reaction container including a channel filled with a reaction solution containing a fluorescent probe and a liquid having a specific gravity different from that of the reaction solution and being immiscible with the reaction solution, the reaction solution moving close to opposed inner walls, a first heating unit heating a first region of the channel and a second heating unit heating a second region of the channel when the reaction container is attached to the attachment unit, a drive mechanism switching arrangement of the attachment unit, the first heating unit, and the second heating unit between a first arrangement and a second arrangement in which a lowermost position of the channel is located within a first region and a second region, respectively, a measurement unit measuring light intensity, and a control unit controlling the portions described above.Type: GrantFiled: March 12, 2013Date of Patent: March 8, 2016Assignee: Seiko Epson CorporationInventors: Akemi Yamaguchi, Hiroshi Koeda
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Publication number: 20150275272Abstract: A biochip; a liquid which has a different specific gravity from that of the reaction mixture and is immiscible with the reaction mixture; and an additive containing, as a principal component, a carbinol-modified silicone resin, a carboxyl-modified silicone resin, an amino-modified silicone resin, a polyether-modified silicone resin, a silanol-modified silicone resin, or a fluoro-modified silicone resin, wherein the vessel comprising, a flow channel that is capable of flowing a liquid droplet of a reaction mixture containing a surfactant in the longitudinal direction of the vessel.Type: ApplicationFiled: March 26, 2015Publication date: October 1, 2015Inventor: Akemi YAMAGUCHI
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Publication number: 20150246355Abstract: A thermal cycler includes an attachment unit having an insertion opening for insertion of a reaction container including a channel filled with a reaction solution containing reverse transcriptase enzyme and a liquid having a lower specific gravity than that of the reaction solution and being immiscible with the reaction solution, a first heating unit that heats a first region of the channel, a second heating unit that heats a second region of the channel nearer the insertion opening than the first region, a drive mechanism that switches arrangement of the attachment unit, the first heating unit, and the second heating unit between a first arrangement and a second arrangement, and a control unit that controls the first heating unit to be at a temperature at which reverse transcription reaction progresses and the second heating unit to be at a temperature at which the reverse transcriptase enzyme is not deactivated.Type: ApplicationFiled: May 19, 2015Publication date: September 3, 2015Inventor: Akemi YAMAGUCHI
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Publication number: 20150087026Abstract: An attachment unit for attachment of a reaction container including a channel filled with a reaction solution and a liquid having a specific gravity different from that of the reaction solution and being immiscible with the reaction solution, the reaction solution moving close to opposed inner walls, a first heating unit that heats a first region of the channel and a second heating unit that heats a second region of the channel when the reaction container is attached to the attachment unit, a drive mechanism that switches arrangement of the attachment unit, the first heating unit, and the second heating unit between a first arrangement and a second arrangement in which a lowermost position of the channel is located within a first region and a second region, respectively, and a control unit that controls the drive mechanism, the first heating unit, and the second heating unit are provided.Type: ApplicationFiled: December 8, 2014Publication date: March 26, 2015Inventors: Akemi YAMAGUCHI, Hiroshi KOEDA
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Patent number: 8932833Abstract: An attachment unit for attachment of a reaction container including a channel filled with a reaction solution and a liquid having a specific gravity different from that of the reaction solution and being immiscible with the reaction solution, the reaction solution moving close to opposed inner walls, a first heating unit that heats a first region of the channel and a second heating unit that heats a second region of the channel when the reaction container is attached to the attachment unit, a drive mechanism that switches arrangement of the attachment unit, the first heating unit, and the second heating unit between a first arrangement and a second arrangement in which a lowermost position of the channel is located within a first region and a second region, respectively, and a control unit that controls the drive mechanism, the first heating unit, and the second heating unit are provided.Type: GrantFiled: March 12, 2013Date of Patent: January 13, 2015Assignee: Seiko Epson CorporationInventors: Akemi Yamaguchi, Hiroshi Koeda
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Publication number: 20130260383Abstract: An attachment unit for attachment of a reaction container including a channel filled with a reaction solution containing a fluorescent probe and a liquid having a specific gravity different from that of the reaction solution and being immiscible with the reaction solution, the reaction solution moving close to opposed inner walls, a first heating unit heating a first region of the channel and a second heating unit heating a second region of the channel when the reaction container is attached to the attachment unit, a drive mechanism switching arrangement of the attachment unit, the first heating unit, and the second heating unit between a first arrangement and a second arrangement in which a lowermost position of the channel is located within a first region and a second region, respectively, a measurement unit measuring light intensity, and a control unit controlling the portions described above.Type: ApplicationFiled: March 12, 2013Publication date: October 3, 2013Applicant: SEIKO EPSON CORPORATIONInventors: Akemi YAMAGUCHI, Hiroshi KOEDA
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Publication number: 20130260421Abstract: An attachment unit for attachment of a reaction container including a channel filled with a reaction solution and a liquid having a specific gravity different from that of the reaction solution and being immiscible with the reaction solution, the reaction solution moving close to opposed inner walls, a first heating unit that heats a first region of the channel and a second heating unit that heats a second region of the channel when the reaction container is attached to the attachment unit, a drive mechanism that switches arrangement of the attachment unit, the first heating unit, and the second heating unit between a first arrangement and a second arrangement in which a lowermost position of the channel is located within a first region and a second region, respectively, and a control unit that controls the drive mechanism, the first heating unit, and the second heating unit are provided.Type: ApplicationFiled: March 12, 2013Publication date: October 3, 2013Applicant: SEIKO EPSON CORPORATIONInventors: Akemi YAMAGUCHI, Hiroshi KOEDA
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Publication number: 20130260449Abstract: A thermal cycler includes an attachment unit having an insertion opening for insertion of a reaction container including a channel filled with a reaction solution containing reverse transcriptase enzyme and a liquid having a lower specific gravity than that of the reaction solution and being immiscible with the reaction solution, a first heating unit that heats a first region of the channel, a second heating unit that heats a second region of the channel nearer the insertion opening than the first region, a drive mechanism that switches arrangement of the attachment unit, the first heating unit, and the second heating unit between a first arrangement and a second arrangement, and the control unit performs the first heating unit to be a temperature at which reverse transcription reaction progresses and the second heating unit to be a temperature at which the reverse transcriptase enzyme is not deactivated.Type: ApplicationFiled: March 12, 2013Publication date: October 3, 2013Applicant: SEIKO EPSON CORPORATIONInventor: Akemi YAMAGUCHI