Patents by Inventor Akihiko Saito

Akihiko Saito has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20170002748
    Abstract: A gas turbine drives a power generator by rotating a turbine using combustion gas generated in a combustor as a result of supplying the combustor with fuel and compressed air from a compressor, which is provided with an inlet guide vane at a front stage. An operation control device of the gas turbine enables an IGV priority open flag when the inlet guide vane is not fully open and when the system frequency is lower than or equal to a predetermined threshold value a or there is a request for increasing the output of the gas turbine. When the IGV priority open flag is enabled, the operation control device sets the degree of opening of the inlet guide vane to be larger than before. Accordingly, the output can be increased without having to increase the turbine inlet temperature, regardless of the operational state of the gas turbine.
    Type: Application
    Filed: February 4, 2015
    Publication date: January 5, 2017
    Applicant: MITSUBISHI HITACHI POWER SYSTEMS, LTD.
    Inventors: Takashi SONODA, Kazuya HIGASHI, Akihiko SAITO
  • Publication number: 20160324813
    Abstract: The present invention includes cilastatin or a pharmaceutically acceptable salt thereof as an active component and a suppressant for renal impairment or inner ear disorders, induced via megalin by at least one megalin ligand which is selected from the group consisting of polymyxins, aminoglycoside antibiotics, glycopeptide antibiotics, cisplatin, and pharmaceutically acceptable salts thereof
    Type: Application
    Filed: July 21, 2016
    Publication date: November 10, 2016
    Applicants: EA Pharma Co., Ltd., Niigata University
    Inventors: Akihiko SAITO, Nobumasa AOKI, Yoshihisa HORI, Shoji KUWAHARA, Michihiro HOSOJIMA, Hiroshi IWATA, Saori MATSUDA
  • Publication number: 20160326967
    Abstract: A fuel control device includes a combustion temperature estimation value calculation unit that calculates a temperature estimation value when a mixture of fuel and inflow air is burned using an atmospheric condition, an opening degree command value of a valve that controls the amount of air that is mixed with the fuel and burned, and an output prediction value calculated on the basis of a fuel control signal command value used for calculation of a total fuel flow rate flowing through a plurality of fuel supply systems, a fuel distribution command value calculation unit that calculates a fuel distribution command value indicating a distribution of fuel output from the fuel supply systems based on the temperature estimation value, and outputs the fuel distribution command value, and a valve opening degree calculation unit that calculates each valve opening degree of a fuel flow rate control valve of the fuel supply systems.
    Type: Application
    Filed: February 16, 2015
    Publication date: November 10, 2016
    Applicant: MITSUBISHI HITACHI POWER SYSTEMS, LTD.
    Inventors: Keisuke YAMAMOTO, Takashi SONODA, Akihiko SAITO, Fuminori FUJII, Hisashi NAKAHARA, Ryoichi HAGA, Ryuji TAKENAKA, Yoshifumi IWASAKI, Wataru AKIZUKI, Isamu MATSUMI, Naohiro SUMIMURA, Shinichi YOSHIOKA
  • Publication number: 20160237910
    Abstract: A temperature control device includes a temperature difference calculation unit that calculates a temperature difference between an inlet and an outlet of a boost compressor on the basis of a pressure ratio of the inlet and the outlet of the boost compressor and an IGV opening degree of the boost compressor, the boost compressor outputting cooling air obtained by cooling compressed air from a compressor to a cooling target; a temperature information calculation unit that calculates temperature information for feedback control for at least one of the inlet and the outlet of the boost compressor on the basis of the temperature difference between the inlet and the outlet of the boost compressor; and a control unit that performs feedback control by using the temperature information for feedback control such that at least one of an inlet temperature and an outlet temperature of the boost compressor approaches a setting value.
    Type: Application
    Filed: October 21, 2014
    Publication date: August 18, 2016
    Inventors: Akihiko Saito, Takashi Sonoda, Tetsuya Yabe, Satoko Fujii, Kazuya Higashi
  • Publication number: 20160219726
    Abstract: A display apparatus including: a display panel; and a chassis structure which holds the display panel, wherein the chassis structure includes a first chassis member in which a recess whose opening opens toward a display panel side is formed, and a second chassis member which is in a plate shape, and mounted on the first chassis member, covering at least a portion of the opening of the recess.
    Type: Application
    Filed: April 16, 2014
    Publication date: July 28, 2016
    Applicant: JOLED INC.
    Inventors: Akihiko SAITO, Yoshihiro TANIGUCHI
  • Publication number: 20140230449
    Abstract: A valve control device is provided in a gas turbine having a combustor for generating combustion gas, a turbine driven by the combustion gas generated by the combustor, a flow rate regulating valve for regulating the flow rate of the fuel to be supplied to the combustor, and a pressure regulating valve disposed upstream of the flow rate regulating valve, for regulating the fuel pressure. The valve control device controls the opening degree of the valve. The valve control device includes a load decrease detection part which detects a load decrease of the gas turbine, and a pressure control part which controls the opening degree of the valve in accordance with the output of the gas turbine. The valve control device suppresses instability of the gas turbine output even when the load rapidly decreases.
    Type: Application
    Filed: November 22, 2012
    Publication date: August 21, 2014
    Applicant: Mitsubishi Hitachi Power Systems, Ltd.
    Inventors: Akihiko Saito, Takashi Sonoda, Takafumi Uda, Fuminori Fujii
  • Patent number: 8800296
    Abstract: An object is to reduce a fluctuation in the gas-turbine output in a nozzle switching period. In the nozzle switching period during which a first nozzle group that has been used is switched to a second nozzle group that is going to be used, the amounts of fuel supplied through the first nozzle group and the second nozzle group are adjusted by using at least one adjustment parameter registered in advance, the adjustment parameter registered in advance is updated according to the operating condition of the gas turbine, and the updated adjustment parameter is registered as an adjustment parameter to be used next.
    Type: Grant
    Filed: December 11, 2008
    Date of Patent: August 12, 2014
    Assignee: Mitsubishi Heavy Industries, Ltd.
    Inventors: Makoto Kishi, Akihiko Saito, Takashi Sonoda, Shinsuke Nakamura, Sosuke Nakamura
  • Publication number: 20140190176
    Abstract: A fuel control method for a gas turbine with a combustor being formed of at least two groups of a pluralities of main nozzles for supplying fuel, and that supplies fuel from the main nozzles of all groups upon ignition of the combustor (S1), and supplies fuel from three main nozzles of a group A during subsequent acceleration of the gas turbine (S3). Because fuel is injected from a small number of the main nozzles during acceleration, the fuel flow rate per one main nozzle is increased, thereby increasing the fuel-air ratio (fuel flow rate/air flow rate) in a combustion region and improving the combustion characteristics. Accordingly, the generation of carbon monoxide and unburned hydrocarbon is reduced, whereby no bypass valve is required and manufacturing costs are reduced.
    Type: Application
    Filed: March 10, 2014
    Publication date: July 10, 2014
    Applicant: MITSUBISHI HEAVY INDUSTRIES, LTD.
    Inventors: Sosuke NAKAMURA, Satoshi TANIMURA, Shinji AKAMATSU, Shinsuke NAKAMURA, Takashi SONODA, Akihiko SAITO, Makoto KISHI
  • Patent number: 8765124
    Abstract: Protein formulations containing a poloxamer as a surfactant, and methods for maintaining the biological activity in protein formulations without adding an antioxidant and for inhibiting the formation of foreign insoluble matters by adding a poloxamer as a surfactant.
    Type: Grant
    Filed: February 27, 2004
    Date of Patent: July 1, 2014
    Assignee: Chugai Seiyaku Kabushiki Kaisha
    Inventors: Akihiko Saito, Eiichi Miyauchi
  • Patent number: 8707671
    Abstract: A fuel control method for a gas turbine with a combustor being formed of at least two groups of a pluralities of main nozzles for supplying fuel, and that supplies fuel from the main nozzles of all groups upon ignition of the combustor (S1), and supplies fuel from three main nozzles of a group A during subsequent acceleration of the gas turbine (S3). Because fuel is injected from a small number of the main nozzles during acceleration, the fuel flow rate per one main nozzle is increased, thereby increasing the fuel-air ratio (fuel flow rate/air flow rate) in a combustion region and improving the combustion characteristics. Accordingly, the generation of carbon monoxide and unburned hydrocarbon is reduced, whereby no bypass valve is required and manufacturing costs are reduced.
    Type: Grant
    Filed: July 1, 2009
    Date of Patent: April 29, 2014
    Assignee: Mitsubishi Heavy Industries, Ltd.
    Inventors: Sosuke Nakamura, Satoshi Tanimura, Shinji Akamatsu, Shinsuke Nakamura, Takashi Sonoda, Akihiko Saito, Makoto Kishi
  • Patent number: 8703430
    Abstract: This invention provides a method for measuring human megalin that can be performed in a simpler manner within a shorter period of time than is possible with conventional techniques, and that can also quantify human megalin. This invention also provides a method that enables diagnosis of functional diseases, which are specific to cells, tissues, or organs, in a site-directed manner at an early stage. Measurement of human megalin enables detection of a disease in an organ in which megalin expression is observed.
    Type: Grant
    Filed: April 26, 2011
    Date of Patent: April 22, 2014
    Assignees: Niigata University, Denka Seiken Co., Ltd.
    Inventors: Shinya Ogasawara, Shuhei Miura, Akihiko Saito, Tetsuro Takeda
  • Patent number: 8694170
    Abstract: Provided is a gas turbine operation control device and operation control method that are capable of suppressing turbine inlet temperature and of satisfying the demand response for shaft output. An IGV emergency fully-open flag is activated when the output of a generator is in a high load band at or above a predetermined value, and the like. When the IGV emergency fully-open flag is activated, the degree of opening of an inlet guide vane is set to a predetermined degree of opening, a temperature adjustment setting is set by switching in accordance with the degree of opening of the inlet guide vane, and an exhaust gas temperature setting value or a blade path temperature setting value of a turbine, for controlling the fuel supply amount for a combustor, is generated based on the temperature adjustment setting.
    Type: Grant
    Filed: November 6, 2008
    Date of Patent: April 8, 2014
    Assignee: Mitsubishi Heavy Industries, Ltd.
    Inventors: Takashi Sonoda, Akihiko Saito, Shinsuke Nakamura
  • Patent number: 8663931
    Abstract: This invention provides a diagnostic kit and a diagnostic marker used for diagnosing a renal disease. This invention also provides a method for detecting a renal disease comprising measuring at least one type of human megalin existing in urine selected from among full-length human megalin and human megalin fragments of (i) to (iii): (i) full-length human megalin; (ii) a human megalin endodomain fragment lacking a human megalin ectodomain; and (iii) a human megalin ectodomain fragment lacking a human megalin endodomain.
    Type: Grant
    Filed: April 27, 2010
    Date of Patent: March 4, 2014
    Assignees: Niigata University, Juntendo Educational Foundation, Denka Seiken Co., Ltd.
    Inventors: Akihiko Saito, Yasuhiko Tomino, Katsuhiko Asanuma, Shinya Ogasawara, Hiroyuki Kurosawa, Yoshiaki Hirayama
  • Patent number: 8628930
    Abstract: This invention provides a simple means for detecting a renal disorder, a diagnostic marker for a renal disorder that enables prognostic prediction of a renal disorder (e.g., diabetic nephropathy and IgA nephropathy) and evaluation of the degree of nephropathy at the phase of stage-II diabetic nephropathy by measuring the megalin level in urine associated with a renal disorder used for the detection means, and use of such marker. The invention also provides the use of human megalin obtained from the urine sample of a subject as a marker for detecting a renal disorder.
    Type: Grant
    Filed: April 27, 2010
    Date of Patent: January 14, 2014
    Assignees: Niigata University, Juntendo Education Foundation, Denka Seiken Co., Ltd.
    Inventors: Akihiko Saito, Yasuhiko Tomino, Katsuhiko Asanuma, Shinya Ogasawara, Hiroyuki Kurosawa, Yoshiaki Hirayama
  • Publication number: 20120164667
    Abstract: Provided is a test method for the detection of diabetic nephropathy at an early stage as compared to a conventional method. Specifically provided are: a test method for diabetic nephropathy, including detecting urinary podocalyxin; the test method, further including assessing diabetic nephropathy at least Stage I; a test reagent for use in the test method; and a test reagent kit for use in the test method. The present invention is based on a finding that urinary podocalyxin reflects the development and condition of diabetic nephropathy with high sensitivity at an early stage as compared to urinary albumin.
    Type: Application
    Filed: June 9, 2010
    Publication date: June 28, 2012
    Applicants: DENKA SEIKEN CO., LTD., JUNTENDO EDUCATIONAL FOUNDATION, NIIGATA UNIVERSITY
    Inventors: Masanori Hara, Akihiko Saito, Yasuhiko Tomino, Katsuhiko Asanuma, Hiroyuki Kurosawa, Shinya Ogasawara, Yoshiaki Hirayama
  • Publication number: 20120164662
    Abstract: Provided is a test method for the assessment of the necessity of renal biopsy in a subject to be tested, who is suspected of having a renal disease. Specifically provided are a test method for a renal disease, including using urinary podocalyxin and one or more additional markers in combination, and a test reagent for use in the test method and a test reagent kit for use in the test method. The present invention allows the discrimination of a poor prognosis group even for poor prognosis cases with no overt findings in a conventional test method, and thus allows the assessment of a renal disease, the assessment of the necessity of renal biopsy, prognostic prediction, and the like to be performed exactly.
    Type: Application
    Filed: June 9, 2010
    Publication date: June 28, 2012
    Applicants: DENKA SEIKEN CO., LTD, JUNTENDO EDUCATIONAL FOUNDATION, NIIGATA UNIVERSITY
    Inventors: Masanori Hara, Akihiko Saito, Yasuhiko Tomino, Katsuhiko Asanuma, Hiroyuki Kurosawa, Shinya Ogasawara, Yoshiaki Hirayama
  • Publication number: 20120058489
    Abstract: This invention provides a simple means for detecting a renal disorder, a diagnostic marker for a renal disorder that enables prognostic prediction of a renal disorder (e.g., diabetic nephropathy and IgA nephropathy) and evaluation of the degree of nephropathy at the phase of stage-II diabetic nephropathy by measuring the megalin level in urine associated with a renal disorder used for the detection means, and use of such marker. The invention also provides the use of human megalin obtained from the urine sample of a subject as a marker for detecting a renal disorder.
    Type: Application
    Filed: April 27, 2010
    Publication date: March 8, 2012
    Inventors: Akihiko Saito, Yasuhiko Tomino, Katsuhiko Asanuma, Shinya Ogaswara, Hiroyuki Kurosawa, Yoshiaki Hirayama
  • Publication number: 20120040374
    Abstract: This invention provides a diagnostic kit and a diagnostic marker used for diagnosing a renal disease. This invention also provides a method for detecting a renal disease comprising measuring at least one type of human megalin existing in urine selected from among full-length human megalin and human megalin fragments of (i) to (iii): (i) full-length human megalin; (ii) a human megalin endodomain fragment lacking a human megalin ectodomain; and (iii) a human megalin ectodomain fragment lacking a human megalin endodomain.
    Type: Application
    Filed: April 27, 2010
    Publication date: February 16, 2012
    Inventors: Akihiko Saito, Yasuhiko Tomino, Katsuhiko Asanuma, Shinya Ogasawara, Hiroyuki Kurosawa, Yoshiaki Hirayama
  • Patent number: 8105840
    Abstract: Described are a urine pretreatment agent, a urine pretreatment method, and a urinary protein quantitation method which reduce or cancel the influences of urine pH variations, cancel the influences of precipitates of urinary inorganic salts, and solubilize membrane proteins. The urine pretreatment agent for urinary protein quantitation, includes a buffer, a chelating agent, and a surfactant; the urine pretreatment method includes a step of mixing 10 to 1000 parts by mass of the urine pretreatment agent of the present invention with 100 parts by mass of urine; and the urinary protein quantitation method includes steps of: mixing 10 to 1000 parts by mass of the urine pretreatment agent with 100 parts by mass of urine; and then measuring the protein concentration.
    Type: Grant
    Filed: September 26, 2008
    Date of Patent: January 31, 2012
    Assignees: Niigata University, Denka Seiken Co., Ltd.
    Inventors: Masanori Hara, Akihiko Saito, Shinya Ogasawara, Yoshiaki Hirayama, Hiroyuki Kurosawa
  • Patent number: 7997084
    Abstract: A gasifying furnace gasifies solid fuel or liquid fuel. A gas turbine drives a turbine to generate power by using combustion gas generated by burning mixed gas of compressed air compressed in a compressor and gas generated in the gasifying furnace in a combustor. A booster boosts compressed air bled from the compressor, and feed the compressed air to the gasifying furnace. A bleed source valve is provided in a bleed line between the compressor and the booster. An abnormality stop controller stops the booster and the gas turbine, based on an opening angle of the bleed source valve or a bleed pressure on an upstream side of the bleed source valve.
    Type: Grant
    Filed: December 14, 2006
    Date of Patent: August 16, 2011
    Assignee: Mitsubishi Heavy Industries, Ltd.
    Inventors: Satoru Kamohara, Akihiko Saito, Takashi Sonada, Yasuhiro Takashima, Satoko Fujii