Patents by Inventor Akiko Nakatani

Akiko Nakatani has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20140121864
    Abstract: A presence notification system generates a notification sound around a vehicle with a quiet running sound, such as a hybrid car, an electric automobile, or a fuel-cell automobile, and notifies pedestrians of presence and approaching of the vehicle so as to be capable of heightening safety, and can maintain comfortability in the vehicle without bringing discomfort to the surrounding pedestrians and a driver and a fellow passenger in the vehicle. A contact pickup device 3 for capturing oscillation of a housing of an inverter I so as to convert the oscillation into an electric signal is mounted to the housing of the inverter I to be used in a driving circuit for driving an electric motor M. An amplifying device 5 for amplifying the electric signal output from the contact pickup device 3 is provided, and a notification sound generating device 2 for outputting a sound to a periphery of the vehicle based on the electric signal output from the amplifying device 5 is provided.
    Type: Application
    Filed: October 25, 2012
    Publication date: May 1, 2014
    Inventor: Akiko NAKATANI
  • Publication number: 20130281476
    Abstract: The present invention relates to modulators of muscarinic receptors. The present invention also provides compositions comprising such modulators, and methods therewith for treating muscarinic receptor mediated diseases.
    Type: Application
    Filed: June 17, 2013
    Publication date: October 24, 2013
    Inventors: Lewis R. Makings, Miguel Garcia-Guzman Blanco, Dennis J. Hurley, Ioana Drutu, Gabriel Raffai, Daniele M. Bergeron, Akiko Nakatani, Andreas P. Termin, Alina Silina
  • Patent number: 8497295
    Abstract: The present invention relates to modulators of muscarinic receptors. The present invention also provides compositions comprising such modulators, and methods therewith for treating muscarinic receptor mediated diseases.
    Type: Grant
    Filed: July 11, 2012
    Date of Patent: July 30, 2013
    Assignee: Vertex Pharmaceuticals Incorporated
    Inventors: Lewis R. Makings, Miguel Garcia-Guzman Blanco, Dennis J. Hurley, Ioana Drutu, Gabriel Raffai, Daniele M. Bergeron, Akiko Nakatani, Andreas P. Termin, Alina Silina
  • Publication number: 20130180033
    Abstract: A headset for a helmet transmits audio signals using bone conduction, and transmits audio signals even when not using bone conduction. A headset for a helmet for transmitting audio signals to a user wearing a helmet includes: a bone conduction oscillator which receives the audio signals and emits audio oscillations; an arm part which has the bone conduction oscillator on the leading end side thereof; and an attachment part which attaches the base end side of the arm part on the outer side of the crown of the helmet in a rotatable manner. The bone conduction oscillator is brought into contact with either the head portion of the user or the outer side of the crown, depending on the angle of rotation a of the arm part. The audio signals are thus transmitted to the user when bone conduction is not used by using sounds emitted by the crown.
    Type: Application
    Filed: September 26, 2011
    Publication date: July 18, 2013
    Applicants: GOLDENDANCE CO., LTD., WEST NIPPON EXPRESSWAY MAINTENANCE KANSAI CO., LTD
    Inventors: Seiji Uemoto, Akiko Nakatani
  • Patent number: 8367691
    Abstract: The present invention relates to modulators of muscarinic receptors. The present invention also provides compositions comprising such modulators, and methods therewith for treating muscarinic receptor mediated diseases.
    Type: Grant
    Filed: June 4, 2010
    Date of Patent: February 5, 2013
    Assignee: Vertex Pharmaceutical Incorporated
    Inventors: Lewis R. Makings, Miguel Garcia-Guzman Blanco, Dennis J. Hurley, Ioana Drutu, Gabriel Raffai, Daniele M. Bergeron, Akiko Nakatani, Andreas P. Termin, Alina Silina
  • Publication number: 20120283243
    Abstract: The present invention relates to modulators of muscarinic receptors. The present invention also provides compositions comprising such modulators, and methods therewith for treating muscarinic receptor mediated diseases.
    Type: Application
    Filed: July 11, 2012
    Publication date: November 8, 2012
    Applicant: Vertex Pharmaceuticals Incorporated
    Inventors: Lewis R. Makings, Miguel Garcia-Guzman Blanco, Dennis J. Hurley, Ioana Drutu, Gabriel Raffai, Daniele M. Bergeron, Akiko Nakatani, Andreas P. Termin, Alina Silina
  • Patent number: 8263605
    Abstract: The present invention relates to modulators of muscarinic receptors of formula (I). The present invention also provides impositions comprising such modulators, and methods therewith for treating muscarinic receptor mediated diseases.
    Type: Grant
    Filed: February 22, 2007
    Date of Patent: September 11, 2012
    Assignee: Vertex Pharmaceutical Incorporated
    Inventors: Lewis R. Makings, Miguel Garcia-Guzman Blanco, Dennis J. Hurley, Ioana Drutu, Gabriel Raffai, Daniele M. Bergeron, Akiko Nakatani, Andreas P. Termin, Alina Silina
  • Patent number: 8258148
    Abstract: The present invention relates to spiroindoline modulators of muscarinic receptors. The present invention also provides compositions comprising such spiroindoline modulators, and methods therewith for treating muscarinic receptor mediated diseases.
    Type: Grant
    Filed: May 24, 2010
    Date of Patent: September 4, 2012
    Assignee: Vertex Pharmaceutical Incorporated
    Inventors: Lewis R. Makings, Miguel Garcia-Guzman Blanco, Dennis J. Hurley, Ioana Drutu, Gabriel Raffai, Daniele M. Bergeron, Akiko Nakatani, Andreas P. Termin, Alina Silina
  • Patent number: 7879834
    Abstract: The present invention relates to spiroindoline modulators of muscarinic receptors. The present invention also provides compositions comprising such spiroindoline modulators, and methods therewith for treating muscarinic receptor mediated diseases.
    Type: Grant
    Filed: August 19, 2005
    Date of Patent: February 1, 2011
    Assignee: Vertex Pharmaceuticals Incorporated
    Inventors: Lewis R. Makings, Miguel Garcia-Guzman Blanco, Dennis R. Hurley, Ioana Drutu, Gabriel Raffai, Daniele J. Bergeron, Akiko Nakatani, Andreas P. Termin, Alina Silina
  • Patent number: 7880007
    Abstract: The present invention relates to modulators of muscarinic receptors. The present invention also provides compositions comprising such modulators, and methods therewith for treating muscarinic receptor mediated diseases.
    Type: Grant
    Filed: November 29, 2005
    Date of Patent: February 1, 2011
    Assignee: Vertex Pharmaceuticals Incorporated
    Inventors: Dennis J. Hurley, Daniele M. Bergeron, Ioana Drutu, Miguel Garcia-Guzman Blanco, Lewis R. Makings, Akiko Nakatani, Gabriel Raffai, Alina Silina
  • Patent number: 7863449
    Abstract: The present invention relates to modulators of muscarinic receptors. The present invention also provides compositions comprising such modulators, and methods therewith for treating muscarinic receptor mediated diseases.
    Type: Grant
    Filed: November 29, 2005
    Date of Patent: January 4, 2011
    Assignee: Vertex Pharmaceuticals Incorporated
    Inventors: Ioana Drutu, Dennis J. Hurley, Upul K. Bandarage, Daniele M. Bergeron, Paul S. Charifson, Robert J. Davies, Miguel Garcia-Guzman Blanco, Lewis R. Makings, Akiko Nakatani, Gabriel Raffai
  • Patent number: 7858635
    Abstract: The present invention relates to spiro compounds of formula XX as modulators of muscarinic receptors, wherein R1, R2, R3, Z1, Z2, L, G, n, m, t and p are defined herein. The present invention also provides compositions comprising such modulators, and methods therewith for treating muscarinic receptor mediated diseases.
    Type: Grant
    Filed: December 22, 2006
    Date of Patent: December 28, 2010
    Assignee: Vertex Pharmaceuticals Incorporated
    Inventors: Lewis R. Makings, Miguel Garcia-Guzman Blanco, Dennis J. Hurley, Ioana Drutu, Gabriel Raffai, Daniele M. Bergeron, Akiko Nakatani, Andreas P. Termin, Alina Silina
  • Publication number: 20100311746
    Abstract: The present invention relates to modulators of muscarinic receptors. The present invention also provides compositions comprising such modulators, and methods therewith for treating muscarinic receptor mediated diseases.
    Type: Application
    Filed: June 4, 2010
    Publication date: December 9, 2010
    Applicant: Vertex Pharmaceuticals Incorporated
    Inventors: Lewis R. Makings, Miguel Garcia-Guzman Blanco, Dennis J. Hurley, Ioana Drutu, Gabriel Raffai, Daniele M. Bergeron, Akiko Nakatani, Andreas P. Termin, Alina Silina
  • Publication number: 20100311720
    Abstract: The present invention relates to spiroindoline modulators of muscarinic receptors. The present invention also provides compositions comprising such spiroindoline modulators, and methods therewith for treating muscarinic receptor mediated diseases.
    Type: Application
    Filed: May 24, 2010
    Publication date: December 9, 2010
    Applicant: Vertex Pharmaceuticals Incorporated
    Inventors: Lewis R. Makings, Miguel Garcia-Guzman Blanco, Dennis J. Hurley, Ioana Drutu, Gabriel Raffai, Daniele M. Bergeron, Akiko Nakatani, Andreas P. Termin, Alina Silina
  • Patent number: 7820817
    Abstract: The present invention relates to substituted piperazine compounds that are useful modulators of muscarinic receptors. The present invention also provides compositions comprising such compounds, and methods for treating muscarinic receptor mediated diseases.
    Type: Grant
    Filed: May 31, 2005
    Date of Patent: October 26, 2010
    Assignee: Vertex Pharmaceuticals Incorporated
    Inventors: Lewis Makings, Dennis Hurley, Miguel Gracia-Guzman Blanco, Daniele Bergeron, Akiko Nakatani
  • Patent number: 7786141
    Abstract: The present invention relates to dihydrospiroindene modulators of muscarinic receptors. The present invention also provides compositions comprising such dihydrospiroindene modulators, and methods therewith for treating muscarinic receptor mediated diseases.
    Type: Grant
    Filed: February 22, 2006
    Date of Patent: August 31, 2010
    Assignee: Vertex Pharmaceuticals Incorporated
    Inventors: Lewis R. Makings, Miguel Garcia-Guzman Blanco, Dennis J. Hurley, Ioana Drutu, Gabriel Raffai, Daniele M. Bergeron, Akiko Nakatani, Andreas P. Termin, Alina Silina
  • Publication number: 20100105693
    Abstract: The present invention relates to substituted piperazine compounds that are useful modulators of muscarinic receptors. The present invention also provides compositions comprising such compounds, and methods for treating muscarinic receptor mediated diseases.
    Type: Application
    Filed: January 5, 2010
    Publication date: April 29, 2010
    Applicant: Vertex Pharmaceuticals Incorporated
    Inventors: Lewis Makings, Dennis Hurley, Miguel Gracia-Guzman Blanco, Daniele Bergeron, Akiko Nakatani
  • Publication number: 20090239873
    Abstract: The present invention relates to modulators of muscarinic receptors. The present invention also provides compositions comprising such modulators, and methods therewith for treating muscarinic receptor mediated diseases.
    Type: Application
    Filed: December 31, 2008
    Publication date: September 24, 2009
    Inventors: Miguel Garcia-Guzman Blanco, Daniele Bergeron, Peter D. J. Grootenhuis, Dennis Hurley, Akiko Nakatani, Lewis R. Makings, Daniel DiSepio, Gabriel Raffai
  • Publication number: 20090227614
    Abstract: The present invention relates to modulators of muscarnic receptors of formula (I). The present invention also provides impositions comprising such modulators, and methods therewith for treating muscarinic receptor mediated diseases.
    Type: Application
    Filed: February 22, 2007
    Publication date: September 10, 2009
    Inventors: Lewis R. Makings, Miguel Garcia-Guzman Blanco, Dennis J. Hurley, Ioana Drutu, Gabriel Raffai, Daniele M. Bergeron, Akiko Nakatani, Andreas P. Termin, Alina Silina
  • Patent number: 7563795
    Abstract: The present invention relates to modulators of muscarinic receptors. The present invention also provides compositions comprising such modulators, and methods therewith for treating muscarinic receptor mediated diseases.
    Type: Grant
    Filed: September 27, 2004
    Date of Patent: July 21, 2009
    Assignee: Vertex Pharmaceuticals Incorporated
    Inventors: Miguel Garcia-Guzman Blanco, Daniele Bergeron, Peter D. J. Grootenhuis, Dennis Hurley, Akiko Nakatani, Lewis R. Makings, Daniel DiSepio, Gabriel Raffai