Patents by Inventor Akimasa Ohmizu

Akimasa Ohmizu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Manufacturing process for the production of purified transferrin
    Patent number: 5744586
    Abstract: Method for obtaining highly purified transferrin from a partially purified plasma fraction containing transferrin in which the starting fraction is concentrated. Its ionic strength is reduced and then transferrin is adsorbed onto a chromatographic column. Following elution, the transferrin can be further processed through to packaging in final containers. The final purified transferrin product is sterile, at least 95% pure and is substantially free of enveloped and non-enveloped viruses.
    Type: Grant
    Filed: June 26, 1996
    Date of Patent: April 28, 1998
    Assignee: Alpha Therapeutic Corporation
    Inventors: John M. Rolf, Akimasa Ohmizu, Shawn D. Latham, Prabir Bhattacharya
  • Liquid preparation of antithrombin-III and stabilizing method therefor
    Patent number: 5589516
    Abstract: A liquid preparation of antithrombin-III (AT-III), comprising an AT-III and an organic acid, a salt thereof, a sugar sulfate or a surfactant as a stabilizer, and a liquid preparation of AT-III, having a pH of 9-10. The preparation of the present invention is stable after long-term preservation and poses no clinical problems in terms of pharmacological effects and safety. The preparation is more advantageous than lyophilized preparations in that it does not require dissolution in injectable distilled water and can be used easily. Accordingly, the preparation is clinically very useful.
    Type: Grant
    Filed: December 5, 1994
    Date of Patent: December 31, 1996
    Assignee: The Green Cross Corporation
    Inventors: Katsuhiro Uriyu, Akimasa Ohmizu, Hajime Fukuyama, Kazuo Takechi, Kazumasa Yokoyama
  • Process for the purification of HBsAg
    Patent number: 4694074
    Abstract: A process for the purification of HBsAg is disclosed, which comprises adsorbing specifically on a carrier, in the presence of an inorganic salt in an amount of 5 to 25 W/V %, an HBsAg obtained by gene engineering.
    Type: Grant
    Filed: October 28, 1985
    Date of Patent: September 15, 1987
    Assignee: Green Cross Corporation
    Inventors: Yahiro Uemura, Takao Ohmura, Akimasa Ohmizu, Akinori Sumi, Wataru Ohtani, Yoshitaka Sakanishi, Hiroshi Morise, Hirofumi Arimura, Tadakazu Suyama
  • Method of lyophilizing cold insoluble globulin
    Patent number: 4565651
    Abstract: A lyophylized cold insoluble globulin preparation can be prepared in stable condition and in short time by lyophylizing an aqueous solution of a cold insoluble globulin in the presence of albumin and a neutral amino acid, a monosaccharide, a disaccharide or a sugar alcohol. The preparation dissolves in water without occurrence of turbidity and is usable for injection.
    Type: Grant
    Filed: October 3, 1983
    Date of Patent: January 21, 1986
    Assignee: The Green Cross Corporation
    Inventors: Takao Ohmura, Yutaka Hirao, Takuji Hanamura, Akimasa Ohmizu, Satoshi Funakoshi
  • Process for producing a hepatitis B infection preventing vaccine
    Patent number: 4565697
    Abstract: A process for producing a hepatitis B infection preventing vaccine containing hepatitis B surface antigen as a main component thereof which comprises removing human plasma components possibly causing adverse effects and components capable of causing hepatitis B infection by incorporating steps of fractionation using ammonium sulfate, adsorption on a colloidal silicate and fractionation using polyethylene glycol into the purification stage after heat treatment and further carrying out a treatment for infectivity inactivation without causing any antigenicity impairment.
    Type: Grant
    Filed: November 15, 1983
    Date of Patent: January 21, 1986
    Assignee: Green Cross Corporation
    Inventors: Takao Ohmura, Terufumi Fujiwara, Akimasa Ohmizu, Satoshi Funakoshi