Patents by Inventor Akinori Suginaka

Akinori Suginaka has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5540935
    Abstract: A reactive vesicle comprising, as a vesicle-forming component, a reactive phospholipid derivative represented by the following general formula (1) and a functional substance-fixed vesicle prepared by reacting the reactive vesicle with a functional substance: ##STR1## in which R.sup.1 C(.dbd.O) and R.sup.2 C(.dbd.O) each represent an aliphatic acyl group, R.sup.3 denotes hydrogen atom or methyl group, OA represents an oxyalkylene group of 2-4 carbon atoms, n indicates the average number of moles of added oxyalkylene group and is 1-1,000, p is 0 or 1, X represents ##STR2## with q and r each being an integer of 0 to 4 or 1 to 4, respectively, and M denotes hydrogen atom or an alkli metal atom.
    Type: Grant
    Filed: December 5, 1994
    Date of Patent: July 30, 1996
    Assignee: NOF Corporation
    Inventors: Tsuyoshi Miyazaki, Kazuo Maruyama, Motoharu Iwatsuru, Kouzoh Sanchika, Mitsuhiro Nishida, Tohru Yasukohchi, Shigeru Kitano, Akinori Suginaka, Yoshihito Kadoma
  • Patent number: 5463066
    Abstract: A novel and useful phospholipid derivative to be used for a reactive vesicle-forming agent, which is represented by the following general formula (1): ##STR1## in which R.sup.1 C(.dbd.O) and R.sup.2 C(.dbd.O) represent each an aliphatic acyl group, R.sup.3 denotes hydrogen atom or methyl group, OA represents an oxyalkylene group of 2-4 carbon atoms, n indicates the average addition mole number of added oxyalkylene group and is 1-1,000, p is 0 or 1, X represents ##STR2## with q and r being each an integer of 0 to 4 or 1 to 4, respectively, and M denotes hydrogen atom or an alkali metal atom.
    Type: Grant
    Filed: December 5, 1994
    Date of Patent: October 31, 1995
    Assignee: NOF Corporation
    Inventors: Tsuyoshi Miyazaki, Kouzoh Sanchika, Mitsuhiro Nishida, Tohru Yasukohchi, Shigeru Kitano, Akinori Suginaka, Yoshihito Kadoma
  • Patent number: 5296355
    Abstract: A method for assaying an immunologically active substance based on the antigen-antibody reaction in a liquid phase, and a reagent for use in the method are disclosed. This method comprises adding a reagent containing a compound represented by the general formulaR.sup.1 O---[(CH.sub.2 CH.sub.2 O).sub.m (AO).sub.n ]--R.sup.2(wherein R.sup.1 and R.sup.2 each represents a hydrogen atom or a hydrocarbyl group containing 1 to 5 carbon atoms, AO represents an oxyalkylene group containing 3 to 4 carbon atoms, m and n represent the number of oxyethylene groups and that of oxyalkylene groups, respectively, with said oxyethylene groups and oxyalkylene groups forming a random copolycondensate and having a molecular weight of 1000 to 20000, and the ratio of m/n being 60/40 to 90/10).
    Type: Grant
    Filed: June 12, 1991
    Date of Patent: March 22, 1994
    Assignee: Hoeschst Aktiengesellschaft
    Inventors: Shoichi Shutoh, Akinori Suginaka, Mikio Akita
  • Patent number: 5130126
    Abstract: The present invention provides a polymer-combined drug having directional characteristics to digestive organs, wherein it comprises a medicine combined with a polymer which has an alkyleneoxy group as a repeating unit. The polymer-combined drug is produced by reacting a polyoxyalkylene glycol having one or more terminal functional groups and a medicine, if necessary in a solvent, and if necessary in the presence of a catalyst. It is able to administer the drug orally or by intravenous injection so as to maintain the concentration in blood stably for a long time, and to absorb or take in digestive organs such as the stomach and intestines directly.
    Type: Grant
    Filed: March 28, 1991
    Date of Patent: July 14, 1992
    Assignee: Nippon Oil & Fats Co., Ltd.
    Inventors: Yoshiyuki Koyama, Shuji Kojima, Tsuyoshi Miyazaki, Akinori Suginaka, Takeo Matsumoto, Yoshishige Murata
  • Patent number: 4592907
    Abstract: It is proposed a hair-rinse liquid having pearly luster, which includes the following four components A to D, namely:component A: a cationic surface active agent expressed by the general formula (I), as given below;component B: an amine oxide represented by the general formula (II), as given also in below;component C: an amino acid having an isoelectric point not higher than 7 andcomponent D: a salt of an alkali metal or alkaline earth metal. ##STR1## In the above formulae (I) and (II), R.sup.1, R.sup.2, R.sup.3 and R.sup.4 represent each a hydrocarbon group or a hydroxy alkyl group having 1-24 carbon atoms, which may be identical or different with each other, and the sum of the total carbon atoms in each formula should lie within the range of 16-45 and X denotes a halogen atom.
    Type: Grant
    Filed: March 20, 1985
    Date of Patent: June 3, 1986
    Assignee: Nippon Oil and Fats Co., Ltd.
    Inventors: Shin-ichi Akimoto, Akinori Suginaka
  • Patent number: 4462984
    Abstract: A suppository base composition comprising 5-80% by weight of polyethylene glycol, 5-80% by weight of triglyceride of fatty acid having 6-22 carbon atoms and 5-80% by weight of a specifically limited alkylene oxide derivative has a melting point of 30.degree.-60.degree. C., a compatibility with both of a polar drug component and a non-polar drug component, and can provide suppositories having excellent moldability and storage stability.
    Type: Grant
    Filed: September 27, 1982
    Date of Patent: July 31, 1984
    Assignee: Nippon Oil and Fats Company, Ltd.
    Inventors: Mitsuo Mizuno, Akinori Suginaka, Masahiko Fujii, Shinichi Akimoto
  • Patent number: 4368185
    Abstract: A suppository base composition comprising 5-80% by weight of polyethylene glycol, 5-80% by weight of triglyceride of fatty acid having 6-22 carbon atoms and 5-80% by weight of a specifically limited alkylene oxide derivative has a melting point of 30.degree.-60.degree. C., a compatibility with both of a polar drug component and a non-polar drug component, and can provide suppositories having excellent moldability and storage stability.
    Type: Grant
    Filed: October 20, 1980
    Date of Patent: January 11, 1983
    Assignee: Nippon Oil and Fats Company, Ltd.
    Inventors: Mitsuo Mizuno, Akinori Suginaka, Masahiko Fujii, Shinichi Akimoto