Abstract: The present invention is intended mainly to provide an external preparation that exerts a therapeutic and/or preventive effect against dermatological infections such as acne involving suppurative inflammation, and superficial infections of the skin upon being administered to a human patient once daily. For example, the present invention is an external preparation that comprises 1-cyclopropyl-8-methyl-7-[5-methyl-6-(methylamino)-3-pyridyl]-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid and/or a pharmaceutically acceptable salt thereof as an active ingredient, and that exerts a therapeutic and/or preventive effect against a dermatological infection upon being administered to a human patient once daily.

Abstract: The present invention is intended mainly to provide an external preparation that exerts a therapeutic and/or preventive effect against dermatological infections such as acne involving suppurative inflammation, and superficial infections of the skin upon being administered to a human patient once daily. For example, the present invention is an external preparation that comprises 1-cyclopropyl-8-methyl-7-[5-methyl-6-(methylamino)-3-pyridyl]-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid and/or a pharmaceutically acceptable salt thereof as an active ingredient, and that exerts a therapeutic and/or preventive effect against a dermatological infection upon being administered to a human patient once daily.

Abstract: There is described a pressure-responsive switch device particularly suitable for the detection of a pressure drop in a pneumatic tire on a vehicle wheel, wherein a contact carrying movable rod member is securely urged into a contact closing position by means of a conical compression spring to actuate a warning device whenever the internal pressure of the tire drops below a predetermined level. A permanent magnet may be mounted at the contact point of the switch to impart a quick motion thereto.

Abstract: A pneumatic safety tire having a pair of annular elastomeric reinforcements applied to tire carcass, each reinforcement having an intermediate portion which is located at a position corresponding to the junction of sidewall and tread. Each reinforcement extends toward both the tire equator and the corresponding one of tire beads, while gradually diminishing its thickness as it extends away from the intermediate portion. The maximum thickness of the reinforcement is 3 to 15% of the maximum tire section width under inflated condition.

Abstract: A low tire pressure alarm system for pneumatic tires, wherein a radio transmitter which is adapted to produce an alarm signal of a predetermined frequency upon detection of an abnormal pressure drop is accommodated in a hollow casing for mounting on a wheel cap casing of a vehicle wheel. The alarm signal is transmitted through the hollow casing per se or through a metal coating on the hollow casing where the latter is formed from a non-conductive material. The transmitted signal is received by a receiving set which includes a receiving antenna located on the underside of the vehicle body for shielding the same from spurious or extraneous signals and a radio receiving unit mounted within a luggage compartment of signals. Upon reception of the alarm signal, the radio receiver actuates an alarming device which produces a flashing light or sound to indicate the pressure drop to an operator of the vehicle.