Patents by Inventor Akira Kikuchi

Akira Kikuchi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240136274
    Abstract: A quantum device capable of effectively cooling a quantum chip and an area (e.g., a space) therearound is provided. A quantum device includes a quantum chip and an interposer on which the quantum chip is located. The interposer includes an interposer substrate and an interposer wiring layer. The interposer wiring layer is disposed on a surface of the interposer substrate on a side on which the quantum chip is located. The interposer wiring layer includes, in at least a part thereof, a superconducting material layer formed of a superconducting material and a non-superconducting material layer formed of a non-superconducting material.
    Type: Application
    Filed: July 26, 2023
    Publication date: April 25, 2024
    Applicant: NEC Corporation
    Inventors: Katsumi KIKUCHI, Akira MIYATA, Suguru WATANABE, Takanori NISHI, Hideyuki SATOU, Kenji NANBA, Ayami YAMAGUCHI
  • Patent number: 11942873
    Abstract: A secondary magnetic excitation generator-motor device that inputs a first ignition pulse command to a three-level NPC power converter such that a detected excitation current value corresponds with an excitation current command value, the secondary magnetic excitation generator-motor device having a function of identifying a first phase, a second phase, or a third phase in descending order of a current absolute value, wherein a pulse switch to output an ignition pulse command to the three-level NPC power converter switches the ignition pulse command to the second ignition pulse command when a current absolute value exceeds a set overcurrent level 1, and switches the ignition pulse command to the first ignition pulse command when current absolute values for three phases are all equal to or smaller than a set overcurrent level 2.
    Type: Grant
    Filed: August 8, 2019
    Date of Patent: March 26, 2024
    Assignees: HITACHI MITSUBISHI HYDRO CORPORATION, HITACHI, LTD.
    Inventors: Akira Bando, Hironari Kawazoe, Akira Kikuchi
  • Publication number: 20240069297
    Abstract: In an optical fiber cable in which an optical fiber ribbon formed by parallelly arranging a plurality of optical fibers is packaged in an internal space, a core portion of each optical fiber is made of pure quartz and an effective cross-sectional area of the core portion at a wavelength of 1,550 nm is 110 ?m2 or more and 150 ?m2 or less. The optical fiber ribbon is an optical fiber ribbon in which the optical fibers are connected by continuously applying an adhesive resin between adjacent optical fibers. An occupation ratio of the optical fiber ribbon to the internal space calculated from a ratio of a cross-sectional area of the internal space to a cross-sectional area of the packaged optical fiber ribbon is 25% or more and 55% or less.
    Type: Application
    Filed: November 10, 2021
    Publication date: February 29, 2024
    Inventors: Yutaka HASHIMOTO, Fumiaki SATO, Masashi KIKUCHI, Akira SAKURAI, Yusuke YAMADA
  • Publication number: 20240039414
    Abstract: Provided is a power conversion device that can be realized with a small circuit and is capable of stably converting AC power inputted from a three-phase power source system into DC power. In a power conversion device: an output terminal of a common converter cell in a J-numbered stage is connected, together with output terminals of common converter cells of the other two phases, to common lines; an output terminal of an independent converter cell in a K-numbered stage is connected to independent lines independently of converter cells of the other two phases; and a plurality of switches comprise a common switch for switching the connection relationship between the common lines and DC buses, and an independent switch for switching the connection relationship between the independent lines and DC buses.
    Type: Application
    Filed: May 7, 2021
    Publication date: February 1, 2024
    Inventors: Akira KIKUCHI, Akihiko KANOUDA
  • Patent number: 11807679
    Abstract: The purpose of the present invention is to provide an anti-CKAP4 monoclonal antibody that inhibits the binding of DKK1 and CKAP4 and exhibits an exceptional antitumor effect. Provided is an anti-CKAP4 monoclonal antibody that recognizes at least part of the 451-455 region, at least part of the 481-485 region, at least part of the 502-510 region, at least part of the 503-524 region and at least part of the 585-590 region, or at least part of the 585-592 region of the amino acid sequence (amino acid sequence of CKAP4) represented by SEQ ID NO:1 as an epitope, the anti-CKAP4 monoclonal antibody effectively inhibiting the binding of DKK1 and CKAP4, the activation of AKT of S2-CP8 cells, and the proliferative ability of S2-CP8 cells or the migratory ability of S2-CP8 cells, and exhibiting an exceptional antitumor effect.
    Type: Grant
    Filed: September 26, 2018
    Date of Patent: November 7, 2023
    Assignee: OSAKA UNIVERSITY
    Inventors: Akira Kikuchi, Katsumi Fumoto, Hirokazu Kimura
  • Publication number: 20220249538
    Abstract: The purpose of the present invention is to provide a novel tumor treatment agent. In GREB1-positive tumors that do not exhibit sex hormone sensitivity, GREB1 is a downstream target gene of the Wnt/?-catenin signal. Through the use as an active ingredient of a substance that can inhibit GREB1 expression, the growth of GREB1-positive tumor cells that do not exhibit sex hormone sensitivity can be effectively inhibited and such a tumor can be treated.
    Type: Application
    Filed: May 22, 2020
    Publication date: August 11, 2022
    Inventors: Akira Kikuchi, Shinji Matsumoto, Taku Yamamichi
  • Publication number: 20220231615
    Abstract: A secondary magnetic excitation generator-motor device that inputs a first ignition pulse command to a three-level NPC power converter such that a detected excitation current value corresponds with an excitation current command value, the secondary magnetic excitation generator-motor device having a function of identifying a first phase, a second phase, or a third phase in descending order of a current absolute value, wherein a pulse switch to output an ignition pulse command to the three-level NPC power converter switches the ignition pulse command to the second ignition pulse command when a current absolute value exceeds a set overcurrent level 1, and switches the ignition pulse command to the first ignition pulse command when current absolute values for three phases are all equal to or smaller than a set overcurrent level 2.
    Type: Application
    Filed: August 8, 2019
    Publication date: July 21, 2022
    Inventors: Akira BANDO, Hironari KAWAZOE, Akira KIKUCHI
  • Patent number: 11293007
    Abstract: A method for producing a Wnt protein-afamin complex, the method comprising the steps of culturing Wnt protein-expressing cells in a culture medium containing a purified afamin or a recombinant afamin or co-culturing Wnt protein-expressing cells and recombinant afamin-expressing cells or culturing cells expressing both a Wnt protein and afamin; obtaining the culture supernatant; and optionally performing affinity purification to obtain the Wnt protein-afamin complex from the culture supernatant.
    Type: Grant
    Filed: September 10, 2019
    Date of Patent: April 5, 2022
    Assignee: OSAKA UNIVERSITY
    Inventors: Junichi Takagi, Emiko Mihara, Akira Kikuchi
  • Publication number: 20210317459
    Abstract: The purpose of the present invention is to provide an antisense oligonucleotide that targets an ARL4C molecule and exerts an antitumor effect in vivo, and a nucleic acid drug using the antisense oligonucleotide. An antisense oligonucleotide that has a base sequence consisting of at least 10 consecutive bases contained in the base sequence represented by SEQ ID NO: 1. This antisense oligonucleotide targets an ARL4C molecule and thus can inhibit the expression of ARL4C in a tumor cell in vitro and suppress the migration and proliferation thereof. When systemically administered, moreover, the antisense oligonucleotide can exert an excellent antitumor effect in vivo too.
    Type: Application
    Filed: September 4, 2019
    Publication date: October 14, 2021
    Inventors: Akira KIKUCHI, Shinji MATSUMOTO, Satoshi OBIKA, Yuya KASAHARA, Takumi FUKUMOTO
  • Patent number: 11088569
    Abstract: The purpose of the present invention is to provide a power flow monitoring device for a power system, a power system stabilization device, and a power flow monitoring method for a power system, which are highly reliable and accurate.
    Type: Grant
    Filed: September 13, 2017
    Date of Patent: August 10, 2021
    Assignee: Hitachi, Ltd.
    Inventors: Yuki Tsujii, Kenedward Kawakita, Masatoshi Kumagai, Masahiro Watanabe, Akira Kikuchi
  • Patent number: 10873273
    Abstract: An apparatus includes: an inverter converting generated power of renewable energy resources to predetermined alternating-current power for output to a power transmission network; a PWM control unit controlling the inverter; a first detecting unit detecting the input voltage and current to the inverter; a second detecting unit detecting the output voltage, current, and frequency of the inverter; a power change deciding unit calculating the input and output powers of the inverter and the difference therebetween from the voltage and current of each of the input and output detected by the detecting units, and calculating a correction output power command with reference to an output power command; and a virtual synchronous inertia control unit calculating a virtual inertia characteristic based on the voltage, current, and frequency of the output detected by the second detecting unit and the correction output power command, and outputting a reference command to a PWM control unit.
    Type: Grant
    Filed: March 21, 2018
    Date of Patent: December 22, 2020
    Assignee: Hitachi, Ltd.
    Inventors: Chia Tse Lee, Akira Kikuchi
  • Publication number: 20200377580
    Abstract: The purpose of the present invention is to provide an anti-CKAP4 monoclonal antibody that inhibits the binding of DKK1 and CKAP4 and exhibits an exceptional antitumor effect. Provided is an anti-CKAP4 monoclonal antibody that recognizes at least part of the 451-455 region, at least part of the 481-485 region, at least part of the 502-510 region, at least part of the 503-524 region and at least part of the 585-590 region, or at least part of the 585-592 region of the amino acid sequence (amino acid sequence of CKAP4) represented by SEQ ID NO:1 as an epitope, the anti-CKAP4 monoclonal antibody effectively inhibiting the binding of DKK1 and CKAP4, the activation of AKT of S2-CP8 cells, and the proliferative ability of S2-CP8 cells or the migratory ability of S2-CP8 cells, and exhibiting an exceptional antitumor effect.
    Type: Application
    Filed: September 26, 2018
    Publication date: December 3, 2020
    Inventors: Akira KIKUCHI, Katsumi FUMOTO, Hirokazu KIMURA
  • Patent number: 10756571
    Abstract: Providing a power system and a method for stabilizing a system, in which the number of generators to be disconnected is reduced to narrow an area influenced by a grid fault in the case where the reliability of the state estimation calculation is judged to be high.
    Type: Grant
    Filed: July 11, 2016
    Date of Patent: August 25, 2020
    Assignee: Hitachi, Ltd.
    Inventors: Tomomichi Ito, Akira Kikuchi, Masahiro Watanabe
  • Patent number: 10618954
    Abstract: Disclosed is to identify a target molecule that is involved in Dkk1-induced hyperproliferation of tumor cells to provide a novel antitumor agent. Cytoskeleton-associated protein 4 (CKAP4) specifically regulates the hyperproliferation effects that are induced by dickkopf-related protein 1 (Dkk1), and proliferation of tumor cells can be suppressed by inhibiting expression or function of CKAP4 in the tumor cells.
    Type: Grant
    Filed: January 28, 2016
    Date of Patent: April 14, 2020
    Assignee: OSAKA UNIVERSITY
    Inventors: Akira Kikuchi, Katsumi Fumoto, Hirokazu Kimura
  • Publication number: 20200099315
    Abstract: An apparatus includes: an inverter converting generated power of renewable energy resources to predetermined alternating-current power for output to a power transmission network; a PWM control unit controlling the inverter; a first detecting unit detecting the input voltage and current to the inverter; a second detecting unit detecting the output voltage, current, and frequency of the inverter; a power change deciding unit calculating the input and output powers of the inverter and the difference therebetween from the voltage and current of each of the input and output detected by the detecting units, and calculating a correction output power command with reference to an output power command; and a virtual synchronous inertia control unit calculating a virtual inertia characteristic based on the voltage, current, and frequency of the output detected by the second detecting unit and the correction output power command, and outputting a reference command to a PWM control unit.
    Type: Application
    Filed: March 21, 2018
    Publication date: March 26, 2020
    Inventors: Chia Tse LEE, Akira KIKUCHI
  • Patent number: 10550364
    Abstract: Provided is a novel method for producing a Wnt protein, which method comprises (1) a step of performing affinity purification targeting afamin to obtain a Wnt protein from a culture product, and/or (2) a step of performing affinity purification to obtain a Wnt protein in the form of a complex with afamin from a culture product. The method enables a Wnt protein having high Wnt activity to be produced in a simple and brief manner without use of special equipment.
    Type: Grant
    Filed: December 24, 2015
    Date of Patent: February 4, 2020
    Assignee: OSAKA UNIVERSITY
    Inventors: Junichi Takagi, Emiko Mihara, Akira Kikuchi
  • Publication number: 20190390160
    Abstract: Provided is a novel method for producing a Wnt protein, which method comprises (1) a step of performing affinity purification targeting afamin to obtain a Wnt protein from a culture product, and/or (2) a step of performing affinity purification to obtain a Wnt protein in the form of a complex with afamin from a culture product. The method enables a Wnt protein having high Wnt activity to be produced in a simple and brief manner without use of special equipment.
    Type: Application
    Filed: September 10, 2019
    Publication date: December 26, 2019
    Applicant: OSAKA UNIVERSITY
    Inventors: Junichi TAKAGI, Emiko MIHARA, Akira KIKUCHI
  • Publication number: 20190305590
    Abstract: Providing a power system and a method for stabilizing a system, in which the number of generators to be disconnected is reduced to narrow an area influenced by a grid fault in the case where the reliability of the state estimation calculation is judged to be high.
    Type: Application
    Filed: July 11, 2016
    Publication date: October 3, 2019
    Inventors: Tomomichi ITO, Akira KIKUCHI, Masahiro WATANABE
  • Publication number: 20190237997
    Abstract: The purpose of the present invention is to provide a power flow monitoring device for a power system, a power system stabilization device, and a power flow monitoring method for a power system, which are highly reliable and accurate.
    Type: Application
    Filed: September 13, 2017
    Publication date: August 1, 2019
    Inventors: Yuki TSUJII, Kenedward KAWAKITA, Masatoshi KUMAGAI, Masahiro WATANABE, Akira KIKUCHI
  • Patent number: 10182889
    Abstract: A magnet assembly for a dental magnetic attachment comprising a cup-shaped yoke of substantially Ni-free ferritic stainless steel, a permanent magnet received in a recess of the cup-shaped yoke, a seal member sealing an opening of the cup-shaped yoke, and an abutment-welded portion of the seal member and the cup-shaped yoke; the seal member comprising a center portion of substantially Ni-free ferritic stainless steel; an intermediate portion of substantially Ni-free austenitic stainless steel having a nitrogen content of 0.5-2.0% by mass, and a peripheral portion made of substantially Ni-free ferritic stainless steel having a nitrogen content of 1.3% or less by mass, smaller than in the intermediate portion.
    Type: Grant
    Filed: March 19, 2015
    Date of Patent: January 22, 2019
    Assignee: HITACHI METALS, LTD.
    Inventors: Yukyo Takada, Masatoshi Takahashi, Akira Kikuchi