Patents by Inventor Akira Mitsui
Akira Mitsui has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20220022851Abstract: The present invention provides a method for determining the likelihood of colorectal cancer development in a human ulcerative colitis patient, the method including: a measurement step of measuring methylation rates of one or more CpG sites present in specific differentially methylated regions in DNA recovered from a biological sample collected from the human ulcerative colitis patient; and a determination step of determining the likelihood of colorectal cancer development in the human ulcerative colitis patient based on average methylation rates of the differentially methylated regions which are calculated based on the methylation rates measured in the measurement step and a preset reference value or a preset multivariate discrimination expression, in which the reference value is a value for identifying a cancerous ulcerative colitis patient and a non-cancerous ulcerative colitis patient, which is set for the methylation rate of each differentially methylated region, and the multivariate discrimination expresType: ApplicationFiled: October 13, 2021Publication date: January 27, 2022Applicants: Hanumat Co., Ltd., EA Pharma Co., Ltd.Inventors: Masato KUSUNOKI, Yuji TOIYAMA, Koji TANAKA, Toshimitsu ARAKI, Akira MITSUI, Kenji TAKEHANA, Tsutomu UMEZAWA
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Patent number: 11094909Abstract: A thin film of amorphous metal oxide includes zinc (Zn), silicon (Si) and oxygen (O), the atomic ratio of Zn/(Zn+Si) being 0.30 to 0.95.Type: GrantFiled: June 10, 2016Date of Patent: August 17, 2021Assignee: JAPAN SCIENCE AND TECHNOLOGY AGENCYInventors: Hideo Hosono, Yoshitake Toda, Toshinari Watanabe, Naomichi Miyakawa, Kazuhiro Ito, Satoru Watanabe, Akira Mitsui, Kazuto Ohkoshi
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Patent number: 10723840Abstract: Provided is a polyphenylene ether resin composition having excellent heat aging resistance and fluidity. A polyphenylene ether includes at least one structural unit selected from chemical formulae (1), (2), and (3).Type: GrantFiled: October 3, 2016Date of Patent: July 28, 2020Assignee: ASAHI KASEI KABUSHIKI KAISHAInventors: Chihiro Orimo, Toru Yamaguchi, Mihoko Yamamoto, Akira Mitsui
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Patent number: 10696843Abstract: Provided is a polyphenylene ether flame-retardant resin composition having excellent flame retardance and long-term flame retardance. The flame-retardant resin composition contains: (A) a resin including (A-1) a polyphenylene ether; and (B) a flame retardant. The (A-1) component has a content of 50 mass % or more when the flame-retardant resin composition minus ash content, corresponding to a residue obtained upon burning of the flame-retardant resin composition, is taken to be 100 mass %. A shaped article of 12.6 cm in length, 1.3 cm in width, and 1.6 mm in thickness formed from the flame-retardant resin composition exhibits a rate of change of chloroform-insoluble content of 15 mass % or less through aging in which the shaped article is left for 1,000 hours at 150° C. in an atmospheric air.Type: GrantFiled: October 3, 2016Date of Patent: June 30, 2020Assignee: ASAHI KASEI KABUSHIKI KAISHAInventors: Chihiro Maeda, Mihoko Yamamoto, Akira Mitsui
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Publication number: 20190352721Abstract: The present invention provides a method for determining the likelihood of sporadic colorectal cancer development, the method including: a measurement step of measuring methylation rates of one or more CpG sites present in specific differentially methylated regions, in DNA recovered from a biological sample collected from a human subject; and a determination step of determining the likelihood of sporadic colorectal cancer development in the human subject, based on average methylation rates of the differentially methylated regions which are calculated based on the methylation rates measured and a preset reference value or a preset multivariate discrimination expression, in which the reference value is a value for identifying a sporadic colorectal cancer patient and a non-sporadic colorectal cancer patient, which is set for the average methylation rate of each differentially methylated region, and the multivariate discrimination expression includes, as variables, average methylation rates of one or more differenType: ApplicationFiled: September 28, 2017Publication date: November 21, 2019Applicants: Hanumat Co., Ltd., EA Pharma Co., Ltd.Inventors: Masato KUSUNOKI, Yuji TOIYAMA, Akira MITSUI, Kenji TAKEHANA, Tsutomu UMEZAWA
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Patent number: 10435508Abstract: Provided is a flame retardant resin composition excellent in flame retardance, and surface smoothness, appearance, flame retardance and electrical properties after a long-term thermal aging (e.g. 150° C., 500 hours) while maintaining mechanical and electrical properties. The disclosed flame retardant resin composition is a flame retardant resin composition containing a polyphenylene ether, in which, based on UL94 flammability test, an average burning time of a molded product having a length of 12.6 cm, a width of 1.3 cm and a thickness of 1.6 mm formed of the flame retardant resin composition before and after the aging processing in which the molded product is left to stand at 150° C. for 1000 hours under the atmospheric pressure is within 10 seconds, and a change rate of chloroform-insoluble component of the molded product before and after the aging processing is 15 mass % or less.Type: GrantFiled: October 3, 2017Date of Patent: October 8, 2019Assignee: ASAHI KASEI KABUSHIKI KAISHAInventors: Chihiro Maeda, Mihoko Yamamoto, Akira Mitsui
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Publication number: 20190241970Abstract: The present invention provides a method for determining the likelihood of colorectal cancer development in a human ulcerative colitis patient, the method including: a measurement step of measuring methylation rates of one or more CpG sites present in specific differentially methylated regions in DNA recovered from a biological sample collected from the human ulcerative colitis patient; and a determination step of determining the likelihood of colorectal cancer development in the human ulcerative colitis patient based on average methylation rates of the differentially methylated regions which are calculated based on the methylation rates measured in the measurement step and a preset reference value or a preset multivariate discrimination expression, in which the reference value is a value for identifying a cancerous ulcerative colitis patient and a non-cancerous ulcerative colitis patient, which is set for the methylation rate of each differentially methylated region, and the multivariate discrimination expresType: ApplicationFiled: July 7, 2017Publication date: August 8, 2019Applicants: Hanumat Co., Ltd., EA Pharma Co., Ltd.Inventors: Masato KUSUNOKI, Yuji TOIYAMA, Koji TANAKA, Toshimitsu ARAKI, Akira MITSUI, Kenji TAKEHANA, Tsutomu UMEZAWA
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Publication number: 20190119492Abstract: Provided is a polyphenylene ether flame-retardant resin composition having excellent flame retardance and long-term flame retardance. The flame-retardant resin composition contains: (A) a resin including (A-1) a polyphenylene ether; and (B) a flame retardant. The (A-1) component has a content of 50 mass % or more when the flame-retardant resin composition minus ash content, corresponding to a residue obtained upon burning of the flame-retardant resin composition, is taken to be 100 mass %. A shaped article of 12.6 cm in length, 1.3 cm in width, and 1.6 mm in thickness formed from the flame-retardant resin composition exhibits a rate of change of chloroform-insoluble content of 15 mass % or less through aging in which the shaped article is left for 1,000 hours at 150° C. in an atmospheric air.Type: ApplicationFiled: October 3, 2016Publication date: April 25, 2019Applicant: ASAHI KASEI KABUSHIKI KAISHAInventors: Chihiro MAEDA, Mihoko YAMAMOTO, Akira MITSUI
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Publication number: 20190002637Abstract: Provided is a polyphenylene ether resin composition having excellent heat aging resistance and fluidity. A polyphenylene ether includes at least one structural unit selected from chemical formulae (1), (2), and (3).Type: ApplicationFiled: October 3, 2016Publication date: January 3, 2019Applicant: ASAHI KASEI KABUSHIKI KAISHAInventors: Chihiro ORIMO, Toru YAMAGUCHI, Mihoko YAMAMOTO, Akira MITSUI
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Patent number: 10059802Abstract: Provided is a method for producing polyphenylene ether (PPE) having excellent mechanical properties, heat aging resistance, and color, and in which the content of impurities such as low molecular weight components and catalyst metal is low. The method for producing PPE includes: performing oxidative polymerization of a phenolic compound in a polymerization solution containing the phenolic compound, a catalyst, and an aromatic solvent to obtain a PPE mixed liquid; precipitating PPE to obtain a slurry containing particulate PPE through addition of a polar solvent to the PPE mixed liquid; solid-liquid separating the slurry to obtain wet PPE particles; washing the wet PPE particles to obtain PPE particles through at least one cycle of a washing and solid-liquid separation process in which washing is performed with a washing liquid containing an aromatic solvent and a polar solvent, and in which solid-liquid separation is performed; and drying the PPE particles.Type: GrantFiled: March 22, 2017Date of Patent: August 28, 2018Assignee: ASAHI KASEI KABUSHIKI KAISHAInventors: Shigeru Yamamoto, Akira Mitsui
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Publication number: 20180094102Abstract: Provided is a flame retardant resin composition excellent in flame retardance, and surface smoothness, appearance, flame retardance and electrical properties after a long-term thermal aging (e.g. 150° C., 500 hours) while maintaining mechanical and electrical properties. The disclosed flame retardant resin composition is a flame retardant resin composition containing a polyphenylene ether, in which, based on UL94 flammability test, an average burning time of a molded product having a length of 12.6 cm, a width of 1.3 cm and a thickness of 1.6 mm formed of the flame retardant resin composition before and after the aging processing in which the molded product is left to stand at 150° C. for 1000 hours under the atmospheric pressure is within 10 seconds, and a change rate of chloroform-insoluble component of the molded product before and after the aging processing is 15 mass % or less.Type: ApplicationFiled: October 3, 2017Publication date: April 5, 2018Applicant: ASAHI KASEI KABUSHIKI KAISHAInventors: Chihiro MAEDA, Mihoko YAMAMOTO, Akira MITSUI
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Publication number: 20180057685Abstract: Provided is a resin composition having excellent flame retardance, molding processability, and post-heat aging flame retardance. A flame-retardant resin composition contains: (A) a polyphenylene ether; (B) at least one thermoplastic resin selected from the group consisting of (B-1) a polystyrene resin, (B-2) a polyamide resin, (B-3) a polypropylene resin, and (B-4) a polyphenylene sulfide resin; and (C) a flame retardant. The (A) component has a content of less than 50 mass % when the flame-retardant resin composition minus ash content is taken to be 100 mass %. The flame-retardant resin composition has a flame retardance level of V-0 as measured by a UL 94 vertical burning test. A molded article formed from the flame-retardant resin composition exhibits a rate of change of chloroform-insoluble content of no greater than 15 mass % before and after being subjected to aging in which the molded article is left for 1,000 hours at 150° C. in an atmospheric environment.Type: ApplicationFiled: June 20, 2017Publication date: March 1, 2018Applicant: ASAHI KASEI KABUSHIKI KAISHAInventors: Chihiro MAEDA, Mihoko YAMAMOTO, Akira MITSUI
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Patent number: 9777114Abstract: A method for producing a polyphenylene ether (PPE) provides the PPE that includes less gel and that is good in mechanical property and heat resistance, wherein the method includes a polymerization step of subjecting a phenol compound to oxidative polymerization in the presence of a polymerization catalyst in a good solvent for a polyphenylene ether to thereby provide a polyphenylene ether solution, a catalyst extraction step of adding an aqueous chelating agent solution to the polyphenylene ether solution and extracting the polymerization catalyst into the aqueous chelating agent solution to thereby provide a catalyst-removed polyphenylene ether solution, a concentration step of removing a part of the good solvent from the catalyst-removed polyphenylene ether solution to provide a concentrated polyphenylene ether solution, and a gel removal step of removing at least a visually observable chloroform-insoluble substance from the concentrated polyphenylene ether solution, to thereby provide a gel-removed polypheType: GrantFiled: May 31, 2016Date of Patent: October 3, 2017Assignee: ASAHI KASEI KABUSHIKI KAISHAInventors: Shigeru Yamamoto, Akira Mitsui
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Publication number: 20170275424Abstract: Provided is a method for producing polyphenylene ether (PPE) having excellent mechanical properties, heat aging resistance, and color, and in which the content of impurities such as low molecular weight components and catalyst metal is low. The method for producing PPE includes: performing oxidative polymerization of a phenolic compound in a polymerization solution containing the phenolic compound, a catalyst, and an aromatic solvent to obtain a PPE mixed liquid; precipitating PPE to obtain a slurry containing particulate PPE through addition of a polar solvent to the PPE mixed liquid; solid-liquid separating the slurry to obtain wet PPE particles; washing the wet PPE particles to obtain PPE particles through at least one cycle of a washing and solid-liquid separation process in which washing is performed with a washing liquid containing an aromatic solvent and a polar solvent, and in which solid-liquid separation is performed; and drying the PPE particles.Type: ApplicationFiled: March 22, 2017Publication date: September 28, 2017Applicant: ASAHI KASEI KABUSHIKI KAISHAInventors: Shigeru YAMAMOTO, Akira MITSUI
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Publication number: 20170240742Abstract: It is intended to provide a polyphenylene ether resin composition that has favorable fluidity in molding while ensuring sufficiently high heat resistance and/or favorable mechanical properties. The present invention provides a polyphenylene ether resin composition comprising: 50% by mass or more and 99% by mass or less of a polyphenylene ether resin (A) having a reduced viscosity of 0.33 dl/g or more and 0.46 dl/g or less measured in an amount of 0.5 g/dl at 30° C. using a chloroform solvent; 0% by mass or more and 49% by mass or less of a polystyrene resin (B); and 1% by mass or more and 15% by mass or less of a styrene-acrylonitrile resin (C) having an acrylonitrile content of 16% by mass or more and 45% by mass or less.Type: ApplicationFiled: February 18, 2016Publication date: August 24, 2017Applicant: Asahi Kasei Chemicals CorporationInventors: Toru YAMAGUCHI, Akira MITSUI
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Patent number: 9735446Abstract: To provide a dense beta-alumina-based sintered compact having a high ionic conductivity as a solid electrolyte by firing at a low temperature to suppress the volatilization of Na2O and its production method. By adding RNbO3 which is a material having a low melting point to a beta-alumina powder, followed by firing, it is possible to obtain a beta-alumina-based sintered compact having a low firing temperature and containing, as the main component, dense ?? alumina crystals which are free from anomalous grain growth during the firing process.Type: GrantFiled: August 29, 2014Date of Patent: August 15, 2017Assignee: Asahi Glass Company, LimitedInventor: Akira Mitsui
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Patent number: 9458580Abstract: A compaction roller comprises a vibration device for generating vibrations when driven by a vibration motor; a pair of right and left traveling drive shafts, while traveling driving outside tires and their adjoining inside tires synchronously, for transmitting the vibrations of the vibration device to the outside tires and inside tires; a pair of right and left traveling motors respectively for driving their associated traveling drive shafts; and, a pair of right and left first support brackets mounted through a first vibration proof device 6 on a vehicle body and interposed between the outside tires and inside tires for supporting the traveling drive shafts through bearings, wherein the vibration device includes a vibration source disposed within the traveling drive shafts. According to the compaction roller, a side overhang can be eliminated or reduced, and enabling prevention of the lowered vibration compacting function of the tires.Type: GrantFiled: August 28, 2015Date of Patent: October 4, 2016Assignee: Sakai Heavy Industries, Ltd.Inventors: Sadayoshi Suzuki, Hiroaki Neko, Akira Mitsui
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Publication number: 20160285027Abstract: A thin film of amorphous metal oxide includes zinc (Zn), silicon (Si) and oxygen (O), the atomic ratio of Zn/(Zn+Si) being 0.30 to 0.95.Type: ApplicationFiled: June 10, 2016Publication date: September 29, 2016Applicants: JAPAN SCIENCE AND TECHNOLOGY AGENCY, TOKYO INSTITUTE OF TECHNOLOGY, ASAHI GLASS COMPANY, LIMITEDInventors: HIDEO HOSONO, YOSHITAKE TODA, TOSHINARI WATANABE, NAOMICHI MIYAKAWA, KAZUHIRO ITO, SATORU WATANABE, AKIRA MITSUI, KAZUTO OHKOSHI
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Publication number: 20160111263Abstract: There is provided a sputtering target for forming an amorphous film, the sputtering target including an electrically conductive mayenite compound, wherein electron density of the electrically conductive mayenite compound is greater than or equal to 3×1020 cm?3, and wherein the electrically conductive mayenite compound includes one or more elements that are selected from a group including C, Fe, Na, and Zr.Type: ApplicationFiled: December 22, 2015Publication date: April 21, 2016Applicant: Asahi Glass Company, LimitedInventors: Kazuhiro ITO, Satoru WATANABE, Naomichi MIYAKAWA, Toshinari WATANABE, Akira MITSUI
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Publication number: 20160060821Abstract: A compaction roller comprises a vibration device for generating vibrations when driven by a vibration motor; a pair of right and left traveling drive shafts, while traveling driving outside tires and their adjoining inside tires synchronously, for transmitting the vibrations of the vibration device to the outside tires and inside tires; a pair of right and left traveling motors respectively for driving their associated traveling drive shafts; and, a pair of right and left first support brackets mounted through a first vibration proof device 6 on a vehicle body and interposed between the outside tires and inside tires for supporting the traveling drive shafts through bearings, wherein the vibration device includes a vibration source disposed within the traveling drive shafts. According to the compaction roller, a side overhang can be eliminated or reduced, and enabling prevention of the lowered vibration compacting function of the tires.Type: ApplicationFiled: August 28, 2015Publication date: March 3, 2016Applicant: Sakai Heavy Industries, Ltd.Inventors: Sadayoshi Suzuki, Hiroaki Neko, Akira Mitsui