Patents by Inventor Akira Myomoto

Akira Myomoto has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9873916
    Abstract: This invention relates to a composition and a method for prediction of a response to Trastuzumab therapy in a breast cancer patient, and more specifically, a composition, a kit, a DNA chip, and a method for predicting a response to Trastuzumab therapy by using polynucleotides each comprising a nucleotide sequence represented by any of SEQ ID NOs: 1 to 9, 11 to 19, and 21 to 23 in the Sequence Listing or a nucleotide sequence derived therefrom by substitution of u with t, mutants thereof, derivatives thereof, or fragments thereof comprising at least 16 continuous nucleotides, or a polynucleotide comprising a complementary sequence thereof, and using an increase or decrease in Her2 protein expression level as an indicator.
    Type: Grant
    Filed: April 25, 2012
    Date of Patent: January 23, 2018
    Assignees: TORAY INDUSTRIES, INC., KYOTO UNIVERSITY
    Inventors: Akira Myomoto, Satoko Kozono, Fumiaki Sato, Masakazu Toi, Takayuki Ueno, Zhipeng Wang, Gozoh Tsujimoto, Kazuharu Shimizu
  • Patent number: 8945849
    Abstract: This invention relates to a composition, kit, or DNA chip for use in diagnosis of esophageal cancer, which comprises a plurality of polynucleotides selected from the group consisting of polynucleotides whose expression levels are varied in esophageal cancer tissues obtained from esophageal cancer patients when compared with cancer-free esophageal tissues obtained from esophageal cancer patients, mutants thereof, and fragments thereof, and to a method for detecting esophageal cancer using the composition, kit, or DNA chip.
    Type: Grant
    Filed: May 21, 2009
    Date of Patent: February 3, 2015
    Assignees: Toray Industries, Inc., Kyoto University
    Inventors: Akira Myomoto, Satoko Kozono, Hideo Akiyama, Hitoshi Nobumasa, Yutaka Shimada, Gozoh Tsujimoto
  • Publication number: 20140073533
    Abstract: This invention relates to a composition and a method for prediction of a response to Trastuzumab therapy in a breast cancer patient, and more specifically, a composition, a kit, a DNA chip, and a method for predicting a response to Trastuzumab therapy by using polynucleotides each comprising a nucleotide sequence represented by any of SEQ ID NOs: 1 to 9, 11 to 19, and 21 to 23 in the Sequence Listing or a nucleotide sequence derived therefrom by substitution of u with t, mutants thereof, derivatives thereof, or fragments thereof comprising at least 16 continuous nucleotides, or a polynucleotide comprising a complementary sequence thereof, and using an increase or decrease in Her2 protein expression level as an indicator.
    Type: Application
    Filed: April 25, 2012
    Publication date: March 13, 2014
    Applicants: KYOTO UNIVERSITY, TORAY INDUSTRIES, INC
    Inventors: Akira Myomoto, Satoko Kozono, Fumiaki Sato, Masakazu Toi, Takayuki Ueno, Zhipeng Wang, Gozoh Tsujimoto, Kazuharu Shimizu
  • Patent number: 8198025
    Abstract: This invention relates to a composition, kit, or DNA chip comprising polynucleotides and antibodies as probes for detecting, determining, or predicting the presence or metastasis of esophageal cancer, and to a method for detecting, determining, or predicting the presence or metastasis of esophageal cancer using the same.
    Type: Grant
    Filed: April 6, 2011
    Date of Patent: June 12, 2012
    Assignees: Toray Industries, Inc., Kyoto University
    Inventors: Hideo Akiyama, Satoko Kozono, Akira Myomoto, Osamu Nomura, Hitoshi Nobumasa, Yoshinori Tanaka, Shiori Tomoda, Yutaka Shimada, Gozoh Tsujimoto
  • Publication number: 20110201520
    Abstract: This invention relates to a composition, kit, or DNA chip comprising polynucleotides and antibodies as probes for detecting, determining, or predicting the presence or metastasis of esophageal cancer, and to a method for detecting, determining, or predicting the presence or metastasis of esophageal cancer using the same.
    Type: Application
    Filed: April 6, 2011
    Publication date: August 18, 2011
    Applicants: TORAY INDUSTRIES, INC., Kyoto University
    Inventors: Hideo Akiyama, Satoko Kozono, Akira Myomoto, Osamu Nomura, Hitoshi Nobumasa, Yoshinori Tanaka, Shiori Tomoda, Yutaka Shimada, Gozoh Tsujimoto
  • Publication number: 20110098185
    Abstract: This invention relates to a composition, kit, or DNA chip for use in diagnosis of esophageal cancer, which comprises a plurality of polynucleotides selected from the group consisting of polynucleotides whose expression levels are varied in esophageal cancer tissues obtained from esophageal cancer patients when compared with cancer-free esophageal tissues obtained from esophageal cancer patients, mutants thereof, and fragments thereof, and to a method for detecting esophageal cancer using the composition, kit, or DNA chip.
    Type: Application
    Filed: May 21, 2009
    Publication date: April 28, 2011
    Inventors: Akira Myomoto, Satoko Kozono, Hideo Akiyama, Hitoshi Nobumasa, Yutaka Shimada, Gozoh Tsujimoto
  • Patent number: 7932032
    Abstract: This invention relates to a composition, kit, or DNA chip comprising polynucleotides and antibodies as probes for detecting, determining, or predicting the presence or metastasis of esophageal cancer, and to a method for detecting, determining, or predicting the presence or metastasis of esophageal cancer using the same.
    Type: Grant
    Filed: May 2, 2006
    Date of Patent: April 26, 2011
    Assignees: Toray Industries, Inc., Kyoto University
    Inventors: Hideo Akiyama, Satoko Kozono, Akira Myomoto, Osamu Nomura, Hitoshi Nobumasa, Yoshinori Tanaka, Shiori Tomoda, Yutaka Shimada, Gozoh Tsujimoto
  • Publication number: 20100152055
    Abstract: This invention relates to a composition, kit, DNA chip, and use thereof for detecting, diagnosing, and predicting metastasis of kidney cancer and/or for predicting the prognosis for kidney cancer, comprising one or a plurality of polynucleotides selected from the group consisting of polynucleotides, mutants thereof or fragments thereof, the expression levels of which vary in kidney cancer cells from a patient with a poor prognosis when compared with that in kidney cancer cells from a patient with a good prognosis; or antibodies or fragments thereof that bind specifically to polypeptides, mutants thereof or fragments thereof, the expression levels of which vary in the similar manner.
    Type: Application
    Filed: September 1, 2006
    Publication date: June 17, 2010
    Inventors: Satoko Kozono, Hideo Akiyama, Akira Myomoto, Yoshinori Tanaka, Giman Jung, Hitoshi Nobumasa, Osamu Nomura, Osamu Ogawa, Eijiro Nakamura, Gozo Tsujimoto
  • Publication number: 20090270267
    Abstract: This invention relates to a composition, kit, or DNA chip comprising polynucleotides and antibodies as probes for detecting, determining, or predicting the presence or metastasis of esophageal cancer, and to a method for detecting, determining, or predicting the presence or metastasis of esophageal cancer using the same.
    Type: Application
    Filed: May 2, 2006
    Publication date: October 29, 2009
    Applicants: TORAY INDUSTRIES, INC., Kyoto University
    Inventors: Hideo Akiyama, Satoko Kozono, Akira Myomoto, Osamu Nomura, Hitoshi Nobumasa, Yoshinori Tanaka, Shiori Tomoda, Yutaka Shimada, Gozoh Tsujimoto