Patents by Inventor Akira Ookubo

Akira Ookubo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9636870
    Abstract: A powder transfer mechanism laminates powder layers containing water-soluble powder as a main component one by one at a modeling portion. An inkjet line head injects a water-based ink that dissolves the powder in an area of an uppermost layer of the powder layers laminated by the powder transfer mechanism, the area corresponding to a cross-sectional shape of a modeled object. Then, a heater heats the powder for each layer of the powder layers. Further, the heater heats the powder after the water-based ink is injected by the inkjet line head or before the water-based ink is injected by the inkjet line head. The present invention can be applied to a modeling apparatus, for example.
    Type: Grant
    Filed: May 14, 2009
    Date of Patent: May 2, 2017
    Assignee: Sony Corporation
    Inventors: Junichi Kuzusako, Masanobu Yamamoto, Akira Ookubo, Toshihiro Kamewa, Tomohide Koizumi, Kazuma Tamura, Takeshi Matsui
  • Patent number: 9149434
    Abstract: The present invention provides a core particle for a pharmaceutical preparation which features the requisite properties of a core particle, and which has enough chemical stability, and in which reactivity with the drug (an active pharmaceutical ingredient) is limited or prevented. More specifically, the present invention relates to a core particle wherein a film containing an active pharmaceutical ingredient can be formed on the surface thereof, and (1) the core particle comprises a pharmaceutically acceptable inorganic material, (2) the inorganic material is poorly soluble in water, and (3) pH of a solution of the inorganic material is 5 to 8.
    Type: Grant
    Filed: September 8, 2008
    Date of Patent: October 6, 2015
    Assignee: TOMITA PHARMACEUTICAL CO., LTD.
    Inventors: Masashi Konishi, Shouichi Oonishi, Akira Ookubo, Masashi Yunoki, Ariumi Kawamoto, Kanako Hattori
  • Patent number: 8668852
    Abstract: The present invention provides a powder for molding that reduces or prevents drawbacks such as unevenness and low fluidity when a mixed powder is used as a powder for molding. The present invention relates to powders for molding including particles in which each particle contains an inorganic component and a water-soluble organic polymer component and methods for producing the same.
    Type: Grant
    Filed: February 26, 2010
    Date of Patent: March 11, 2014
    Assignee: Tomita Pharmaceutical Co., Ltd.
    Inventors: Akira Ookubo, Tomohide Koizumi, Kazuma Tamura
  • Publication number: 20140030346
    Abstract: Provided is a core particle for a pharmaceutical preparation, capable of delivering a relatively large amount of a drug active ingredient, in particular, at a predetermined timing. This invention relates to a disintegrable core particle for a pharmaceutical preparation, which core particle is adapted for formation, on the particle surface, of a drug active ingredient-containing film, wherein (1) the core particle includes a pharmaceutically acceptable inorganic material and a disintegration promoting agent, (2) the inorganic material is poorly soluble in water, (3) the inorganic material has a content of from 50 to 95 wt %, and (4) the core particle has a bulk density of at least 0.6 g/mL.
    Type: Application
    Filed: December 27, 2011
    Publication date: January 30, 2014
    Inventors: Masashi Konishi, Ariumi Kawamoto, Akira Ookubo, Masashi Yunoki
  • Publication number: 20130059151
    Abstract: Provided is a magnesium oxide for pharmaceutical use that, when mixed with a drug that is unstable in acid, demonstrates high stabilizing effects on the drug while also demonstrating superior stability of the magnesium oxide per se. The magnesium oxide for pharmaceutical use is used by being mixed with a drug that is unstable in acid, and has a specific surface area as determined according to the BET method of 20 m2/g to 200 m2/g and a degree of activation of 40 Img/g to 200 Img/g.
    Type: Application
    Filed: October 20, 2011
    Publication date: March 7, 2013
    Applicant: TOMITA PHARMACEUTICAL CO., LTD.
    Inventors: Masashi Konishi, Shouichi Oonishi, Akira Ookubo, Masashi Yunoki, Ariumi Kawamoto
  • Patent number: 8186415
    Abstract: A method for manufacturing a mold, including steps of (a) expanding a powder mixture containing a water-soluble inorganic salt powder and a water-soluble organic polymer powder in a plane on a table and then selectively spraying a spray liquid containing at least one selected from a water-miscible organic solvent and water through a nozzle on this powder mixture layer to make a bonding strength among particles of the powder mixture in a sprayed region higher than that among particles of the powder mixture in an unsprayed region, (b) further expanding the powder mixture on the powder mixture layer after spraying and then selectively spraying the spray liquid through the nozzle on this powder mixture layer, (c) repeatedly conducting the step (b) over several times to form a mold shaped by the sprayed regions, and (d) taking out the mold.
    Type: Grant
    Filed: April 8, 2011
    Date of Patent: May 29, 2012
    Assignee: Tomita Pharmaceutical Co., Ltd.
    Inventors: Yoji Marutani, Minoru Tomita, Hisaaki Hashimoto, Tomohide Koizumi, Kazuhiko Tamagawa, Akira Ookubo, Nozomu Hashimoto
  • Publication number: 20120018915
    Abstract: The present invention provides a powder for molding that reduces or prevents drawbacks such as unevenness and low fluidity when a mixed powder is used as a powder for molding. The present invention relates to powders for molding including particles in which each particle contains an inorganic component and a water-soluble organic polymer component and methods for producing the same.
    Type: Application
    Filed: February 26, 2010
    Publication date: January 26, 2012
    Applicant: TOMITA PHARMACEUTICAL CO., LTD.
    Inventors: Akira Ookubo, Tomohide Koizumi, Kazuma Tamura
  • Publication number: 20110186257
    Abstract: A method for manufacturing a mold, including steps of (a) expanding a powder mixture containing a water-soluble inorganic salt powder and a water-soluble organic polymer powder in a plane on a table and then selectively spraying a spray liquid containing at least one selected from a water-miscible organic solvent and water through a nozzle on this powder mixture layer to make a bonding strength among particles of the powder mixture in a sprayed region higher than that among particles of the powder mixture in an unsprayed region, (b) further expanding the powder mixture on the powder mixture layer after spraying and then selectively spraying the spray liquid through the nozzle on this powder mixture layer, (c) repeatedly conducting the step (b) over several times to form a mold shaped by the sprayed regions, and (d) taking out the mold.
    Type: Application
    Filed: April 8, 2011
    Publication date: August 4, 2011
    Applicant: TOMITA PHARMACEUTICAL CO., LTD.
    Inventors: Yoji Marutani, Minoru Tomita, Hisaaki Hashimoto, Tomohide Koizumi, Kazuhiko Tamagawa, Akira Ookubo, Nozomu Hashimoto
  • Patent number: 7942187
    Abstract: A method for manufacturing a mold, including steps of (a) expanding a powder mixture containing a water-soluble inorganic salt powder and a water-soluble organic polymer powder in a plane on a table and then selectively spraying a spray liquid containing at least one selected from a water-miscible organic solvent and water through a nozzle on this powder mixture layer to make a bonding strength among particles of the powder mixture in a sprayed region higher than that among particles of the powder mixture in an unsprayed region, (b) further expanding the powder mixture on the powder mixture layer after spraying and then selectively spraying the spray liquid through the nozzle on this powder mixture layer, (c) repeatedly conducting the step (b) over several times to form a mold shaped by the sprayed regions, and (d) taking out the mold.
    Type: Grant
    Filed: December 19, 2006
    Date of Patent: May 17, 2011
    Assignee: Tomita Pharmaceutical Co., Ltd.
    Inventors: Yoji Marutani, Minoru Tomita, Hisaaki Hashimoto, Tomohide Koizumi, Kazuhiko Tamagawa, Akira Ookubo, Nozomu Hashimoto
  • Publication number: 20110059247
    Abstract: [Object] To form a modeled object with high accuracy. [Solving Means] A powder transfer mechanism (16) laminates powder layers containing water-soluble powder as a main component one by one at a modeling portion (14). An inkjet line head (17) injects a water-based ink that dissolves the powder in an area of an uppermost layer of the powder layers laminated by the powder transfer mechanism (16), the area corresponding to a cross-sectional shape of a modeled object. Then, a heater (18) heats the powder for each layer of the powder layers. Further, the heater (18) heats the powder after the water-based ink is injected by the inkjet line head (17) or before the water-based ink is injected by the inkjet line head (17). The present invention can be applied to a modeling apparatus, for example.
    Type: Application
    Filed: May 14, 2009
    Publication date: March 10, 2011
    Applicants: Sony Corporation, Tomita Pharmaceutical Co., Ltd.
    Inventors: Junichi Kuzusako, Masanobu Yamamoto, Akira Ookubo, Toshihiro Kamewa, Tomohide Koizumi, Kazuma Tamura, Takeshi Matsui
  • Publication number: 20100260856
    Abstract: The present invention provides a core particle for a pharmaceutical preparation which features the requisite properties of a core particle, and which has enough chemical stability, and in which reactivity with the drug (an active pharmaceutical ingredient) is limited or prevented. More specifically, the present invention relates to a core particle wherein a film containing an active pharmaceutical ingredient can be formed on the surface thereof, and (1) the core particle comprises a pharmaceutically acceptable inorganic material, (2) the inorganic material is poorly soluble in water, and (3) pH of a solution of the inorganic material is 5 to 8.
    Type: Application
    Filed: September 8, 2008
    Publication date: October 14, 2010
    Applicant: TOMITA PHARMACEUTICAL CO., LTD.
    Inventors: Masashi Konishi, Shouichi Oonishi, Akira Ookubo, Masashi Yunoki, Ariumi Kawamoto, Kanako Hattori
  • Publication number: 20090008055
    Abstract: A method for manufacturing a mold, including steps of (a) expanding a powder mixture containing a water-soluble inorganic salt powder and a water-soluble organic polymer powder in a plane on a table and then selectively spraying a spray liquid containing at least one selected from a water-miscible organic solvent and water through a nozzle on this powder mixture layer to make a bonding strength among particles of the powder mixture in a sprayed region higher than that among particles of the powder mixture in an unsprayed region, (b) further expanding the powder mixture on the powder mixture layer after spraying and then selectively spraying the spray liquid through the nozzle on this powder mixture layer, (c) repeatedly conducting the step (b) over several times to form a mold shaped by the sprayed regions, and (d) taking out the mold.
    Type: Application
    Filed: December 19, 2006
    Publication date: January 8, 2009
    Applicant: TOMITA PHARMACEUTICAL CO., LTD.
    Inventors: Yoji Marutani, Minoru Tomita, Hisaaki Hashimoto, Tomohide Koizumi, Kazuhiko Tamagawa, Akira Ookubo, Nozomu Hashimoto
  • Publication number: 20010019727
    Abstract: A biocidal material comprising, as an active ingredient, a compound represented by General Formula (1)
    Type: Application
    Filed: December 13, 2000
    Publication date: September 6, 2001
    Applicant: Secretary, Agency of Industrial Science and Technology & Tomita Pharmaceutical Co., Ltd.
    Inventors: Yoji Makita, Osamu Ikai, Kenta Ooi, Akinari Sonoda, Masahito Taya, Motomu Nishioka, Akira Ookubo, Mikiko Mihara
  • Patent number: 6132624
    Abstract: A method for treating phosphate-containing waste water comprising treating phosphate-containing waste water with a metal hydroxide complex as a phosphate adsorbent represented by formula (1):M.sub.1-x.sup.2+ M.sub.x.sup.3+ (OH.sup.-).sub.2+x-y (A.sup.n-).sub.y/n(1)wherein M.sup.2+ represents at least one divalent metal ion selected from the group consisting of Mg.sup.2+, Ni.sup.2+, Zn.sup.2+, Fe.sup.2+, Ca.sup.2+ and Cu.sup.2+, M.sup.3+ represents at least one trivalent metal ion selected from the group consisting of Al.sup.3+ and Fe.sup.3+, A.sup.n- represents n-valent anion, 0.1.ltoreq.x.ltoreq.0.5, 0.1.ltoreq.y.ltoreq.0.5 and n is 1 or 2 to adsorb phosphate is provided.
    Type: Grant
    Filed: October 21, 1998
    Date of Patent: October 17, 2000
    Assignee: Tomita Pharmaceutical Co. LTD
    Inventors: Takashi Suzuki, Toshio Sato, Akira Ookubo, Tomohide Koizumi, Mikiko Mihara, Shouichi Oonishi
  • Patent number: 5976401
    Abstract: A method for treating phosphate-containing waste water comprising treating phosphate-containing waste water with a metal hydroxide complex as a phosphate adsorbent represented by the formula:M.sub.1-x.sup.2+ M.sub.x.sup.3+ (OH.sup.-).sub.2+x-y (A.sup.n-).sub.y/nwherein M.sup.2+ is at least one divalent metal ion selected from the group consisting of Mg.sup.2+, Ni.sup.2+, Zn.sup.2+, Fe.sup.2+, Ca.sup.2+ and Cu.sup.2+ ; M.sup.3+ is at least one divalent metal ion selected from the group consisting of Al.sup.3+ and Fe.sup.3+ ; A.sup.n- is an n-valent anion; x is in the range 0.1.ltoreq.x.ltoreq.0.5; y is in the range 0.1.ltoreq.y.ltoreq.0.5; and n is 1 or 2.
    Type: Grant
    Filed: August 6, 1997
    Date of Patent: November 2, 1999
    Assignee: Tomita Pharmaceutical Co., Ltd.
    Inventors: Takashi Suzuki, Toshio Sato, Akira Ookubo, Tomohide Koizumi, Mikiko Mihara, Shoichi Oonishi
  • Patent number: 4782311
    Abstract: A three terminal filter according to the present invention has a hot lead terminal provided with substantially U-shaped holding portions and a plate capacitor arranged between a pair of magnetic cores.
    Type: Grant
    Filed: May 27, 1987
    Date of Patent: November 1, 1988
    Assignee: Murata Manufacturing Co., Ltd.
    Inventor: Akira Ookubo