Patents by Inventor Akira Ookubo
Akira Ookubo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9636870Abstract: A powder transfer mechanism laminates powder layers containing water-soluble powder as a main component one by one at a modeling portion. An inkjet line head injects a water-based ink that dissolves the powder in an area of an uppermost layer of the powder layers laminated by the powder transfer mechanism, the area corresponding to a cross-sectional shape of a modeled object. Then, a heater heats the powder for each layer of the powder layers. Further, the heater heats the powder after the water-based ink is injected by the inkjet line head or before the water-based ink is injected by the inkjet line head. The present invention can be applied to a modeling apparatus, for example.Type: GrantFiled: May 14, 2009Date of Patent: May 2, 2017Assignee: Sony CorporationInventors: Junichi Kuzusako, Masanobu Yamamoto, Akira Ookubo, Toshihiro Kamewa, Tomohide Koizumi, Kazuma Tamura, Takeshi Matsui
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Patent number: 9149434Abstract: The present invention provides a core particle for a pharmaceutical preparation which features the requisite properties of a core particle, and which has enough chemical stability, and in which reactivity with the drug (an active pharmaceutical ingredient) is limited or prevented. More specifically, the present invention relates to a core particle wherein a film containing an active pharmaceutical ingredient can be formed on the surface thereof, and (1) the core particle comprises a pharmaceutically acceptable inorganic material, (2) the inorganic material is poorly soluble in water, and (3) pH of a solution of the inorganic material is 5 to 8.Type: GrantFiled: September 8, 2008Date of Patent: October 6, 2015Assignee: TOMITA PHARMACEUTICAL CO., LTD.Inventors: Masashi Konishi, Shouichi Oonishi, Akira Ookubo, Masashi Yunoki, Ariumi Kawamoto, Kanako Hattori
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Patent number: 8668852Abstract: The present invention provides a powder for molding that reduces or prevents drawbacks such as unevenness and low fluidity when a mixed powder is used as a powder for molding. The present invention relates to powders for molding including particles in which each particle contains an inorganic component and a water-soluble organic polymer component and methods for producing the same.Type: GrantFiled: February 26, 2010Date of Patent: March 11, 2014Assignee: Tomita Pharmaceutical Co., Ltd.Inventors: Akira Ookubo, Tomohide Koizumi, Kazuma Tamura
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Publication number: 20140030346Abstract: Provided is a core particle for a pharmaceutical preparation, capable of delivering a relatively large amount of a drug active ingredient, in particular, at a predetermined timing. This invention relates to a disintegrable core particle for a pharmaceutical preparation, which core particle is adapted for formation, on the particle surface, of a drug active ingredient-containing film, wherein (1) the core particle includes a pharmaceutically acceptable inorganic material and a disintegration promoting agent, (2) the inorganic material is poorly soluble in water, (3) the inorganic material has a content of from 50 to 95 wt %, and (4) the core particle has a bulk density of at least 0.6 g/mL.Type: ApplicationFiled: December 27, 2011Publication date: January 30, 2014Inventors: Masashi Konishi, Ariumi Kawamoto, Akira Ookubo, Masashi Yunoki
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Publication number: 20130059151Abstract: Provided is a magnesium oxide for pharmaceutical use that, when mixed with a drug that is unstable in acid, demonstrates high stabilizing effects on the drug while also demonstrating superior stability of the magnesium oxide per se. The magnesium oxide for pharmaceutical use is used by being mixed with a drug that is unstable in acid, and has a specific surface area as determined according to the BET method of 20 m2/g to 200 m2/g and a degree of activation of 40 Img/g to 200 Img/g.Type: ApplicationFiled: October 20, 2011Publication date: March 7, 2013Applicant: TOMITA PHARMACEUTICAL CO., LTD.Inventors: Masashi Konishi, Shouichi Oonishi, Akira Ookubo, Masashi Yunoki, Ariumi Kawamoto
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Patent number: 8186415Abstract: A method for manufacturing a mold, including steps of (a) expanding a powder mixture containing a water-soluble inorganic salt powder and a water-soluble organic polymer powder in a plane on a table and then selectively spraying a spray liquid containing at least one selected from a water-miscible organic solvent and water through a nozzle on this powder mixture layer to make a bonding strength among particles of the powder mixture in a sprayed region higher than that among particles of the powder mixture in an unsprayed region, (b) further expanding the powder mixture on the powder mixture layer after spraying and then selectively spraying the spray liquid through the nozzle on this powder mixture layer, (c) repeatedly conducting the step (b) over several times to form a mold shaped by the sprayed regions, and (d) taking out the mold.Type: GrantFiled: April 8, 2011Date of Patent: May 29, 2012Assignee: Tomita Pharmaceutical Co., Ltd.Inventors: Yoji Marutani, Minoru Tomita, Hisaaki Hashimoto, Tomohide Koizumi, Kazuhiko Tamagawa, Akira Ookubo, Nozomu Hashimoto
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Publication number: 20120018915Abstract: The present invention provides a powder for molding that reduces or prevents drawbacks such as unevenness and low fluidity when a mixed powder is used as a powder for molding. The present invention relates to powders for molding including particles in which each particle contains an inorganic component and a water-soluble organic polymer component and methods for producing the same.Type: ApplicationFiled: February 26, 2010Publication date: January 26, 2012Applicant: TOMITA PHARMACEUTICAL CO., LTD.Inventors: Akira Ookubo, Tomohide Koizumi, Kazuma Tamura
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Publication number: 20110186257Abstract: A method for manufacturing a mold, including steps of (a) expanding a powder mixture containing a water-soluble inorganic salt powder and a water-soluble organic polymer powder in a plane on a table and then selectively spraying a spray liquid containing at least one selected from a water-miscible organic solvent and water through a nozzle on this powder mixture layer to make a bonding strength among particles of the powder mixture in a sprayed region higher than that among particles of the powder mixture in an unsprayed region, (b) further expanding the powder mixture on the powder mixture layer after spraying and then selectively spraying the spray liquid through the nozzle on this powder mixture layer, (c) repeatedly conducting the step (b) over several times to form a mold shaped by the sprayed regions, and (d) taking out the mold.Type: ApplicationFiled: April 8, 2011Publication date: August 4, 2011Applicant: TOMITA PHARMACEUTICAL CO., LTD.Inventors: Yoji Marutani, Minoru Tomita, Hisaaki Hashimoto, Tomohide Koizumi, Kazuhiko Tamagawa, Akira Ookubo, Nozomu Hashimoto
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Patent number: 7942187Abstract: A method for manufacturing a mold, including steps of (a) expanding a powder mixture containing a water-soluble inorganic salt powder and a water-soluble organic polymer powder in a plane on a table and then selectively spraying a spray liquid containing at least one selected from a water-miscible organic solvent and water through a nozzle on this powder mixture layer to make a bonding strength among particles of the powder mixture in a sprayed region higher than that among particles of the powder mixture in an unsprayed region, (b) further expanding the powder mixture on the powder mixture layer after spraying and then selectively spraying the spray liquid through the nozzle on this powder mixture layer, (c) repeatedly conducting the step (b) over several times to form a mold shaped by the sprayed regions, and (d) taking out the mold.Type: GrantFiled: December 19, 2006Date of Patent: May 17, 2011Assignee: Tomita Pharmaceutical Co., Ltd.Inventors: Yoji Marutani, Minoru Tomita, Hisaaki Hashimoto, Tomohide Koizumi, Kazuhiko Tamagawa, Akira Ookubo, Nozomu Hashimoto
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Publication number: 20110059247Abstract: [Object] To form a modeled object with high accuracy. [Solving Means] A powder transfer mechanism (16) laminates powder layers containing water-soluble powder as a main component one by one at a modeling portion (14). An inkjet line head (17) injects a water-based ink that dissolves the powder in an area of an uppermost layer of the powder layers laminated by the powder transfer mechanism (16), the area corresponding to a cross-sectional shape of a modeled object. Then, a heater (18) heats the powder for each layer of the powder layers. Further, the heater (18) heats the powder after the water-based ink is injected by the inkjet line head (17) or before the water-based ink is injected by the inkjet line head (17). The present invention can be applied to a modeling apparatus, for example.Type: ApplicationFiled: May 14, 2009Publication date: March 10, 2011Applicants: Sony Corporation, Tomita Pharmaceutical Co., Ltd.Inventors: Junichi Kuzusako, Masanobu Yamamoto, Akira Ookubo, Toshihiro Kamewa, Tomohide Koizumi, Kazuma Tamura, Takeshi Matsui
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Publication number: 20100260856Abstract: The present invention provides a core particle for a pharmaceutical preparation which features the requisite properties of a core particle, and which has enough chemical stability, and in which reactivity with the drug (an active pharmaceutical ingredient) is limited or prevented. More specifically, the present invention relates to a core particle wherein a film containing an active pharmaceutical ingredient can be formed on the surface thereof, and (1) the core particle comprises a pharmaceutically acceptable inorganic material, (2) the inorganic material is poorly soluble in water, and (3) pH of a solution of the inorganic material is 5 to 8.Type: ApplicationFiled: September 8, 2008Publication date: October 14, 2010Applicant: TOMITA PHARMACEUTICAL CO., LTD.Inventors: Masashi Konishi, Shouichi Oonishi, Akira Ookubo, Masashi Yunoki, Ariumi Kawamoto, Kanako Hattori
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Publication number: 20090008055Abstract: A method for manufacturing a mold, including steps of (a) expanding a powder mixture containing a water-soluble inorganic salt powder and a water-soluble organic polymer powder in a plane on a table and then selectively spraying a spray liquid containing at least one selected from a water-miscible organic solvent and water through a nozzle on this powder mixture layer to make a bonding strength among particles of the powder mixture in a sprayed region higher than that among particles of the powder mixture in an unsprayed region, (b) further expanding the powder mixture on the powder mixture layer after spraying and then selectively spraying the spray liquid through the nozzle on this powder mixture layer, (c) repeatedly conducting the step (b) over several times to form a mold shaped by the sprayed regions, and (d) taking out the mold.Type: ApplicationFiled: December 19, 2006Publication date: January 8, 2009Applicant: TOMITA PHARMACEUTICAL CO., LTD.Inventors: Yoji Marutani, Minoru Tomita, Hisaaki Hashimoto, Tomohide Koizumi, Kazuhiko Tamagawa, Akira Ookubo, Nozomu Hashimoto
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Publication number: 20010019727Abstract: A biocidal material comprising, as an active ingredient, a compound represented by General Formula (1)Type: ApplicationFiled: December 13, 2000Publication date: September 6, 2001Applicant: Secretary, Agency of Industrial Science and Technology & Tomita Pharmaceutical Co., Ltd.Inventors: Yoji Makita, Osamu Ikai, Kenta Ooi, Akinari Sonoda, Masahito Taya, Motomu Nishioka, Akira Ookubo, Mikiko Mihara
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Patent number: 6132624Abstract: A method for treating phosphate-containing waste water comprising treating phosphate-containing waste water with a metal hydroxide complex as a phosphate adsorbent represented by formula (1):M.sub.1-x.sup.2+ M.sub.x.sup.3+ (OH.sup.-).sub.2+x-y (A.sup.n-).sub.y/n(1)wherein M.sup.2+ represents at least one divalent metal ion selected from the group consisting of Mg.sup.2+, Ni.sup.2+, Zn.sup.2+, Fe.sup.2+, Ca.sup.2+ and Cu.sup.2+, M.sup.3+ represents at least one trivalent metal ion selected from the group consisting of Al.sup.3+ and Fe.sup.3+, A.sup.n- represents n-valent anion, 0.1.ltoreq.x.ltoreq.0.5, 0.1.ltoreq.y.ltoreq.0.5 and n is 1 or 2 to adsorb phosphate is provided.Type: GrantFiled: October 21, 1998Date of Patent: October 17, 2000Assignee: Tomita Pharmaceutical Co. LTDInventors: Takashi Suzuki, Toshio Sato, Akira Ookubo, Tomohide Koizumi, Mikiko Mihara, Shouichi Oonishi
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Patent number: 5976401Abstract: A method for treating phosphate-containing waste water comprising treating phosphate-containing waste water with a metal hydroxide complex as a phosphate adsorbent represented by the formula:M.sub.1-x.sup.2+ M.sub.x.sup.3+ (OH.sup.-).sub.2+x-y (A.sup.n-).sub.y/nwherein M.sup.2+ is at least one divalent metal ion selected from the group consisting of Mg.sup.2+, Ni.sup.2+, Zn.sup.2+, Fe.sup.2+, Ca.sup.2+ and Cu.sup.2+ ; M.sup.3+ is at least one divalent metal ion selected from the group consisting of Al.sup.3+ and Fe.sup.3+ ; A.sup.n- is an n-valent anion; x is in the range 0.1.ltoreq.x.ltoreq.0.5; y is in the range 0.1.ltoreq.y.ltoreq.0.5; and n is 1 or 2.Type: GrantFiled: August 6, 1997Date of Patent: November 2, 1999Assignee: Tomita Pharmaceutical Co., Ltd.Inventors: Takashi Suzuki, Toshio Sato, Akira Ookubo, Tomohide Koizumi, Mikiko Mihara, Shoichi Oonishi
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Patent number: 4782311Abstract: A three terminal filter according to the present invention has a hot lead terminal provided with substantially U-shaped holding portions and a plate capacitor arranged between a pair of magnetic cores.Type: GrantFiled: May 27, 1987Date of Patent: November 1, 1988Assignee: Murata Manufacturing Co., Ltd.Inventor: Akira Ookubo