Patents by Inventor Akira Saikawa

Akira Saikawa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Sustained release compositions, process for producing the same and utilization thereof
    Patent number: 7388032
    Abstract: A sustained-release composition containing a hydroxynaphthoic acid salt of a biologically active substance and a biodegradable polymer, a method of its production, and a pharmaceutical composition containing said sustained-release composition.
    Type: Grant
    Filed: March 12, 2004
    Date of Patent: June 17, 2008
    Assignee: Takeda Pharmaceutical Company Limited
    Inventors: Akira Saikawa, Yasutaka Igari, Yoshio Hata, Kazumichi Yamamoto
  • Sustained-release preparation for AII antagonist, production and use thereof
    Patent number: 7294344
    Abstract: The present invention is to provide a sustained-release preparation which comprises a compound having angiotensin II antagonistic activity, its pro-drug or their salt, and a biodegradable polymer, and if necessary, a polyvalent metal, and which is highly stable and active and shows angiotensin II antagonistic activity while maintaining circadian rhythm of blood pressure for a long time.
    Type: Grant
    Filed: May 22, 2003
    Date of Patent: November 13, 2007
    Assignee: Takeda Pharmaceutical Company Limited
    Inventors: Yasutaka Igari, Akira Saikawa, Yoshiyuki Inada, Shigeru Kamei
  • Sustained release compositions, process for producing the same and utilization thereof
    Publication number: 20050025826
    Abstract: A sustained-release composition containing a hydroxynaphthoic acid salt of a biologically active substance and a biodegradable polymer, a method of its production, and a pharmaceutical composition containing said sustained-release composition.
    Type: Application
    Filed: March 12, 2004
    Publication date: February 3, 2005
    Inventors: Akira Saikawa, Yasutaka Igari, Yoshio Hata, Kazumichi Yamamoto
  • Sustained release compositions, process for producing the same and utilization thereof
    Patent number: 6740634
    Abstract: A sustained-release composition containing a hydroxynaphthoic acid salt of a biologically active substance and a biodegradable polymer, a method of its production, and a pharmaceutical composition containing said sustained-release composition.
    Type: Grant
    Filed: July 6, 2000
    Date of Patent: May 25, 2004
    Assignee: Takeda Chemical Industries, Ltd.
    Inventors: Akira Saikawa, Yasutaka Igari, Yoshio Hata, Kazumichi Yamamoto
  • Sustained-release preparation for AII antagonist, production and use thereof
    Publication number: 20030198676
    Abstract: The present invention is to provide a sustained-release preparation which comprises a compound having angiotensin II antagonistic activity, its pro-drug or their salt, and a biodegradable polymer, and if necessary, a polyvalent metal, and which is highly stable and active and shows angiotensin II antagonistic activity with maintaining circadian rhythm of blood pressure for a long time.
    Type: Application
    Filed: May 22, 2003
    Publication date: October 23, 2003
    Inventors: Yasutaka Igari, Akira Saikawa, Yoshiyuki Inada, Shigeru Kamei
  • Sustained-release preparation for AII antagonist, production and use thereof
    Patent number: 6589547
    Abstract: The present invention is to provide a sustained-release preparation which comprises a compound having angiotensin II antagonistic activity, its pro-drug or their salt, and a biodegradable polymer, and if necessary, a polyvalent metal, and which is highly stable and active and shows angiotensin II antagonistic activity while maintaining circadian rhythm of blood pressure for a long time.
    Type: Grant
    Filed: August 9, 2000
    Date of Patent: July 8, 2003
    Assignee: Takeda Chemical Industries, Ltd.
    Inventors: Yasutaka Igari, Akira Saikawa, Yoshiyuki Inada, Shigeru Kamei
  • Matrix for sustained-release preparation
    Patent number: 5665394
    Abstract: The present invention relates to a matrix for sustained-release preparation comprising an ester formed at a terminal carboxyl group of a straight-chain polyester which essentially consists of an .alpha.-hydroxymonocarboxylic acid. The matrix is stable to light, heat, moisture, coloring etc., and is of low toxicity. The sustained-release preparation produced by using the ester of the present invention offers stable drug release over an extended period of time, ensuring sustained stable effect. Furthermore, the sustained-release preparation does not show excess drug release just after administration.
    Type: Grant
    Filed: September 30, 1996
    Date of Patent: September 9, 1997
    Assignees: Takeda Chemical Industries, Ltd., Wako Purechemical Industries, Ltd.
    Inventors: Yasutaka Igari, Akira Saikawa, Kayoko Okamoto, Shigeru Kamei, Masahisa Oka, Atsunori Sano
  • Matrix for sustained-release preparation
    Patent number: 5594091
    Abstract: The present invention relates to a matrix for sustained-release preparation comprising an ester formed at a terminal carboxyl group of a straight-chain polyester which essentially consists of an .alpha.-hydroxymonocarboxylic acid. The matrix is stable to light, heat, moisture, coloring etc., and is of low toxicity. The sustained-release preparation produced by using the ester of the present invention offers stable drug release over an extended period of time, ensuring sustained stable effect. Furthermore, the sustained-release preparation does not show excess drug release just after administration.
    Type: Grant
    Filed: February 21, 1995
    Date of Patent: January 14, 1997
    Assignee: Takeda Chemical Industries, Ltd.
    Inventors: Yasutaka Igari, Akira Saikawa, Kayoko Okamoto, Shigeru Kamei, Masahisa Oka, Atsunori Sano