Patents by Inventor Alan Black
Alan Black has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240131047Abstract: In one aspect disclosed herein are small molecule inhibitors of CD38 and their use in treating, inhibiting, decreasing, reducing, ameliorating and/or preventing graft versus host disease, ischemia reperfusion injury, graft rejection, inflammatory injury to a graft or a graft recipient. Additionally, disclosed herein are methods of inhibiting CD38 pathway and activity comprising contacting a cell expressing CD38 or administering to a subject in need of CD38 inhibition, any of the small molecule CD38 inhibitors disclosed herein.Type: ApplicationFiled: February 8, 2022Publication date: April 25, 2024Inventors: Sylvester Michael BLACK, Bryan Alan WHITSON, Blake Robert PETERSON, Austin SCHENK
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Patent number: 11180815Abstract: This invention relates to prognostic signatures, and compositions and methods for determining the prognosis of cancer in a patient, particularly for colorectal cancer. Specifically, this invention relates to the use of genetic markers for the prediction of the prognosis of cancer, such as colorectal cancer based on signatures of genetic markers. In various aspects, the invention relates to a method of predicting the likelihood of long-term survival of a cancer patient, a method of determining a treatment regime for a cancer patient, a method of preparing a treatment modality for a cancer patient, among other methods as well as kits and devices for carrying out these methods.Type: GrantFiled: August 27, 2019Date of Patent: November 23, 2021Assignee: PACIFIC EDGE LIMITEDInventors: Hjalmar Nekarda, Jan Friederichs, Bernhard Holzmann, Robert Rosenberg, Anthony Edmund Reeve, Michael Alan Black, John Lindsay McCall, Yu-Hsin Lin, Robert Craig Pollock
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Patent number: 10726869Abstract: An apparatus for changing a record comprising a record changing fork comprising first and second spaced apart tines arranged in a record plane and extending from a fork base to a fork mouth, each tine comprising a groove extending from the fork mouth at least part way to the fork base, the grooves being arranged to hold a record therebetween in the record plane; at least one tine comprising a resiliently deformable record gate, the record gate being adapted to prevent sliding of a record in the grooves past the record gate unless the record is slid with a force exceeding a threshold force; at least one shelf adapted to support a record, the width of the shelf being less than the separation between the tines; and, a control mechanism connected to the record changing fork.Type: GrantFiled: February 12, 2018Date of Patent: July 28, 2020Assignee: Sound Leisure LimitedInventor: Alan Black
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Publication number: 20200140955Abstract: This invention relates to prognostic signatures, and compositions and methods for determining the prognosis of cancer in a patient, particularly for colorectal cancer. Specifically, this invention relates to the use of genetic markers for the prediction of the prognosis of cancer, such as colorectal cancer based on signatures of genetic markers. In various aspects, the invention relates to a method of predicting the likelihood of long-term survival of a cancer patient, a method of determining a treatment regime for a cancer patient, a method of preparing a treatment modality for a cancer patient, among other methods as well as kits and devices for carrying out these methods.Type: ApplicationFiled: August 27, 2019Publication date: May 7, 2020Applicant: Pacific Edge LimitedInventors: Hjalmar Nekarda, Jan Friederichs, Bernhard Holzmann, Robert Rosenberg, Anthony Edmund Reeve, Michael Alan Black, John Lindsay McCall, Yu-Hsin Lin, Robert Craig Pollock
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Publication number: 20200043523Abstract: An apparatus for changing a record comprising a record changing fork comprising first and second spaced apart tines arranged in a record plane and extending from a fork base to a fork mouth, each tine comprising a groove extending from the fork mouth at least part way to the fork base, the grooves being arranged to hold a record therebetween in the record plane; at least one tine comprising a resiliently deformable record gate, the record gate being adapted to prevent sliding of a record in the grooves past the record gate unless the record is slid with a force exceeding a threshold force; at least one shelf adapted to support a record, the width of the shelf being less than the separation between the tines; and, a control mechanism connected to the record changing fork.Type: ApplicationFiled: February 12, 2018Publication date: February 6, 2020Inventor: Alan Black
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Patent number: 10422005Abstract: This invention relates to prognostic signatures, and compositions and methods for determining the prognosis of cancer in a patient, particularly for colorectal cancer. Specifically, this invention relates to the use of genetic markers for the prediction of the prognosis of cancer, such as colorectal cancer, based on signatures of genetic markers. In various aspects, the invention relates to a method of predicting the likelihood of long-term survival of a cancer patient, a method of determining a treatment regime for a cancer patient, a method of preparing a treatment modality for a cancer patient, among other methods as well as kits and devices for carrying out these methods.Type: GrantFiled: June 20, 2008Date of Patent: September 24, 2019Assignee: PACIFIC EDGE LIMITEDInventors: Hjalmar Nekarda, Jan Friederichs, Bernhard Holzmann, Robert Rosenberg, Anthony Edmund Reeve, Michael Alan Black, John Lindsay McCall, Yu-Hsin Lin, Robert Craig Pollock
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Patent number: 10266902Abstract: The invention relates to prognostic markers and prognostic signatures, and compositions and methods for determining the prognosis of cancer in a patient, particularly for melanoma. Specifically, the invention relates to the use of genetic and protein markers for the prediction of the risk of progression of a cancer, such as melanoma, based on markers and signatures of markers. In various aspects, the invention provides methods, compositions, kits, and devices based on prognostic cancer markers, specifically melanoma prognostic markers, to aid in the prognosis and treatment of cancer.Type: GrantFiled: December 27, 2016Date of Patent: April 23, 2019Assignees: PACIFIC EDGE LIMITED, LUDWIG INSTITUTE FOR CANCER RESEARCHInventors: Michael Alan Black, Jonathan Cebon, Parry John Guilford, Thomas John
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Publication number: 20170107583Abstract: The invention relates to prognostic markers and prognostic signatures, and compositions and methods for determining the prognosis of cancer in a patient, particularly for melanoma. Specifically, the invention relates to the use of genetic and protein markers for the prediction of the risk of progression of a cancer, such as melanoma, based on markers and signatures of markers. In various aspects, the invention provides methods, compositions, kits, and devices based on prognostic cancer markers, specifically melanoma prognostic markers, to aid in the prognosis and treatment of cancer.Type: ApplicationFiled: December 27, 2016Publication date: April 20, 2017Applicants: Pacific Edge Limited, Ludwig Institute for Cancer ResearchInventors: Michael Alan Black, Jonathan Cebon, Parry John Guilford, Thomas John
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Patent number: 9534258Abstract: The invention relates to prognostic markers and prognostic signatures, and compositions and methods for determining the prognosis of cancer in a patient, particularly for melanoma. Specifically, the invention relates to the use of genetic and protein markers for the prediction of the risk of progression of a cancer, such as melanoma, based on markers and signatures of markers. In various aspects, the invention provides methods, compositions, kits, and devices based on prognostic cancer markers, specifically melanoma prognostic markers, to aid in the prognosis and treatment of cancer.Type: GrantFiled: August 29, 2014Date of Patent: January 3, 2017Assignee: PACIFIC EDGE LIMITEDInventors: Michael Alan Black, Jonathan Cebon, Parry John Guilford, Thomas John
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Publication number: 20160068916Abstract: This invention relates to prognostic signatures, and compositions and methods for determining the prognosis of cancer in a patient, particularly for colorectal cancer. Specifically, this invention relates to the use of genetic markers for the prediction of the prognosis of cancer, such as colorectal cancer, based on signatures of genetic markers. In various aspects, the invention relates to a method of predicting the likelihood of long-term survival of a cancer patient, a method of determining a treatment regime for a cancer patient, a method of preparing a treatment modality for a cancer patient, among other methods as well as kits and devices for carrying out these methods.Type: ApplicationFiled: September 21, 2015Publication date: March 10, 2016Applicant: Pacific Edge LimitedInventors: Hjalmar Nekarda, Jan Friederichs, Bernhard Holzmann, Robert Rosenberg, Anthony Edmund Reeve, Michael Alan Black, John Lindsay McCall, Yu-Hsin Lin, Robert Craig Pollock
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Publication number: 20150031578Abstract: The invention relates to prognostic markers and prognostic signatures, and compositions and methods for determining the prognosis of cancer in a patient, particularly for melanoma. Specifically, the invention relates to the use of genetic and protein markers for the prediction of the risk of progression of a cancer, such as melanoma, based on markers and signatures of markers. In various aspects, the invention provides methods, compositions, kits, and devices based on prognostic cancer markers, specifically melanoma prognostic markers, to aid in the prognosis and treatment of cancer.Type: ApplicationFiled: August 29, 2014Publication date: January 29, 2015Applicants: PACIFIC EDGE LIMITED, LUDWIG INSTITUTE FOR CANCER RESEARCHInventors: MICHAEL ALAN BLACK, JONATHAN CEBON, PARRY JOHN GUILFORD, THOMAS JOHN
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Patent number: 8822149Abstract: The invention relates to prognostic markers and prognostic signatures, and compositions and methods for determining the prognosis of cancer in a patient, particularly for melanoma. Specifically, the invention relates to the use of genetic and protein markers for the prediction of the risk of progression of a cancer, such as melanoma, based on markers and signatures of markers. In various aspects, the invention provides methods, compositions, kits, and devices based on prognostic cancer markers, specifically melanoma prognostic markers, to aid in the prognosis and treatment of cancer.Type: GrantFiled: November 23, 2009Date of Patent: September 2, 2014Assignee: Pacific Edge LimitedInventors: Michael Alan Black, Jonathan Cebon, Parry John Guilford, Thomas John
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Publication number: 20100136553Abstract: The invention relates to prognostic markers and prognostic signatures, and compositions and methods for determining the prognosis of cancer in a patient, particularly for melanoma. Specifically, the invention relates to the use of genetic and protein markers for the prediction of the risk of progression of a cancer, such as melanoma, based on markers and signatures of markers. In various aspects, the invention provides methods, compositions, kits, and devices based on prognostic cancer markers, specifically melanoma prognostic markers, to aid in the prognosis and treatment of cancer.Type: ApplicationFiled: November 23, 2009Publication date: June 3, 2010Inventors: Michael Alan Black, Jonathan Cebon, Parry John Guilford, Thomas John
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Publication number: 20090181384Abstract: This invention relates to prognostic signatures, and compositions and methods for determining the prognosis of cancer in a patient, particularly for colorectal cancer. Specifically, this invention relates to the use of genetic markers for the prediction of the prognosis of cancer, such as colorectal cancer, based on signatures of genetic markers. In various aspects, the invention relates to a method of predicting the likelihood of long-term survival of a cancer patient, a method of determining a treatment regime for a cancer patient, a method of preparing a treatment modality for a cancer patient, among other methods as well as kits and devices for carrying out these methods.Type: ApplicationFiled: June 20, 2008Publication date: July 16, 2009Inventors: Hjalmar Nekarda, Jan Friederichs, Bernhard Holzmann, Robert Rosenberg, Anthony Edmund Reeve, Michael Alan Black, John Lindsay McCall, Yu-Hsin Lin, Robert Craig Pollock
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Publication number: 20090000189Abstract: A modular planter system comprises a plurality of vertically spaced apart troughs, at least one longitudinally extending support member adapted to position the troughs one above another, and one or more planter inserts configured for insertion into a trough.Type: ApplicationFiled: June 27, 2007Publication date: January 1, 2009Inventor: Alan Black
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Patent number: 5826375Abstract: A modular planter system comprising: a plurality of troughs having a drainage conduit extending vertically upwards and downwards from the bottom of the trough; a reservoir, a support member between adjacent troughs; kit for assembling the modular planter system.Type: GrantFiled: June 7, 1996Date of Patent: October 27, 1998Inventor: Alan Black
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Patent number: 5715756Abstract: An amusement ride attraction has an anti-roll back track with stops or cross bolts covered by a continuous brush material. A vehicle such as a roller coaster car or water flume boat has an anti-roll back pawl which rides above the fiber material on skis, when the vehicle moves forward. If the vehicle begins to move backward, the skis move downwardly through the brush material and the pawl engages a stop on the track, to prevent further reverse movement. The brush material prevents the pawl from banging over each of the stops on the track, thereby reducing noise and wear.Type: GrantFiled: June 7, 1996Date of Patent: February 10, 1998Assignee: Universal Studios, Inc.Inventors: Frank K. Weigand, Alan Black, Nick Drobnis