Patents by Inventor Alan E. Kligerman

Alan E. Kligerman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9861647
    Abstract: Calcium glycerophosphate is found to be effective in treating and preventing a disease, disorder and/or condition of the respiratory system. The disease, disorder and/or condition is related to an obstructive or a restrictive condition of the respiratory airway.
    Type: Grant
    Filed: May 11, 2016
    Date of Patent: January 9, 2018
    Assignee: Prelief, Inc.
    Inventors: Alan E. Kligerman, Margaret T. Weis
  • Publication number: 20160250235
    Abstract: Calcium glycerophosphate is found to be effective in treating and preventing a disease, disorder and/or condition of the respiratory system. The disease, disorder and/or condition is related to an obstructive or a restrictive condition of the respiratory airway.
    Type: Application
    Filed: May 11, 2016
    Publication date: September 1, 2016
    Inventors: Alan E. KLIGERMAN, Margaret T. WEIS
  • Patent number: 9358242
    Abstract: Calcium glycerophosphate is found to be effective in treating and preventing a disease, disorder and/or condition of the respiratory system. The disease, disorder and/or condition is related to an obstructive or a restrictive condition of the respiratory airway.
    Type: Grant
    Filed: March 1, 2010
    Date of Patent: June 7, 2016
    Assignee: Prelief Inc.
    Inventors: Alan E. Kligerman, Margaret T. Weis
  • Publication number: 20150374725
    Abstract: Methods and compositions for treating and preventing intestinal injury are described. In particular, methods and delayed-release enteric coated compositions of glycerophosphate salts for treating and preventing an intestinal injury, such as exercise-induced intestinal injury, intestinal injury induced or aggravated by ingestion of a nonsteroidal anti-inflammatory drug (NSAID), or exercise-induced intestinal injury aggravated by an NSAID, are described. Orally or nasally administering a therapeutically effective amount of a glycerophosphate salt, particularly calcium glycerophosphate, to a subject engaging in exercise, particularly a subject engaging in exercise and ingesting a NSAID for the treatment or prevention of musculoskeletal pain resulting from exercise, reduces exercise-induced intestinal injury, particularly exercise-induced intestinal injury aggravated by the NSAID. A method of increasing tight junction integrity in a subject in need thereof is also described.
    Type: Application
    Filed: February 20, 2014
    Publication date: December 31, 2015
    Inventors: Alan E. KLIGERMAN, Margaret T. WEIS
  • Publication number: 20140363486
    Abstract: Glycerophosphate salts have been found to hasten the healing of wounds and minimize the formation of scars, particularly when it is first applied to a wound about 0 to about 7 days after the wound is inflicted. Methods and compositions are provided for treating wounds using a composition comprising an effective amount of glycerophosphate salt. In particular, methods are provided for treating wounds using calcium glycerophosphate (CGP), for accelerating the healing process, reducing pain and scar formation, and for the cosmetic reducing, excision, erasure and/or complete repair of scars (scar revision).
    Type: Application
    Filed: July 30, 2014
    Publication date: December 11, 2014
    Inventor: Alan E. KLIGERMAN
  • Patent number: 8802073
    Abstract: Glycerophosphate salts have been found to hasten the healing of wounds and minimize the formation of scars, particularly when it is first applied to a wound about 0 to about 7 days after the wound is inflicted. Methods and compositions are provided for treating wounds using a composition comprising an effective amount of glycerophosphate salt. In particular, methods are provided for treating wounds using calcium glycerophosphate (CGP), for accelerating the healing process, reducing pain and scar formation, and for the cosmetic reducing, excision, erasure and/or complete repair of scars (scar revision).
    Type: Grant
    Filed: November 12, 2008
    Date of Patent: August 12, 2014
    Assignee: Prelief Inc.
    Inventor: Alan E. Kligerman
  • Publication number: 20140220094
    Abstract: Glycerophosphate salts have been found to drastically improve a laparoscopic surgery by reducing the inflammatory response inflicted by the surgery and enhancing wound healing. Methods and devices for improving the laparoscopic surgery using a composition comprising an effective amount of a glycerophosphate salt are described.
    Type: Application
    Filed: April 10, 2014
    Publication date: August 7, 2014
    Applicant: PRELIEF INC.
    Inventors: Alan E. KLIGERMAN, Joseph V. DITROLIO
  • Publication number: 20100305071
    Abstract: Glycerophosphate salts have been found to hasten the healing and rapid scaling of lesions of the mouth. Methods are provided for improving healing of an oral lesion or preventing diseases or conditions related to an oral lesion using a glycerophosphate salt. In particular, methods are provided for preventing diseases or conditions related to an oral lesion using calcium glycerophosphate (CGP).
    Type: Application
    Filed: August 28, 2008
    Publication date: December 2, 2010
    Applicant: PRELIEF INC.
    Inventor: Alan E. Kligerman
  • Publication number: 20100255070
    Abstract: A composition for preventing, mitigating, and alleviating irritation and skin trauma is described. The composition contains calcium glycerophosphate and at least one skin compatible, film-forming component. The composition may be applied to the skin prior to application of an adhesive tape to reduce damage to the skin which is inflicted upon removal of the tape by forming a film on the skin. Upon removal of the adhesive tape from the skin, the film, rather than skin cells, is removed with the tape. The calcium glycerophosphate component of the composition also penetrates the skin and serves to alleviate any damage which may be inflicted on the skin. The composition may also be applied to the skin to prevent subsequent irritation, such as irritation inflicted by contact with poison ivy, clothing, jewelry, insect bites, a prosthetic, etc. A medical dressing which contains the composition is also included.
    Type: Application
    Filed: May 22, 2008
    Publication date: October 7, 2010
    Applicant: PRELIEF INC.
    Inventor: Alan E. Kligerman
  • Publication number: 20100239645
    Abstract: Glycerophosphate salts have been found to hasten the healing of wounds and minimize the formation of scars, particularly when it is first applied to a wound about 0 to about 7 days after the wound is inflicted. Methods and compositions are provided for treating wounds using a composition comprising an effective amount of glycerophosphate salt. In particular, methods are provided for treating wounds using calcium glycerophosphate (CGP), for accelerating the healing process, reducing pain and scar formation, and for the cosmetic reducing, excision, erasure and/or complete repair of scars (scar revision).
    Type: Application
    Filed: November 12, 2008
    Publication date: September 23, 2010
    Applicant: PRELIEF INC.
    Inventor: Alan E. Kligerman
  • Publication number: 20100210600
    Abstract: Glycerophosphate salts have been found to drastically improve the treatment of urogenital disorders such as urethral strictures and vaginal atrophy. Methods, devices and kits are described for treating urogenital disorders using a composition comprising an effective amount of a glycerophosphate salt.
    Type: Application
    Filed: February 18, 2010
    Publication date: August 19, 2010
    Applicant: PRELIEF INC.
    Inventors: Alan E. KLIGERMAN, Joseph V. DITROLIO
  • Publication number: 20100158819
    Abstract: Calcium glycerophosphate is found to be effective in treating and preventing a disease, disorder and/or condition of the respiratory system. The disease, disorder and/or condition is related to an obstructive or a restrictive condition of the respiratory airway.
    Type: Application
    Filed: March 1, 2010
    Publication date: June 24, 2010
    Applicant: PRELIEF INC.
    Inventors: Alan E. Kligerman, Margaret T. Weis
  • Publication number: 20100041630
    Abstract: Glycerophosphate salts have been found to mitigate the syndromes or conditions of discomfort associated with inflammation. Therefore, methods are provided for treating or preventing an inflammatory condition using a glycerophosphate salt. In particular, methods are provided for treating or preventing an inflammatory condition using calcium glycerophosphate (CGP).
    Type: Application
    Filed: February 13, 2008
    Publication date: February 18, 2010
    Applicant: PRELIEF INC.
    Inventor: Alan E. Kligerman
  • Publication number: 20100029590
    Abstract: Glycerophosphate salts have been found to mitigate the syndromes or conditions of discomfort associated with hem-orrhagic cystitis. Therefore, methods are provided for treating or preventing the syndromes or conditions of discomfort associated with hemorrhagic cystitis using a glycerophosphate salt, hi particular, methods are provided for treating or preventing the syndromes or conditions of discomfort associated with hemorrhagic cystitis using calcium glycerophosphate (CGP).
    Type: Application
    Filed: February 13, 2008
    Publication date: February 4, 2010
    Applicant: PRELIEF INC.
    Inventor: Alan E. Kligerman
  • Publication number: 20090197840
    Abstract: A skin treatment composition is provided which contains calcium glycerophosphate and a fatty acid source derived from an animal or a vegetable. The composition enhances skin cell proliferation and growth and repair of damage to skin cells. Methods for enhancing skin cell repair, proliferation, and growth and for enhancing ceramide synthesis involve topically applying to the skin a composition containing calcium glycerophosphate and a fatty acid source derived from an animal or a vegetable.
    Type: Application
    Filed: March 18, 2009
    Publication date: August 6, 2009
    Applicant: PRELIEF INC.
    Inventors: Alan E. KLIGERMAN, Margaret WEIS
  • Patent number: 7402323
    Abstract: A skin treatment composition containing ionic calcium and a dermatologically acceptable water-soluble, water-miscible or water-based carrier is provided for treating a skin condition in a mammal, such as dry skin, dry scalp, a burn, sunburn, irritation or minor wound. The ionic calcium is preferably present as the water soluble calcium glycerophosphate salt. The composition may be present in a formulation such as bar soap, liquid soap, bath, lotion, cream, gel, or ointment, and may also be useful for stimulating more youthful skin cells and for improving the appearance of the skin. Methods for treating skin conditions and for accelerating cellular repair include topically applying to the skin an effective amount of ionic calcium, preferably as calcium glycerophosphate, and an ?-hydroxy acid such as lactic acid.
    Type: Grant
    Filed: August 12, 2003
    Date of Patent: July 22, 2008
    Assignee: AkPharma, Inc.
    Inventors: Alan E. Kligerman, Sarah Finnegan, Margaret Weis
  • Publication number: 20080107743
    Abstract: A skin treatment composition is provided which contains calcium glycerophosphate and a fatty acid source derived from an animal or a vegetable. The composition enhances skin cell proliferation and growth and repair of damage to skin cells. Methods for enhancing skin cell repair, proliferation, and growth and for enhancing ceramide synthesis involve topically applying to the skin a composition containing calcium glycerophosphate and a fatty acid source derived from an animal or a vegetable.
    Type: Application
    Filed: November 2, 2007
    Publication date: May 8, 2008
    Applicant: AKPHARMA INC.
    Inventors: Alan E. Kligerman, Margaret Weis
  • Publication number: 20040037766
    Abstract: A skin treatment composition containing ionic calcium and a dermatologically acceptable water-soluble, water-miscible or water-based carrier is provided for treating a skin condition in a mammal, such as dry skin, dry scalp, a burn, sunburn, irritation or minor wound. The ionic calcium is preferably present as the water soluble calcium glycerophosphate salt. The composition may be present in a formulation such as bar soap, liquid soap, bath, lotion, cream, gel, or ointment, and may also be useful for stimulating more youthful skin cells and for improving the appearance of the skin. Methods for treating skin conditions and for accelerating cellular repair include topically applying to the skin an effective amount of ionic calcium, preferably as calcium glycerophosphate, and an &agr;-hydroxy acid such as lactic acid.
    Type: Application
    Filed: August 12, 2003
    Publication date: February 26, 2004
    Applicant: AkPharma, Inc.
    Inventors: Alan E. Kligerman, Sarah Finnegan, Margaret Weis
  • Patent number: 6447754
    Abstract: Methods of freshening and reducing acidity in both the mouth and the throat of a mammal, such as a human, include taking into the mouth an aqueous solution of calcium glycerophosphate (CGP) in an amount effective to reduce the acidity, maintaining the solution in the mouth, and swallowing the aqueous solution in order to freshen and reduce acidity in both the mouth and the throat. The methods are convenient for use at any place and any time and do not have the inconveniences and limitations of conventional oral rinse or oral hygiene methods, such as the need for proximity to private or public plumbing facilities. Swallowable oral rinse compositions include an aqueous solution of CGP in an amount effective to freshen and reduce acidity in both the mouth and the throat of a mammal, such as a human, and at least one of a sweetening agent and a flavoring agent. The oral rinse compositions comprising CGP are preferably safe for ingestion even by children.
    Type: Grant
    Filed: January 24, 2000
    Date of Patent: September 10, 2002
    Assignee: AkPharma Inc.
    Inventors: Alan E. Kligerman, Sarah Rogers
  • Publication number: 20020106366
    Abstract: A composition is provided for ingestion by mammals for in vivo conversion of alpha-D-galactoside comprising an amount of alpha-galactosidase effective to hydrolyze alpha-D-galactoside to D-galactose, and non-toxic, ingestible excipients(s) for said alpha-galactrosidase. Gastric distress in mammals due to ingestion of foods containing alpha-D-galactoside may be reduced by ingesting the foregoing composition of alpha-galactosidase and non-toxic, ingestible excipient contemporaneously with the ingestion of said food in an amount effective to hydrolyze the alpha-D-galactoside to D-galactose.
    Type: Application
    Filed: February 14, 2002
    Publication date: August 8, 2002
    Applicant: SmithKline Beecham Corporation
    Inventor: Alan E. Kligerman