Abstract: A method of removing an antigenic substance from a fluid comprises(1) forming a ternary complex by the interaction of(a) the antigenic substance,(b) a first antibody which contains a kappa chain and which binds to the antigenic substance, and(c) a second antibody which binds to the kappa chain of the first antibody, said second antibody being immobilized on a solid phase carrier, and(2) separating the fluid from the solid phase carrier.

Abstract: Proteases are separated from fluids by contacting a fluid with a porous inorganic material such as porous titania particles to sorb the protease and then eluting the protease from the inorganic material. Proteases which may be separated are the sulphydryl proteases including papain, stem bromelain, fruit bromelain, ficin, calotropain and mexicain. Elution of the protease may be carried out with plant juice from which protease has previously been removed. The porous inorganic material is preferably that prepared by mixing a finely divided sorptive inorganic material with a solid fugitive additive and a solvent to dissolve the fugitive, forming discrete particles from the resultant mixture and heating the particles to remove the solvent and fugitive to produce discrete particles of the inorganic material for contacting with the fluid.

Abstract: A process is disclosed for the separation of macromolecules from a fluid substance containing the macromolecules.The process comprises contacting the fluid substance with discrete porous particles having an interconnected porosity throughout which provides an extended surface area and a pore structure such as will allow the macromolecules to permeate the particles and be sorbed, the discrete porous particles being selected such that a proportion thereof have acidic surfaces for contacting the macromolecules in the fluid substance and a proportion thereof have basic surfaces for contacting the macromolecules in the fluid substance.A process for the separation of protein from milk whey solution is also disclosed.