Patents by Inventor Alan W. J. Stuttle

Alan W. J. Stuttle has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Reagent for tumor imaging and therapy
    Patent number: 5628979
    Abstract: Novel oligopeptides are disclosed for in vivo tumor imaging and therapy. The novel oligopeptides are oligopeptides containing from 4 to 50 peptide units containing as a characteristic triplet therein the amino acid sequence leu-asp-val (LDV), which triplet provides the oligopeptide with a strong in vivo binding affinity for LDV binding sites on tumors and other tissues. For diagnostic purposes the oligopeptides are labelled with a radioactive label, e.g. .sup.125 I, whilst for therapeutic purposes the oligopeptides are chemically linked to or conjugated with a cytotoxin, such as the ricin A-chain.
    Type: Grant
    Filed: June 13, 1994
    Date of Patent: May 13, 1997
    Assignee: Antisoma Limited
    Inventor: Alan W. J. Stuttle
  • Synthetic peptides for use in tumor detection
    Patent number: 5395609
    Abstract: Radioactively labelled peptides comprising oligopeptides of from 3 to 10 peptide units and containing the sequence RGD and particularly the oligopeptides RGDSY and RGDFY, are disclosed as in vivo thrombus, tumor or CAM markers for the in vivo diagnosis and detection of thrombi, tumors or CAM in mammals.
    Type: Grant
    Filed: May 3, 1993
    Date of Patent: March 7, 1995
    Assignee: Antisoma Limited
    Inventor: Alan W. J. Stuttle