Patents by Inventor Alasdair T. Glen
Alasdair T. Glen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 5334722Abstract: Fungicidal compounds of formula (I): ##STR1## in which X and Y are independently O or S, and A and R.sup.1 to R.sup.4 have various specified values.Type: GrantFiled: April 7, 1992Date of Patent: August 2, 1994Assignee: Imperial Chemical Industries PLCInventors: Patrick J. Crowley, Alasdair T. Glen, Rosamund A. Spence, Kevin R. Lawson
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Patent number: 5280044Abstract: Fungicidal compounds of the formula (I): ##STR1## in which A and B are independently H, fluoro, chloro, bromo, C.sub.1-4 alkyl, C.sub.1-4 alkoxy or halo(C.sub.1-4)alkyl provided that both are not H; D and E are independently H or fluoro; R.sup.1 is H, C.sub.1-4 alkyl or C.sub.1-4 alkoxy; R.sup.2 is CC.sub.1-4 alkyl, C.sub.1-4 alkoxy or optionally substituted phenyl, or R.sup.1 and R.sup.2 together with the nitrogen atom to which they are attached join to form a morpholine, piperidine, pyrrolidine or azetidine ring which is optionally substituted with C.sub.1-4 alkyl; R.sup.3 is H; R.sup.4 is trichloromethyl, C.sub.2-8 alkyl (optionally substituted with halogen, C.sub.1-8 alkoxy or R'S(O) in which R' is C.sub.1-4 alkyl, C.sub.2-4 alkenyl or C.sub.2-4 alkynyl and n is 0, 1 or 2), cyclopropyl (optionally substituted with halogen or C.sub.1-4 alkyl), C.sub.2-8 alkenyl, C.sub.2-8 alkynyl, C.sub.1-8 alkoxy, mono- or di(C.sub.1-4)alkyl- amino or the group, R"ON.dbd.C(CN) in which R" is C.sub.1-4 alkyl, or R.sup.Type: GrantFiled: December 31, 1990Date of Patent: January 18, 1994Assignee: Imperial Chemical Industries PLCInventors: Patrick J. Crowley, Alasdair T. Glen, Rosamund A. Spence
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Patent number: 4999381Abstract: Fungicidal compounds of the formula (I): ##STR1## in which A and B are independently H, fluoro, chloro, bromo, C.sub.1-4 alkyl, C.sub.1-4, alkoxy or halo (C.sub.1-4) alkyl provided that both are not H; D and E are independently H or fluoro; F.sup.1 is H, C.sub.1-4 alkyl or C.sub.1-4 akloxy; R.sup.2 is C.sub.1-4 alkyl, C.sub.1-4 alkoxy or optionally substituted phenyl, or R.sup.1 and R.sup.2 together with the nitrogen atom to which they are attached join to form a morpholine, piperidine, pyrrolidine or azetidine ring which is optionally substituted with C.sub.1-4 alkyl; R.sup.3 is H; R.sup.4 is trichloromethyl, C.sub.2-8 alkyl (optionally substituted with halogen, C.sub.1-8 alkoxy or R'S(O).sub.n in which R' is C.sub.1-4 alkyl, C.sub.2-4 alkenyl or C.sub.2-4 alkynyl and n is 0, 1 or 2), cyclopropyl (optionally substituted with halogen or C.sub.1-4 alkyl), C.sub.2-8 alkenyl, C.sub.2-8 alkynyl, C.sub.1-8 alkoxy, mono- or di(C.sub.1-4)alkyl- amino or the group, R"ON.dbd.C(CN) in which R" is C.sub.Type: GrantFiled: February 2, 1990Date of Patent: March 12, 1991Assignee: Imperial Chemical Industries PLCInventors: Patrick J. Crowley, Alasdair T. Glen, Rosamund A. Spence
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Patent number: 4751240Abstract: A phenol derivative of the formulaNU--A--X--R.sup.1wherein NU is a defined phenolic nucleus including a phenyl-hydroxynaphthyl; hydroxyphenyl-naphthyl; phenyl-hydroxyindanyl, phenyl-hydroxybenzothienyl or mono-hydroxyphenyl-ethylene or vinylene nucleus; wherein A is alkylene, alkenylene or alkynylene which may be interrupted by phenylene or other linkages, wherein R.sup.1 is hydrogen, or alkyl, alkenyl, alkynyl, cycloalkyl, halogenoalkyl, alkoxyalkyl, halogenoalkoxyalkyl, aryl or arylalkyl, or R.sup.1 is joined to R.sup.2, and wherein X is --CONR.sup.2 --, --CSNR.sup.2 --, --NR.sup.12 CO--, --NR.sup.12 CS--, --NR.sup.12 CONR.sup.2 --, ##STR1## --SO.sub.2 NR.sup.2 --or --CO--, or, when R.sup.1 is not hydrogen, is --NR.sup.12 COO--, --(PO)R.sup.2 13 , --S--, --SO--or --SO.sub.2 --, wherein R.sup.2 is hydrogen or alkyl, or R.sup.1 and R.sup.2 together form alkylene; wherein R.sup.12 is hydrogen or alkyl, and wherein R.sup.22 is hydrogen, cyano or nitro; or a salt thereof when appropriate.Type: GrantFiled: April 24, 1985Date of Patent: June 14, 1988Assignee: Imperial Chemical Industries PLCInventors: Jean Bowler, Graham C. Crawley, Philip N. Edwards, Alasdair T. Glen, Michael S. Large, Brian S. Tait
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Patent number: 4386080Abstract: Novel 3,4-disubstituted-N-acylanilines of the formula: ##STR1## wherein R.sup.1, R.sup.2 and ring A are defined in claim 1; wherein R.sup.3 is hydrogen or alkyl of up to 4 carbon atoms, or is joined to R.sup.5 as stated below;wherein R.sup.4 is alkyl of 2 to 4 carbon atoms, or has the formula --CX.sup.1 X.sup.2 X.sup.3 wherein X.sup.1, X.sup.2 and X.sup.3, which may be the same or different, each is hydrogen, fluorine or chlorine; wherein R.sup.5 is hydrogen, hydroxy or alkoxy or acyloxy each of up to 15 carbon atoms, or is joined to R.sup.3 to form an oxycarbonyl group such that together with the ##STR2## part of the molecule it forms an oxazolidinedione group; and wherein R.sup.6 is hydrogen or halogen. These compounds possess antiandrogenic activity and are useful for the treatment of androgen dependent or prostatic diseases. Representative of the compounds is 3,4-dichloro-N-(2-hydroxy-2-p-nitrophenylpropionyl)aniline.Type: GrantFiled: May 21, 1981Date of Patent: May 31, 1983Assignee: Imperial Chemical Industries LimitedInventors: Neville S. Crossley, Alasdair T. Glen, Leslie R. Hughes
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Patent number: 4282218Abstract: The disclosure relates to novel 3,4-disubstituted-branched-chain-acylanilides, processes for their manufacture and pharmaceutical compositions containing them. The compounds possess anti-androgenic activity. Representative of the compounds disclosed is 3,4-dicyanoisobutyranilide.Type: GrantFiled: June 27, 1980Date of Patent: August 4, 1981Assignee: Imperial Chemical Industries LimitedInventors: Alasdair T. Glen, Richard W. Bayles
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Patent number: 4239776Abstract: The disclosure relates to novel 3,4-disubstituted-branched-chain-acylanilides, processes for their manufacture and pharmaceutical compositions containing them. The compounds possess anti-androgenic activity. Representative of the compounds disclosed is 3,4-dicyanoisobutyranilide.Type: GrantFiled: October 10, 1978Date of Patent: December 16, 1980Assignee: Imperial Chemical Industries LimitedInventors: Alasdair T. Glen, Richard W. Bayles
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Patent number: 4191775Abstract: The disclosure relates to novel 3,4-disubstituted-branched-chain-fluorinated-acylanilides, processes for their manufacture and pharmaceutical compositions containing them. The compounds possess antiandrogenic activity. Representative of the compounds disclosed is 4-nitro-3-trifluoromethyl-(2-hydroxy-2-trifluoromethylpropionyl)anilide.Type: GrantFiled: November 29, 1978Date of Patent: March 4, 1980Assignee: Imperial Chemical Industries LimitedInventor: Alasdair T. Glen