Patents by Inventor Albert HENDRIKS
Albert HENDRIKS has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20120180580Abstract: Disclosed is a disposable cartridge (10) for insertion into a sample analyzer (50), the disposable cartridge comprising a housing (16) including a sample analysis unit (18) for engaging with the sample analyzer and a sample extraction unit (14) for extracting a sample from a sample collection unit (12) and transferring said sample to the sample analysis unit, the sample extraction unit being coupled to the sample analysis unit by a flexible connection (30), wherein one of the sample analysis unit and the sample extraction unit is flexibly connected to the housing. A sample analyzer (50) for receiving such a disposable cartridge (10) is also disclosed.Type: ApplicationFiled: September 9, 2010Publication date: July 19, 2012Applicant: KONINKLIJKE PHILIPS ELECTRONICS N.V.Inventors: Albert Hendrik Jan Immink, Maurice Hubertus Elisabeth Van Der Beek
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Publication number: 20120179443Abstract: A method for enhanced oil recovery, comprising selecting a target reservoir comprising hydrocarbons; inputting a plurality of parameters concerning the reservoir and the hydrocarbons into a simulator; and modeling an enhanced oil recovery technique with the simulator using dynamic local grid refinement to provide additional model resolution of a front between an enhanced oil recovery injectant and the hydrocarbons.Type: ApplicationFiled: December 14, 2011Publication date: July 12, 2012Applicant: SHELL OIL COMPANYInventors: Diederik W. VAN BATENBURG, Paulus Maria BOERRIGTER, Jeroen Cornelis VINK, Albert Hendrik DE ZWART, Marco BOSCH
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Publication number: 20120107961Abstract: A sensor device (1) for detecting the presence of a target molecule (20) in a sample, is disclosed. The sensor device comprises a measurement sensor (2) comprising a first moiety (16) for forming a binding couple with a first further moiety comprising the target molecule (20) and a detectable label (40) and a reference sensor (3) comprising a second moiety (50) for forming a further binding couple with a second further moiety comprising a further detectable label (40?).Type: ApplicationFiled: June 24, 2010Publication date: May 3, 2012Applicant: KONINKLIJKE PHILIPS ELECTRONICS N.V.Inventors: Wendy Uyen Dittmer, Femke Karina De Theije, Albert Hendrik Jan Immink, Jeroen Hans Nieuwenhuis, Petrus Johannes Wilhelmus Van Lankvelt
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Publication number: 20110301047Abstract: The invention relates to a sensing device for sensing a fluid. The sensing device comprises an inlet port (20) for receiving the fluid (100) and a measurement chamber (25) for sensing the fluid (100). The sensing device further comprises a fluid channel (30) coupling the inlet port (20) and the measurement chamber (25) for transporting the fluid (100) from the inlet port (20) to the measurement chamber (25) and a fluid stop unit (50) for stopping and controllably releasing the flow of fluid between the inlet port (20) and the measurement chamber (25). This allows stopping the fluid before reaching the measurement chamber (25) and controllably releasing the fluid for allowing the fluid to flow into the measurement chamber (25), if the sensing device is ready for analyzing the fluid.Type: ApplicationFiled: December 7, 2009Publication date: December 8, 2011Applicant: KONINKLIJKE PHILIPS ELECTRONICS N.V.Inventors: Albert Hendrik Jan Immink, Albert F. Gootzen, Dirk Jan Nelly Vananderoye, Petrus Johannes Wilhelmu Van Lankvelt
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Publication number: 20110206575Abstract: The present invention provides a measurement device with a housing and at least one display integrated in the housing, wherein the housing comprises a recess adapted for insertion of a cartridge into the housing to deliver a sample to be measured to the device, wherein the recess has an opening at the front of the housing and a first part of the housing for insertion of the cartridge protudes in a direction enclosing an angle with a second part of the housing.Type: ApplicationFiled: November 10, 2009Publication date: August 25, 2011Applicant: KONINKLIJKE PHILIPS ELECTRONICS N.V.Inventors: Albert Hendrik Jan Immink, Petrus Johanes Wilhelmus Van Lankvelt, Tom Philippe Jean Jacques Delaey
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Publication number: 20110206560Abstract: The present invention provides a biosensor comprising a cartridge for accommodating a fluid sample, the cartridge comprising at least two chambers, wherein each chamber comprises a sensor surface with one or more binding sites. The biosensor further comprises means for generating a magnetic field at the binding sites of the sensor surfaces of the at least two chambers. The biosensor also comprises means for detecting particles accumulated at/and or proximate the binding sites of the sensor surfaces of the at least two chambers. Therein, the magnetic field at the binding sites has a sufficiently large gradient to actuate magnetic label particles towards the binding sites.Type: ApplicationFiled: October 27, 2009Publication date: August 25, 2011Applicant: KONINKLIJKE PHILIPS ELECTRONICS N.V.Inventors: Jacobus Hermanus Maria Neijzen, Reinhold Wimberger-Friedl, Joost Hubert Maas, Jeroen Hans Nieuwenhuis, Dominique Maria Bruls, Albert Hendrik Jan Immink, Mikhail M. Ovsyanko
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Publication number: 20110188030Abstract: The invention relates to a microelectronic sensor device with a light source (21) for emitting an input light beam (L1) into a transparent carrier (11) such that it is totally internally reflected at a contact surface (12) as an output light beam (L2), which is detected by a light detector (31). Frustration of the total internal reflection at the contact surface (12) can then for example be used to determine the amount of target particles (1) present at this surface. The sensor device further comprises a refractive index measurement unit (100, 200, 300) for measuring the refractive index (nB) of the sample medium, and an evaluation unit (50) for evaluating the measurement of the light detector (31) taking the measured refractive index (nB) into account and/or for changing the conditions of total internal reflection of the input light beam (L1).Type: ApplicationFiled: July 17, 2008Publication date: August 4, 2011Applicant: KONINKLIJKE PHILIPS ELECTRONICS N.V.Inventors: Coen Adrianus Verschuren, Menno Willem Jose Prins, Albert Hendrik Jan Immink
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Patent number: 7955558Abstract: A device for testing a fluid including an elongated carrier; two foam members for absorbing the fluid, which are arranged at an end of the carrier; a positioning member having a sleeve which is slidably arranged on the carrier; and a diagnostic device, which is arranged in the positioning member having a sensor die adapted to detecting at least one property of the fluid and means for supplying the fluid to a sensor surface of the sensor die. After the fluid has been supplied to the foam members, the positioning member is moved towards the end of the carrier where the foam members are located. When the diagnostic device comes into contact with one of the foam members, the fluid is squeezed from the foam member and supplied to the sensor surface of the sensor die through the fluid supplying means of the diagnostic device.Type: GrantFiled: October 30, 2006Date of Patent: June 7, 2011Assignee: Koninklijke Philips Electronics N.V.Inventors: Johannes Wilhelmus Weekamp, Menno Willem Jose Prins, Albert Hendrik Jan Immink
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Publication number: 20110093213Abstract: The invention relates to a fluid providing apparatus (5; 34) for providing a fluid to an analyzing apparatus (17; 33) for analyzing the fluid and to the analyzing apparatus (17; 33). The fluid providing apparatus (34) comprises a casing (35), which has an introduction opening (7), through which a fluid transferring element (1) is introducible into the casing (35) for transferring the fluid to the fluid providing apparatus (34). The casing (35) comprises further a fluid releasing section (8) for releasing the fluid from the fluid transferring element (1) and a fluid transferring element detection section (36) for detecting whether the fluid transferring element (1) is introduced into the casing (35) by interacting with a fluid transferring element detection unit of the analyzing apparatus (17; 33).Type: ApplicationFiled: June 22, 2009Publication date: April 21, 2011Applicant: KONINKLIJKE PHILIPS ELECTRONICS N.V.Inventors: Petrus Johannes Wilhelmus Van Lankvelt, Dominique Maria Bruls, Albert Hendrik Jan Immink
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Publication number: 20110050215Abstract: A magnetic system for biosensors or a biosystem, wherein magnetic particles that interact with molecules are brought into a magnetic field, in order to be influenced via magnetic attraction or repulsion forces. The external magnetic field is varied by mechanically moving the magnetic poles of at least one magnetic relative to the sensor or at least its surface to allow the magnetic force to be switched between effective attraction towards the sensor surface and effective repulsion away from the sensor surface.Type: ApplicationFiled: December 7, 2007Publication date: March 3, 2011Applicant: KONINKLIJKE PHILIPS ELECTRONICS N.V.Inventors: Josephus Arnoldus Henricus Maria Kahlmann, Albert Hendrik Jan Immink, Jeroen Hans Jeroen, Thea Van Der Wijk, Femke Karina De Theije
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Publication number: 20100328654Abstract: The application relates to a method and a microelectronic sensor device for making optical examinations in an investigation region (13) at the contact surface (12) of a carrier (10), wherein an input light beam (L1, L1?) is sent from a light source (20) towards the investigation region (13), and wherein an output light beam (L2, L2?) coming from the investigation region (13) is detected by a light detector (30). An evaluation unit (50) that is coupled to the light detector (30) is adapted to determine the wetting grade of the investigation region (13) based on a characteristic parameter of the output light beam (L2, L2?), e.g. its intensity. In a preferred embodiment, the evaluation unit (50) is adapted to determine a change in the light intensity caused by a liquid contacting the contact surface (12). The wetting grade may particularly be detected in a test region (14) that is located adjacent to the investigation region (13) and that has a higher roughness than the investigation region (13).Type: ApplicationFiled: June 24, 2008Publication date: December 30, 2010Applicant: KONINKLIJKE PHILIPS ELECTRONICS N.V.Inventors: Coen Adrianus Verschuren, Albert Hendrik Jan Immink
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Publication number: 20100297780Abstract: A system and method is described wherein components of the reagent (4), e.g. labelled antibodies, are separated from the biologically active sensor surface (5) by depositing the reagent (4) on a carrier surface (3) distinct from the sensor surface (5) in the detection region (2), e.g. detection chamber. In this way, a high assay reproducibility is obtained. By allowing a short, well-defined and controlled, pre-incubation time between the particles of interest, e.g. drugs, in the sample fluid (20) and the reagent (4), the reproducibility will be increased, whereas the speed of the assay is guaranteed by having all components in one detection region (2), e.g. detection chamber.Type: ApplicationFiled: July 18, 2008Publication date: November 25, 2010Applicant: Koninklijke Philips Electronics N.V.Inventors: Femke Karina De Theije, Thea Van Der Wijk, Albert Hendrik Jan Immink, Eduard Gerard Marie Pelssers, Wilhelmina Maria Hardeman, Sandra Marlin, Gordon Thomas Jowett
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Publication number: 20100289483Abstract: The present invention provides a sensor cartridge (10) for distinctively determining at least two different target moieties in a fluid sample. The sensor cartridge (10) comprises a reaction chamber (1) and at least a first and second region (2, 3) distinct from each other. The first region (2) comprises magnetic or magnetizable objects (4a) labelled with a first type of probes for specifically binding a first type of target moieties and the second region (3) comprises magnetic or magnetizable objects (4b) labelled with a second type of probes for specifically binding a second type of target moieties, the magnetic or magnetizable objects (4a, 4b) in the first and second region (2, 3) being directly contactable by the sample fluid. The present invention also provides a method for the manufacturing of such sensor devices (10) and a method for determining the presence and/or amount of at least two different target moieties in a sample fluid using such sensor cartridge (10).Type: ApplicationFiled: July 16, 2008Publication date: November 18, 2010Applicant: KONINKLIJKE PHILIPS ELECTRONICS N.V.Inventors: Albert Hendrik Jan Immink, Femke Karina De Theije, Menno Willem Jose Prins, Wendy Uyen Dittmer, Jeroen Hans Nieuwenhuis
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Publication number: 20100272608Abstract: Embodiments of the invention relates to a temperature sensor and an analytical device comprising the same. The temperature sensor comprises a carrier (11) with a detection surface (12) on which temperature indicating agents (14) are present and, optionally, at which target components can collect and optionally bind to specific capture elements. An incident light beam (L1) is transmitted into the carrier and evanescent wave excitation is induced at the detection surface (12). The amount of light in the reflected light beam (L2) or an optical, e.g. luminescence response is then detected by a light detector (31). In one example, evanescent light is affected (absorbed, scattered) by temperature indicating agents and optionally target components and/or label particles at the binding surface (12) and will therefore be missing in a frustrated total internal reflected light beam (L2).Type: ApplicationFiled: November 17, 2008Publication date: October 28, 2010Applicant: KONINKLIJKE PHILIPS ELECTRONICS N.V.Inventors: Roel Penterman, Steven Van Lierop, Albert Hendrik Jan Immink, Dirk Jan Broer
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Publication number: 20100273142Abstract: The present invention discloses microfluidic devices with a valve-like structure (3), through which magnetic particles can be transported with minimal transport of fluids. This allows sequential processing of the magnetic particles.Type: ApplicationFiled: December 16, 2008Publication date: October 28, 2010Applicant: KONINKLIJKE PHILIPS ELECTRONICS N.V.Inventors: Menno Willem Jose Prins, Joost Hubert Maas, Albert Hendrik Jan Immink, Dirkjan Bernhard Van Dam, Maatje Koets, Michel J.M. Bruyninckx, Thea Van Der Wijk, Marius losif Boamfa, Remco Den Dulk
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Publication number: 20100259254Abstract: The invention relates to a sensor device (100) and a method for the determination of the amount of target particles (1) at a contact surface (112) adjacent to a sample chamber (2). Target particles (1) in the sample chamber are detected by a sensor element (SE) and at least one corresponding sensor-signal (s, s?) is provided. An evaluation unit (EU) then determines the amount of target particles (1) in a first zone (Z1) immediately at the contracts surface (112) and a second zone (Z2) a distance (z) away from the contact surface based on this sensor-signal. In an optical measurement approach, frustrated total internal reflection taking place under different operating conditions (e.g. wavelength, angle of incidence) may be used to extract information about the first and second zones (Z1, Z2). In a magnetic measurement approach, different magnetic excitation fields may be used to excite magnetic target particles differently in the first and second zone (Z2).Type: ApplicationFiled: October 21, 2008Publication date: October 14, 2010Applicant: KONINKLIJKE PHILIPS ELECTRONICS N.V.Inventors: Coen Adrianus Johannes Verschuren, Josephus Arnoldus Henricus Maria Kahlman, Albert Hendrik Jan Immink, Mischa Megens, Jeroen Veen, Bart Michiel De Boer, Theodorus Petrus Henricus Gerardus Jansen
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Publication number: 20100253323Abstract: Detecting magnetized or magnetizable target components in a fluid containing the magnetized or magnetizable target components amongst other magnetized or magnetizable components, uses a magnetic field generator (M1, 28) to attract the magnetized or magnetizable components towards a binding surface. A magnetic field controller (C1) applies the magnetic field to concentrate the magnetized or magnetizable components in columns on the binding surface, subsequently reduces the magnetic field to enable the columns to collapse, to allow more components to reach the binding surface, and reapplies the magnetic field so as to cause other components to be pulled off the binding surface to reform columns based on the bound target components. A surface sensitive sensor (S1, 26, 29) detects the bound magnetized or magnetizable target components.Type: ApplicationFiled: December 4, 2008Publication date: October 7, 2010Applicant: KONINKLIJKE PHILIPS ELECTRONICS N.V.Inventors: Femke Karina De Theije, Dominique Maria Bruls, Thea Van Der Wijk, Coen Adrianus Verschuren, Albert Hendrik Jan Immink
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Publication number: 20100248383Abstract: A sensor cartridge has a cartridge substrate comprising an optical substrate for optical detection of a target moiety in a sample fluid based on frustrated totalinternal reflection and at least one electric structure. This way, optical read-out and electrical functions, e.g. read-out, are combined in a single substrate, in a simple and cheap manner. Also a method of fabricating such sensor cartridge is provided.Type: ApplicationFiled: November 18, 2008Publication date: September 30, 2010Applicant: KONINKLIJKE PHILIPS ELECTRONICS N.V.Inventors: Albert Hendrik Jan Immink, Marc Wilhelmus Gijsbert Ponjee, Mark Thomas Johnson, Murray Fulton Gillies
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Publication number: 20100233824Abstract: A microfluidic reactor arrangement (100) for use in detecting an analyte in a fluid sample (106) is described. The reactor arrangement is provided with a reagent providing means such that the reagent can be introduced after assembly of the reactor arrangement. The latter can be performed by introducing the reagent in the form of a solution or a dispersion and fixing it on a holding means (118) by removal of the liquid, i.e. by drying, the holding means comprising the reagent in a solid version in the detector chamber. Prior to the introduction of the reagent, components of the reactor arrangement already present, such as the sample inlet can be hydrophilised by a wetting hydrophilising technique. The invention relates to a manufacturing technique as well as to the resulting product. The invention furthermore relates to functionalizing of the reactor arrangement with a particular reagent for particular applications.Type: ApplicationFiled: July 11, 2008Publication date: September 16, 2010Applicant: KONINKLIJKE PHILIPS ELECTRONICS N.V.Inventors: Godefridus Johannes Verhoeckx, Henkrik Sibolt Van Damme, Jeroen Hans Nieuwenhuis, Sergei Shulepov, Johannes Wilhelmus Weekamp, Mara Johanna Jacoba Sijbers, Harold Johannes Antonius Brans, Femke Karina De Theije, Albert Hendrik Jan Immink
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Publication number: 20100231213Abstract: A detection system (100, 150) for qualitative or quantitative detection of a magnetic field property of a modulated magnetic field is described. The modulated magnetic field may e.g. stem from an adjacent electrical current (Iadj) or magnetic particles. The detection system (100, 150) comprises at least one magneto resistive sensor element (102), a current controller (104) for providing a sensing current (Isense) flowing through the magnetic sensor element (102) and a controlling means (108). The controlling means (108) is adapted for deriving at a first frequency f1 a temperature-related parameter of the at least one magneto resistive sensor. The controlling means (108) furthermore is adapted for deriving a qualitative or quantitative characteristic of the adjacent electrical current (Iadj) or magnetic particles, taking into account the derived temperature-related parameter. This second frequency (f1) is different from the first frequency (f1}). The invention also relates to a corresponding method.Type: ApplicationFiled: March 23, 2007Publication date: September 16, 2010Applicant: KONINKLIJKE PHILIPS ELECTRONICS N.V.Inventors: Jeroen Hans Nieuwenhuis, Theodorus Petrus Henricus Gerardus Jansen, Jeroen Veen, Josephus Arnoldus Henricus Maria Kahlman, Albert Hendrik Jan Immink