Patents by Inventor Albert J. Libchaber

Albert J. Libchaber has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Control of the expression of anchored genes using micron scale heaters
    Patent number: 6489106
    Abstract: The present invention demonstrates that gene expression can be controlled in vitro using DNA (gene) sequences immobilized on a template with micron scale temperature heaters. Such expression is controllable by varying temperature of the template on a short time scale. The present invention further demonstrates that nucleic acid constructs controlled by the present method express protein either free or bound to the nucleic acid. Based on these findings, the present invention provides methods and apparatuses useful for the preparation of in vitro programmable protein networks and protein micro arrays.
    Type: Grant
    Filed: March 10, 2000
    Date of Patent: December 3, 2002
    Assignee: NEC Research Institute, Inc.
    Inventors: G. V. Shivashankar, Shumo Liu, Albert J. Libchaber
  • Control of the expression of anchored genes using micron scale heaters
    Publication number: 20020055146
    Abstract: The present invention demonstrates that gene expression can be controlled in vitro using DNA (gene) sequences immobilized on a template with micron scale temperature heaters. Such expression is controllable by varying temperature of the template on a short time scale. The present invention further demonstrates that nucleic acid constructs controlled by the present method express protein either free or bound to the nucleic acid. Based on these findings, the present invention provides methods and apparatuses useful for the preparation of in vitro programmable protein networks and protein micro arrays.
    Type: Application
    Filed: December 7, 2001
    Publication date: May 9, 2002
    Inventors: G. V. Shivashankar, Shumo Liu, Albert J. Libchaber
  • Apparatus and method for immobilizing molecules onto a substrate
    Patent number: 6139831
    Abstract: Apparatus and method for immobilizing molecules, particularly biomolecules such as DNA, RNA, proteins, lipids, carbohydrates, or hormones onto a substrate such as glass or silica; patterns of immobilization can be made resulting in addressable, discrete arrays of molecules on a substrate, having applications in bioelectronics, DNA hybridization assays, drug assays, etc.
    Type: Grant
    Filed: May 28, 1998
    Date of Patent: October 31, 2000
    Assignee: The Rockfeller University
    Inventors: Ganaganor Visweswara Shivashankar, Albert J. Libchaber