Abstract: Preparations are provided for the treatment of irritated, pruritic and dry skin conditions by the retardation of the degenerative or chemical breakdown of the skin sebum, lipids and surface films. These objectives are accomplished by the special combination of lipids/lipoids comprising glycerol trioleate and other glyceride oils of certain fatty acid constituency and other properties, tocopherol, hydrogenated glyceride oil or fat and lecithin, more particularly in special combination with squalene or squalane, collagen protein, a humectant and isopropyl palmitate.