Patents by Inventor Albin Fredriksson
Albin Fredriksson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11969608Abstract: A method of generating a radiotherapy plan for ion therapy, wherein the beam (6) is shaped by means of passive devices is arranged to allow variation in settings of at least one of the passive devices and/or the MU during the delivery of the beam and to control the movement of the patient and/or the beam in such a way as to create an arc. The arc is preferably a continuous arc or includes at least one continuous sub-arc. The method may include forward planning or optimization. In the latter case, the optimization uses an optimization problem set up to allow variation in settings of at least one of the range modulating device (9), the aperture element (11) and the MU during the delivery of the arc. Computer programs control the planning and the delivery.Type: GrantFiled: December 12, 2019Date of Patent: April 30, 2024Assignee: RaySearch Laboratories ABInventors: Albin Fredriksson, Erik Engwall, Kjell Eriksson, Erik Traneus
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Patent number: 11865363Abstract: The present disclosure generally relates to the field of radiation treatment. More specifically, the present disclosure generally relates to methods and radiation treatment systems for facilitating a multimodal radiation therapy treatment plan, in particular a multimodal radiation therapy plan employing a combined photon beam and electron beam radiation treatment. According to one example embodiment described in the disclosure, a method may comprise obtaining information related to a set of candidate beam types for the combined photon beam and electron beam radiation treatment; comparing the set of candidate beam types against a selection criterion to establish a subset of beam types from the candidate beam types; and generating the combined photon beam and electron beam radiation treatment plan utilizing the thus established subset of beam types.Type: GrantFiled: May 27, 2019Date of Patent: January 9, 2024Assignee: RaySearch Laboratories ABInventors: Rasmus Bokrantz, Albin Fredriksson, Kjell Eriksson, Erik Engwall, Erik Traneus
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Publication number: 20230381539Abstract: A method (100) for generating a treatment plan specifying an irradiation of a patient, the method comprising: a dose inference stage (112), including using a model to infer a spatial dose from patient data; a dose mimicking stage (116), including executing a robust optimization process to generate a deliverable treatment plan which is consistent with the inferred spatial dose, wherein the robust optimization considers a plurality of scenarios relating to patient data uncertainty.Type: ApplicationFiled: November 18, 2021Publication date: November 30, 2023Inventors: Albin FREDRIKSSON, Hanna GRUSELIUS, Mats HOLMSTROM, David ANDERSSON
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Publication number: 20230302298Abstract: Generating a robust radiotherapy treatment plan for a treatment volume, defined using a plurality of voxels, of a subject. A first and at least one second image of the treatment volume are received. A distribution of mapped doses in the first image is generated by mapping a dose defined in the at least one second image to the first image using image registration. An optimization problem is defined using at least one optimization function for a total dose, related to the radiotherapy treatment. At least one optimization function value is calculated based on at least two mapped doses in the distribution of mapped doses in the first image. A radiotherapy treatment plan is generated by optimizing the at least one optimization function value evaluated by taking into account the at least two mapped doses in the distribution of mapped doses.Type: ApplicationFiled: March 20, 2023Publication date: September 28, 2023Inventors: Ivar BENGTSSON, Albin FREDRIKSSON
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Publication number: 20230211177Abstract: An inverse-planning method (100), by which a treatment plan specifying a non-photon irradiation of a patient including a target volume is generated, comprises: obtaining (110, 112) first and second plan goals in terms of a respective first and second numerical condition on the treatment plan’s photon-equivalent dose as computed using a first and second RBE factor; and generating (114) the treatment plan by an optimization process aiming to satisfy the first, second and any further plan goals, wherein (a) the first and second plan goals apply to volumes which either are included in the TV or are completely or partially separate from the TV and/or (b) the first and second RBE factors are variable. In a further aspect, a data carrier provides a treatment plan with these characteristics together with reporting quantities relating to fulfilment of the first and second plan goals.Type: ApplicationFiled: April 9, 2021Publication date: July 6, 2023Inventors: Martin JANSON, Albin FREDRIKSSON, Erik TRANEUS, Kjell ERIKSSON
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Publication number: 20230144962Abstract: A computer-based method of optimizing a radiotherapy treatment plan for a patient is proposed, wherein a complete treatment comprising both external beam therapy and brachytherapy is optimized in one procedure using an optimization problem comprising an objective function designed to optimize the total dose distribution as a combination of a first dose distribution to be provided by a first radiation set and a second dose distribution to be provided by a second radiation set. One of the radiation sets is external beam radiotherapy and the other is brachytherapy. The optimization is based on a total desired dose for the whole treatment, images of the patient before the treatment starts and an estimated image of the patient after the first radiation set has been delivered.Type: ApplicationFiled: March 22, 2021Publication date: May 11, 2023Inventors: Bjorn ANDERSSON, Erik ENGWALL, Albin FREDRIKSSON, Kjell ERIKSSON
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Publication number: 20230141197Abstract: A computer-based method of optimizing a radiotherapy treatment plan for a patient is proposed, wherein a treatment plan to be provided by one radiation set is optimized taking into account a previously delivered dose delivered by a different radiation set. One of the radiation sets is external beam radiotherapy and the other is brachytherapy.Type: ApplicationFiled: March 22, 2021Publication date: May 11, 2023Inventors: Bjorn ANDERSSON, Erik ENGWALL, Albin FREDRIKSSON, Kjell ERIKSSON
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Patent number: 11607559Abstract: It is provided a method for determining arc costs. The method comprises the steps of: determining a plurality of beam orientations; evaluating a set of at least one cost function comprising an intermediate exposure cost function that is evaluated by performing the substeps of: projecting the at least one target volumes on a beam plane; determining an alignment angle based on a collimator angle value; finding any intermediate area in the beam plane along the alignment angle between areas of the at least one target volume projection; determining a value of the intermediate exposure cost function. The method further comprises the steps of: finding a plurality of arcs, wherein each arc comprises a sequence of a plurality of beam orientations; and calculating, for each arc in the plurality of arcs, at least one arc cost based on the cost function values of the beam orientations of the arc.Type: GrantFiled: September 7, 2018Date of Patent: March 21, 2023Assignee: RaySearch Laboratories ABInventors: Kjell Eriksson, Albin Fredriksson, Henrik Olsson
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Publication number: 20220296925Abstract: A method for generating a robust radiotherapy treatment plan for a treatment volume of a subject, the treatment volume being defined using a plurality of voxels, the method comprising the steps of defining (S100) an optimization problem using at least one optimization function for a biological endpoint related to the radiotherapy treatment; defining (S102) a set of scenarios comprising at least a first scenario and a second scenario, wherein at least two of the scenarios in the set of scenarios represent different biological models to quantify the same biological endpoint; calculating (S104) an optimization function value for each scenario in the set of scenarios; generating (S106) a radiotherapy treatment plan by robustly optimizing the optimization function value evaluated over the set of scenariosType: ApplicationFiled: June 2, 2020Publication date: September 22, 2022Applicant: RaySearch Laboratories ABInventors: Minna WEDENBERG, Jakob ÖDÉN, Albin FREDRIKSSON, Erik TRANEUS
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Patent number: 11413474Abstract: A method is proposed for evaluating the robustness of a radiotherapy treatment plan. The method comprises, defining a number of scenarios, each comprising one or more errors for each fraction of the plan, including interfractional and/or intrafractional errors, and calculating a dose distribution resulting from the scenario; The robustness of the plan is then evaluated based at least one of the following i. the probability of fulfilling a set of clinical goals estimated as the clinical goal fulfilment over the scenarios ii. the range of DVH values over the scenarios iii. dose statistics for dose distributions defined as voxel-wise aggregates over the scenario doses.Type: GrantFiled: April 3, 2018Date of Patent: August 16, 2022Assignee: RaySearch Laboratories ABInventor: Albin Fredriksson
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Patent number: 11389669Abstract: A method of radiotherapy treatment planning for creating a plan for delivery of radiation to a patient in at least one particle-based arc is proposed. The delivery time for the plan is reduced by including a penalty in the objective function, designed to limit the number of energy layers and/or the number of energy layer changes.Type: GrantFiled: April 1, 2019Date of Patent: July 19, 2022Assignee: RaySearch Laboratories ABInventors: Erik Traneus, Kjell Eriksson, Erik Engwall, Rasmus Bokrantz, Albin Fredriksson
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Publication number: 20220072334Abstract: A method of optimizing the use of resources in treatment planning involving more than one radiation set delivered to one or more patients, the radiation sets requiring different resources, respectively, wherein the optimization is performed using an optimization problem comprising an optimization function related to the first and second sets of resources. The method may be used for optimizing one plan for one patient, or a number of plans for different patients, in such a way that the available resources are used in the best possible way.Type: ApplicationFiled: December 12, 2019Publication date: March 10, 2022Applicant: RaySearch Laboratories ABInventors: Albin FREDRIKSSON, Rasmus BOKRANTZ, Erik ENGWALL, Kjell ERIKSSON, Lars GLIMELIUS
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Publication number: 20220040500Abstract: A method of generating a radiotherapy plan for ion therapy, wherein the beam (6) is shaped by means of passive devices is arranged to allow variation in settings of at least one of the passive devices and/or the MU during the delivery of the beam and to control the movement of the patient and/or the beam in such a way as to create an arc. The arc is preferably a continuous arc or includes at least one continuous sub-arc. The method may include forward planning or optimization. In the latter case, the optimization uses an optimization problem set up to allow variation in settings of at least one of the range modulating device (9), the aperture element (11) and the MU during the delivery of the arc. Computer programs control the planning and the delivery.Type: ApplicationFiled: December 12, 2019Publication date: February 10, 2022Applicant: RaySearch Laboratories ABInventors: Albin FREDRIKSSON, Erik ENGWALL, Kjell ERIKSSON, Erik TRANEUS
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Publication number: 20220023664Abstract: An ion-based radiotherapy plan for passive delivery of one or more beams (7) uses an optimization problem set up to allow variation in settings of the range modulating device, and/or settings of the aperture element during the delivery of the first beam, so that said plan will include modulation of the fluence of the beam during the delivery of the beam. The optimization problem is set up to allow variation of the settings of an aperture element (11), a range modulating device (9) during delivery of each beam, so that said plan will include modulation in depth of the beam during the delivery of the beam.Type: ApplicationFiled: December 19, 2019Publication date: January 27, 2022Inventors: Albin FREDRIKSSON, Erik ENGWALL
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Patent number: 11224762Abstract: A method of radiotherapy treatment planning comprises optimizing a treatment plan based on at least one proposed dose map according to a set of clinical goals The resulting dose distribution is compared to the at least one clinical goal, and if the optimized dose distribution does not fulfil the at least one clinical goal, continuing with step d the dose map is adjusted before a new treatment plan is optimized. When the optimized dose distribution fulfils the clinical goals, the treatment plan is accepted.Type: GrantFiled: April 4, 2018Date of Patent: January 18, 2022Assignee: RaySearch Laboratories ABInventor: Albin Fredriksson
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Publication number: 20210205635Abstract: The present disclosure generally relates to the field of radiation treatment. More specifically, the present disclosure generally relates to methods and radiation treatment systems for facilitating a multimodal radiation therapy treatment plan, in particular a multimodal radiation therapy plan employing a combined photon beam and electron beam radiation treatment. According to one example embodiment described in the disclosure, a method may comprise obtaining information related to a set of candidate beam types for the combined photon beam and electron beam radiation treatment; comparing the set of candidate beam types against a selection criterion to establish a subset of beam types from the candidate beam types; and generating the combined photon beam and electron beam radiation treatment plan utilizing the thus established subset of beam types.Type: ApplicationFiled: May 27, 2019Publication date: July 8, 2021Applicant: RaySearch Laboratories ABInventors: Rasmus BOKRANTZ, Albin FREDRIKSSON, Kjell ERIKSSON, Erik ENGWALL, Erik TRANEUS
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Publication number: 20210201546Abstract: In accordance with one or more embodiments herein, a system for generating an optimized parametrized conversion function T for converting an original medical image of a first image type into a converted medical image of a second image type is provided.Type: ApplicationFiled: May 20, 2019Publication date: July 1, 2021Applicant: RaySearch Laboratories ABInventors: Sebastian ANDERSSON, Albin FREDRIKSSON, Marcus NORDSTRÖM, Rasmus NILSSON
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Patent number: 11027148Abstract: A system plans a radiation therapy treatment of a target volume based on inputs in the form of: a set of candidate beams (B), where each beam defines an arrangement of a therapeutic beam relative to the target volume; a treatment plan (x) for the radiation therapy treatment that uses a subset of the candidate beams (B); an objective function (F) describing a quality of the treatment plan (x); and a feasible region (X) describing requirements on the treatment plan (x) that must be fulfilled. The objective function (F) and/or the feasible region (X) also reflect a first complexity criterion (?(x)?{circumflex over (?)}) limiting a first complexity measure (?(x)) to be less than or equal to a maximum first complexity ({circumflex over (?)}). An optimization step is executed repeatedly; whereby, in each iteration, an updated treatment plan (x?) is calculated by optimizing the treatment plan (x) with respect to the objective function (F) and the feasible region (X).Type: GrantFiled: January 27, 2017Date of Patent: June 8, 2021Assignee: RaySearch Laboratories ABInventors: Rasmus Bokrantz, Albin Fredriksson
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Patent number: 10974068Abstract: A scenario-based treatment plan optimization method for radiotherapy treatment is proposed, in which a first and a second possible scenario are defined. Different optimization functions are defined for the scenarios and the treatment plan is optimized applying the first optimization function under the first scenario and the second optimization function under the second scenario, thereby obtaining a first optimized radiotherapy treatment plan.Type: GrantFiled: April 5, 2017Date of Patent: April 13, 2021Assignee: RaySearch Laboratories ABInventors: Rasmus Bokrantz, Albin Fredriksson
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Publication number: 20210101021Abstract: A method of radiotherapy treatment planning comprises optimizing a treatment plan based on at least one proposed dose map according to a set of clinical goals The resulting dose distribution is compared to the at least one clinical goal, and if the optimized dose distribution does not fulfil the at least one clinical goal, continuing with step d the dose map is adjusted before a new treatment plan is optimized. When the optimized dose distribution fulfils the clinical goals, the treatment plan is accepted.Type: ApplicationFiled: April 4, 2018Publication date: April 8, 2021Applicant: RaySearch Laboratories ABInventor: Albin FREDRIKSSON