Patents by Inventor Albrecht W. Frauendorf

Albrecht W. Frauendorf has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method and composition for chemical synthesis on an open environment support surface using high boiling point organic solvents to control evaporation
    Patent number: 6337393
    Abstract: A method for reducing evaporation of a liquid reagent solution during solid phase, micro-scale chemical synthesis of a molecule comprising sub-units on an open environment solid support surface. The method includes the steps of providing an open solid support surface including at least one binding site which is functionalized with a reactive chemical moiety; and depositing a substantially controlled and minute volume of liquid reagent solution onto the support surface, and in contact with the binding site. The reagent solution includes reactants contained in at least one relatively high boiling point solvent, in contrast to standard organic solvents for such reagents. Application of a high boiling point solvent substantially reduces evaporation of the reagent solution in the open environment during synthesis on the solid support while enabling the maintenance of a substantially high reaction yield.
    Type: Grant
    Filed: September 14, 2000
    Date of Patent: January 8, 2002
    Assignee: Protogene Laboratories, Inc.
    Inventors: Thomas M. Brennan, Albrecht W. Frauendorf
  • Method and composition for chemical synthesis using high boiling point organic solvents to control evaporation
    Patent number: 6177558
    Abstract: A method for reducing evaporation of a liquid reagent solution during solid phase, micro-scale chemical synthesis of a molecule comprising sub-units on an open environment solid support surface. The method includes the steps of providing an open solid support surface including at least one binding site which is functionalized with a reactive chemical moiety; and depositing a substantially controlled and minute volume of liquid reagent solution onto the support surface, and in contact with the binding site. The reagent solution includes reactants contained in at least one relatively high boiling point solvent, in contrast to standard organic solvents for such reagents. Application of a high boiling point solvent substantially reduces evaporation of the reagent solution in the open environment during synthesis on the solid support while enabling the maintenance of a substantially high reaction yield.
    Type: Grant
    Filed: November 13, 1997
    Date of Patent: January 23, 2001
    Assignee: Protogene Laboratories, Inc.
    Inventors: Thomas M. Brennan, Albrecht W. Frauendorf