Patents by Inventor Ale Narvanen

Ale Narvanen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20090214427
    Abstract: Isolated peptides comprising an amino acid sequence having Formula I X1X2X3X4,??I wherein X1 is an optional residue of an amino acid selected from the group of R, F, Y, S and conservative substitutes thereof; X2 stands for a residue of an amino acid selected from the group of R and A and conservative substitutes thereof; X3 is a residue of an amino acid selected from the group of F, P, G, Q, M and conservative substitutes thereof; and X4 is a residue of an amino acid selected from the group of K, F, G, P and conservative substitutes thereof. The novel peptides are capable of binding to human kallikrein 2 and of inhibiting the proteolytic activity of human kallikrein 2. They can be used in prostate cancer treatment as such or in combination with other ligands modulating the activity of factors mediating tumor growth.
    Type: Application
    Filed: September 5, 2005
    Publication date: August 27, 2009
    Applicant: Licentia OY
    Inventors: Ulf-Hakan Stenman, Jari Leinonen, Ale Narvanen
  • Publication number: 20080312141
    Abstract: The present invention relates to novel peptide ligands for prostate specific antigen (PSA) binding specifically with it and enhancing its enzyme activity, to a process for preparation of these peptides, to diagnostic and pharmaceutical compositions comprising these peptides, to the use of these peptides for pharmaceutical and research preparations, to methods using these peptides in diagnostic assays for determination of the concentrations of various molecular forms of PSA, to methods for modulating the PSA enzyme activity and PSA activity dependent conditions by using these peptides either in vivo or in vitro and to the use of these peptides in procedures for biochemical isolation and purification of PSA.
    Type: Application
    Filed: March 7, 2008
    Publication date: December 18, 2008
    Inventors: Ulf-Hakan STENMAN, Erkki Koivunen, Jari Leinonen, Ale Narvanen
  • Patent number: 7414023
    Abstract: The present invention relates to novel peptide ligands for prostate specific antigen (PSA) binding specifically with it and enhancing its enzyme activity, to a process for preparation of these peptides, to diagnostic and pharmaceutical compositions comprising these peptides, to the use of these peptides for pharmaceutical and research preparations, to methods using these peptides in diagnostic assays for determination of the concentrations of various molecular forms of PSA, to methods for modulating the PSA enzyme activity and PSA activity dependent conditions by using these peptides either in vivo or in vitro and to the use of these peptides in procedures for biochemical isolation and purification of PSA.
    Type: Grant
    Filed: October 1, 2001
    Date of Patent: August 19, 2008
    Assignee: Licentia Ltd.
    Inventors: Stenman Ulf-Hakan, Erkki Koivunen, Jari Leinonen, Ale Närvänen
  • Publication number: 20040106557
    Abstract: The present invention relates to novel peptide ligands for prostate specific antigen (PSA) binding specifically with it and enhancing its enzyme activity, to a process for preparation of these peptides, to diagnostic and pharmaceutical compositions comprising these peptides, to the use of these peptides for pharmaceutical and research preparations, to methods using these peptides in diagnostic assays for determination of the concentrations of various molecular forms of PSA, to methods for modulating the PSA enzyme activity and PSA activity dependent conditions by using these peptides either in vivo or in vitro and to the use of these peptides in procedures for biochemical isolation and purification of PSA.
    Type: Application
    Filed: September 26, 2003
    Publication date: June 3, 2004
    Inventors: Stenman Ulf-Hakan, Erkki Koivunen, Jari Leinonen, Ale Narvanen
  • Patent number: 5160378
    Abstract: The invention concerns a washing device for treatment of rods attached to a plate with a solution. According to the invention the rods (6) are placed in ducts (4) through which the solution is passed. The invention can be used in particular in peptide syntheses and in immunological assay methods.
    Type: Grant
    Filed: September 21, 1990
    Date of Patent: November 3, 1992
    Assignee: Labsystems Oy
    Inventors: Jukka Tuunanen, Ale Narvanen, Mario Geysen