Patents by Inventor Aleck Hercbergs

Aleck Hercbergs has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • BIMODAL MODIFIED RELEASE COMPOSITIONS FOR CANCER TREATMENT
    Publication number: 20200222348
    Abstract: The present invention discloses bimodal modified release fixed-dose combination (FDC) compositions and therapeutic methods for treatment of cancer by administration to a patient in need thereof of a FDC composition comprising a first active agent which is triiodothyronine (T3) or a T3 functional analog formulated to be delivered in the pulsatile delivery mode. and a second active agent which is at least one anti-thyroid agent, formulated to be delivered in immediate release (IR) mode, sustained release (SR) mode or combined immediate/slow release (IR/SR) mode.
    Type: Application
    Filed: May 1, 2017
    Publication date: July 16, 2020
    Inventors: Osnat ASHUR-FABIAN, Aleck HERCBERGS, Yoram SELA
  • Methods, compositions and kits for providing a therapeutic treatment
    Patent number: 10398789
    Abstract: The present invention encompasses a therapeutic method which employs treatment of a disease such as cancer with triiodothyronine (T3) together with an anti-thyroid treatment such as treatment with an anti-thyroid agent, treatment with radioiodine and surgical removal of all or part of the thyroid gland. A pharmaceutical composition comprising T3 and an anti-thyroid agent and a kit comprising the same are also encompassed by the invention.
    Type: Grant
    Filed: April 11, 2017
    Date of Patent: September 3, 2019
    Inventors: Osnat Ashur-Fabian, Aleck Hercbergs
  • METHODS, COMPOSITIONS AND KITS FOR PROVIDING A THERAPEUTIC TREATMENT
    Publication number: 20170274104
    Abstract: The present invention encompasses a therapeutic method which employs treatment of a disease such as cancer with triiodothyronine (T3) together with an anti-thyroid treatment such as treatment with an anti-thyroid agent, treatment with radioiodine and surgical removal of all or part of the thyroid gland. A pharmaceutical composition comprising T3 and an anti-thyroid agent and a kit comprising the same are also encompassed by the invention.
    Type: Application
    Filed: April 11, 2017
    Publication date: September 28, 2017
    Inventors: Osnat ASHUR-FABIAN, Aleck HERCBERGS
  • Methods, compositions and kits for providing a therapeutic treatment
    Patent number: 9655984
    Abstract: The present invention encompasses a therapeutic method which employs treatment of a disease such as cancer with triiodothyronine (T3) together with an anti-thyroid treatment such as treatment with an anti-thyroid agent, treatment with radioiodine and surgical removal of all or part of the thyroid gland. A pharmaceutical composition comprising T3 and an anti-thyroid agent and a kit comprising the same are also encompassed by the invention.
    Type: Grant
    Filed: April 28, 2011
    Date of Patent: May 23, 2017
    Inventors: Osnat Ashur-Fabian, Aleck Hercbergs
  • Nanoparticle and polymer formulations for thyroid hormone analogs, antagonists, and formulations and uses thereof
    Patent number: 9220788
    Abstract: Disclosed are methods of treating subjects having conditions related to angiogenesis including administering an effective amount of a polymeric nanoparticle form of thyroid hormone agonist, partial agonist or an antagonist thereof, to promote or inhibit angiogenesis in the subject. Nanoparticle forms of thyroid hormone or thyroid hormone analogs as well as uses thereof are also disclosed.
    Type: Grant
    Filed: June 15, 2010
    Date of Patent: December 29, 2015
    Assignee: NANOPHARMACEUTICALS LLC
    Inventors: Paul J. Davis, Faith B. Davis, Shaker A. Mousa, Gennadi V. Glinksy, Aleck Hercbergs
  • METHODS, COMPOSITIONS AND KITS FOR PROVIDING A THERAPEUTIC TREATMENT
    Publication number: 20130129615
    Abstract: The present invention encompasses a therapeutic method which employs treatment of a disease such as cancer with triiodothyronine (T3) together with an anti-thyroid treatment such as treatment with an anti-thyroid agent, treatment with radioiodine and surgical removal of all or part of the thyroid gland. A pharmaceutical composition comprising T3 and an anti-thyroid agent and a kit comprising the same are also encompassed by the invention.
    Type: Application
    Filed: April 28, 2011
    Publication date: May 23, 2013
    Inventors: Osnat Ashur-Fabian, Aleck Hercbergs
  • NANOPARTICLE AND POLYMER FORMULATIONS FOR THYROID HORMONE ANALOGS, ANTAGONISTS, AND FORMULATIONS AND USES THEREOF
    Publication number: 20110052715
    Abstract: Disclosed are methods of treating subjects having conditions related to angiogenesis including administering an effective amount of a polymeric nanoparticle form of thyroid hormone agonist, partial agonist or an antagonist thereof, to promote or inhibit angiogenesis in the subject. Nanoparticle forms of thyroid hormone or thyroid hormone analogs as well as uses thereof are also disclosed.
    Type: Application
    Filed: June 15, 2010
    Publication date: March 3, 2011
    Inventors: Paul J. Davis, Faith B. Davis, Shaker A. Mousa, Gennadi V. Glinsky, Aleck Hercbergs
  • Nanoparticle and polymer formulations for thyroid hormone analogs, antagonists and formulations and uses thereof
    Publication number: 20090022806
    Abstract: Disclosed are methods of treating subjects having conditions related to angiogenesis including administering an effective amount of a polymeric Nanoparticle form of thyroid hormone agonist, partial agonist or an antagonist thereof, to promote or inhibit angiogenesis in the subject. Compositions of the polymeric forms of thyroid hormone, or thyroid hormone analogs, are also disclosed.
    Type: Application
    Filed: December 21, 2007
    Publication date: January 22, 2009
    Inventors: Shaker A. Mousa, Paul J. Davis, Aleck Hercbergs