Patents by Inventor Alejandro Flores
Alejandro Flores has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230142150Abstract: Conventionally, users of integration platforms, or other platforms that utilize many different services, must install, manage, configure, and administer the underlying resources for connectivity with the platforms. Adapter orchestration as a service (AOaaS) simplifies this process by enabling users to quickly and easily deploy an adapter orchestration service comprising instances of selected adapters for multiple services in discrete, autonomous containers that can be spun up and down as needed. The adapters may translate data for all of the services to a common format. Clients may access the data for all of the adapters in the adapter orchestration service via a single application programming interface (API) of the adapter orchestration service, which provides access to the data in the common format.Type: ApplicationFiled: November 9, 2022Publication date: May 11, 2023Inventors: Alejandro Flores, Madhav Srimadh Bhagavatam, Ed Macosky, Rajesh Raheja, Dana Burkart
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Patent number: 11574353Abstract: Examples disclosed herein are relevant to systems, methods, and other technology for determining furniture compatibility. For example, graph neural networks (GNNs) that leverage relational information between furniture items in a set may be used as models to predict a compatibility score indicative of visual compatibility of furniture items across the set. In one implementation, the GNN-based model can extend the concept of a siamese network to multiple inputs and branches and use a generalized contrastive loss function. In another implementation, the GNN-based model learns both an edge function and the function that generates the compatibility score. The predicted compatibility score can be used for a variety of purposes, including furniture item recommendations.Type: GrantFiled: April 24, 2020Date of Patent: February 7, 2023Assignee: Target Brands, Inc.Inventors: Luisa Fernanda Polanía Cabrera, Mauricio Alejandro Flores Ríos, Matthew Seth Nokleby, Yiran Li
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Patent number: 11571457Abstract: The invention relates to the field of minimal residual disease (MRD) diagnostics, which is progressively more applied for the evaluation of treatment effectiveness in patients with a hematological malignancy, such as B-cell precursor acute lymphoblastic leukemia (BCP-ALL), B-cell chronic lymphocytic leukemia (B-CLL), and multiple myeloma (MM). Provided are unique reagent compositions with carefully selected and thoroughly tested combinations of antibodies, for ?8-color flow cytometric stainings as well as for 10-color and 12-color flow cyometric stainings, which can reach sensitivities of at least 10?4, even down to 10?5. Also provided are diagnostic kits and methods for detecting MRD.Type: GrantFiled: October 30, 2020Date of Patent: February 7, 2023Assignee: Erasmus University Medical Center RotterdamInventors: Jacobus Johannes Maria van Dongen, José Alberto Orfao de Matos Correia e Vale, Juan Alejandro Flores Montero, Julia Maria Almeida Parra, Vincent Henricus Johannes Van der Velden, Sebastian Böttcher, Anthonie Willem Langerak, Ester Mejst{hacek over (r)}íková, Tomasz Szczepański, Matthias Ritgen, Paulo Jorge Monteiro Da Silva Lucio
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Publication number: 20220140753Abstract: A power and/or electricity generating source and/or component that is TENG-based, and that may be configured as an assembly and/or component for powering one or more electronic devices, is disclosed, A case, carrier or other carrying container, for example a case for a cell phone, ipad, electronic tablet, personal computer, or any similar device, that provides an electricity source to power the cell phone, ipad, electronic tablet, is disclosed. The energy generating carriers and/or containers and configurations thereof, also provide an electricity energy storage source. This electronic energy storage source may be incorporated within an electronic device itself, or may be incorporated within the case and/or covering. Upon walking or touching a surface of an electronic device, the power generating source will harness mechanical energy, and provide for the generation of electricity with the one or more TENG components (TESTEC) that comprise the energy generating unit. Metal particles (silver, copper, etc.Type: ApplicationFiled: November 5, 2021Publication date: May 5, 2022Inventors: Mohammed Jasim Uddin, Abu Musa Abdullah, Alejandro Flores
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Publication number: 20210263017Abstract: The invention relates to the field of flow cytometry and more particularly to a panel of antibody reagents conjugated to fluorescent compounds. Provided are reagent compositions, comprising at least eight distinct fluorochrome-conjugated antibodies comprising a set of at least there identification antibodies for the identification of a leukocyte population of interest and at least four characterization antibodies for further characterization and/or classification of said leukocyte population. Also provided are kits and methods related to the reagent compositions.Type: ApplicationFiled: March 8, 2021Publication date: August 26, 2021Inventors: Jacobus Johannes Maria van Dongen, José Alberto Orfao de Matos Correia e Vale, Juan Alejandro Flores-Montero, Julia Maria Almeida Parra, Vincent Henricus Johannes van der Velden, Sebastian Böttcher, Andrew Craig Rawstron, Ruth Mary de Tute, Ludovic Bernard Simon Lhermitte, Vahid Asnafi, Ester Mejstríková, Tomasz Szczepanski, Paulo Jorge Monteiro Da Silva Lucio, Marta Martín Ayuso, Carlos Eduardo Pedreira
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Publication number: 20210177936Abstract: The invention relates to the field of minimal residual disease (MRD) diagnostics, which is progressively more applied for the evaluation of treatment effectiveness in patients with a hematological malignancy, such as B-cell precursor acute lymphoblastic leukemia (BCP-ALL), B-cell chronic lymphocytic leukemia (B-CLL), and multiple myeloma (MM). Provided are unique reagent compositions with carefully selected and thoroughly tested combinations of antibodies, for ?8-color flow cytometric stainings as well as for 10-color and 12-color flow cyometric stainings, which can reach sensitivities of at least 10?4, even down to 10?5. Also provided are diagnostic kits and methods for detecting MRD.Type: ApplicationFiled: October 30, 2020Publication date: June 17, 2021Inventors: Jacobus Johannes Maria van Dongen, José Alberto Orfao de Matos Correia e Vale, Juan Alejandro Flores Montero, Julia Maria Almeida Parra, Vincent Henricus Johannes Van der Velden, Sebastian Böttcher, Anthonie Willem Langerak, Ester Mejstríková, Tomasz Szczepanski, Matthias Ritgen, Paulo Jorge Monteiro Da Silva Lucio
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Patent number: 11015143Abstract: Disclosed are fragrance-enhanced cleaning compositions including a mixture of a linear alkyLbenzene sulfonate (LAS) and a sodium lauryl ether sulfate (SLES), wherein the mixture is present in the cleaning composition in an amount of about 1%-2% by weight and wherein a weight ratio of LAS:SLES is about 3:1 to about 1:1 or about 6:1 to about 4:1; and a fragrance. Methods of preparing and using the present cleaning compositions are also disclosed. In addition, methods of formulating a cleaning composition having an enhanced fragrance performance are provided.Type: GrantFiled: July 10, 2015Date of Patent: May 25, 2021Assignee: Colgate-Palmolive CompanyInventors: Jorge Antonio Maldonado Ortega, Edna Ambundo, Jose Alejandro Flores Sanabria, Antonia de la Cruz Ramirez Mendez, Maria Eugenia Rojo Dieguez, Luis Javier Rivera Cruz
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Publication number: 20210110457Abstract: Examples disclosed herein are relevant to systems, methods, and other technology for determining furniture compatibility. For example, graph neural networks (GNNs) that leverage relational information between furniture items in a set may be used as models to predict a compatibility score indicative of visual compatibility of furniture items across the set. In one implementation, the GNN-based model can extend the concept of a siamese network to multiple inputs and branches and use a generalized contrastive loss function. In another implementation, the GNN-based model learns both an edge function and the function that generates the compatibility score. The predicted compatibility score can be used for a variety of purposes, including furniture item recommendations.Type: ApplicationFiled: April 24, 2020Publication date: April 15, 2021Inventors: Luisa Fernanda POLANÍA CABRERA, Mauricio Alejandro FLORES RÍOS, Matthew Seth NOKLEBY, Yiran LI
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Patent number: 10942171Abstract: The invention relates to the field of flow cytometry and more particularly to a panel of antibody reagents conjugated to fluorescent compounds. Provided are reagent compositions, comprising at least eight distinct fluorochrome-conjugated antibodies comprising a set of at least there identification antibodies for the identification of a leukocyte population of interest and at least four characterization antibodies for further characterization and/or classification of said leukocyte population. Also provided are kits and methods related to the reagent compositions.Type: GrantFiled: December 20, 2017Date of Patent: March 9, 2021Assignee: Erasmus University Medical Center RotterdamInventors: Jacobus Johannes Maria van Dongen, Jose Alberto Orfao de Matos Correia e Vale, Juan Alejandro Flores-Montero, Julia Maria Almeida Parra, Vincent Henricus Johannes van der Velden, Sebastian Böttcher, Andrew Craig Rawstron, Ruth Mary de Tute, Ludovic Bernard Simon Lhermitte, Vahid Asnafi, Ester Mejstrikova, Tomasz Szczepanski, Paulo Jorge Monteiro Da Silva Lucio, Marta Martín Ayuso, Carlos Eduardo Pedreira
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Patent number: 10942172Abstract: The invention relates to the field of flow cytometry and more particularly to a panel of antibody reagents conjugated to fluorescent compounds. Provided are reagent compositions, comprising at least eight distinct fluorochrome-conjugated antibodies comprising a set of at least there identification antibodies for the identification of a leukocyte population of interest and at least four characterization antibodies for further characterization and/or classification of said leukocyte population. Also provided are kits and methods related to the reagent compositions.Type: GrantFiled: December 20, 2017Date of Patent: March 9, 2021Assignee: Erasmus University Medical Center RotterdamInventors: Jacobus Johannes Maria van Dongen, Jose Alberto Orfao de Matos Correia e Vale, Juan Alejandro Flores-Montero, Julia Maria Almeida Parra, Vincent Henricus Johannes van der Velden, Sebastian Böttcher, Andrew Craig Rawstron, Ruth Mary de Tute, Ludovic Bernard Simon Lhermitte, Vahid Asnafi, Ester Mejstrikova, Tomasz Szczepanski, Paulo Jorge Monteiro Da Silva Lucio, Marta Martin Ayuso, Carlos Eduardo Pedreira
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Patent number: 10874710Abstract: The invention relates to the field of minimal residual disease (MRD) diagnostics, which is progressively more applied for the evaluation of treatment effectiveness in patients with a hematological malignancy, such as B-cell precursor acute lymphoblastic leukemia (BCP-ALL), B-cell chronic lymphocytic leukemia (B-CLL), and multiple myeloma (MM). Provided are unique reagent compositions with carefully selected and thoroughly tested combinations of antibodies, for ?8-color flow cytometric stainings as well as for 10-color and 12-color flow cyometric stainings, which can reach sensitivities of at least 10?4, even down to 10?5. Also provided are diagnostic kits and methods for detecting MRD.Type: GrantFiled: November 14, 2017Date of Patent: December 29, 2020Assignee: Erasmus University Medical Center RotterdamInventors: Jacobus Johannes Maria van Dongen, José Alberto Orfao de Matos Correia e Vale, Juan Alejandro Flores Montero, Julia Maria Almeida Parra, Vincent Henricus Johannes Van der Velden, Sebastian Böttcher, Anthonie Willem Langerak, Ester Mejst{hacek over (r)}íková, Tomasz Szczepański, Matthias Ritgen, Paulo Jorge Monteiro Da Silva Lucio
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Patent number: 10465447Abstract: A cutting element configured to mitigate spalling on a front cutting face thereof. The cutting element include a diamond table having the front cutting face defined thereon and at least one recess defined on the front cutting face of the diamond table. The at least one recess has a width within a range of 25.0 ?m to 650 ?m and a depth within a range of 25.0 ?m to 600 ?m. Methods of forming a cutting element configured to mitigate spalling on the front cutting face thereof. The methods including forming at least one recess on a front cutting face of a diamond table to have a width within a range of 25.0 ?m to 650 ?m and a depth within a range of 25.0 ?m to 600 ?m. Method of using a cutting element configured to mitigate spalling on the front cutting face thereof.Type: GrantFiled: March 12, 2015Date of Patent: November 5, 2019Assignee: Baker Hughes, a GE company, LLCInventors: David A. Stockey, Suresh G. Patel, Alejandro Flores, Konrad Izbinski
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Patent number: 10428591Abstract: A cutting element for an earth-boring tool includes a substrate and volume of superabrasive material positioned on the substrate. The volume of superabrasive material includes a cutting face having at least one recess extending into the volume of superabrasive material and/or at least one protrusion extending outward from the volume of superabrasive material. The volume of superabrasive material includes a first chamfer surface having a peripheral edge and a radially innermost edge. The peripheral edge of the first chamfer surface is located proximate a cutting edge of the volume of superabrasive material. A radial width of the first chamfer surface is between about 0.002 inch and about 0.045 inch. The volume of superabrasive material also includes a second chamfer surface having a peripheral edge and a radially innermost edge. The peripheral edge of the second chamfer surface is located adjacent the radially innermost edge of the first chamfer surface.Type: GrantFiled: May 3, 2017Date of Patent: October 1, 2019Assignee: Baker Hughes IncorporatedInventors: Suresh G. Patel, David A. Stockey, Alejandro Flores, Anthony A. DiGiovanni, Danny E. Scott, Leroy W. Ledgerwood, III
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Patent number: 10282495Abstract: Methods of evaluating prototype cutting elements for earth-boring tools may involve generating first and second sets of virtual representations of cutting elements from first and second sets of used cutting elements. First and second sets of measures of damage corresponding to damage for each of the first and second sets set of virtual representations of cutting elements may be determined. A best-performing set of cutting elements from the first and second sets of used cutting elements according to the first and second sets of measures of damage may be identified by performing a statistical analysis.Type: GrantFiled: July 27, 2015Date of Patent: May 7, 2019Assignee: Baker Hughes IncorporatedInventors: Konrad T. Izbinski, Aaron J. Dick, Nicholas J. Lyons, Alejandro Flores, Suresh G. Patel, Jarod DeGeorge
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Patent number: 10209245Abstract: The invention relates to the field of flow cytometry and more particularly to a panel of antibody reagents conjugated to fluorescent compounds. Provided are reagent compositions, comprising at least eight distinct fluorochrome-conjugated antibodies comprising a set of at least there identification antibodies for the identification of a leukocyte population of interest and at least four characterization antibodies for further characterization and/or classification of said leukocyte population. Also provided are kits and methods related to the reagent compositions.Type: GrantFiled: December 20, 2017Date of Patent: February 19, 2019Assignee: Erasmus University Medical Center RotterdamInventors: Jacobus Johannes Maria van Dongen, Jose Alberto Orfao de Matos Correia e Vale, Juan Alejandro Flores-Montero, Julia Maria Almeida Parra, Vincent Henricus Johannes van der Velden, Sebastian Böttcher, Andrew Craig Rawstron, Ruth Mary de Tute, Ludovic Bernard Simon Lhermitte, Vahid Asnafi, Ester Mejstrikova, Tomasz Szczepanski, Paulo Jorge Monteiro Da Silva Lucio, Marta Martín Ayuso, Carlos Eduardo Pedreira
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Patent number: 10167388Abstract: The present invention is related to formulations consisting of block copolymers ?,?-di-aryl or alkyl sulfonates of poly(ethylene oxide)w-poly(propylene oxide)-poly(ethylene oxide)w of bis-ammonium and block copolymers ?,?-di-amine of poly(ethylene oxide)w-poly(propylene oxide)-poly(ethylene oxide)w, that are effective in the dewatering and desalting crude whose specific gravities are within the range of 14 to 23°API.Type: GrantFiled: August 3, 2017Date of Patent: January 1, 2019Assignee: INSTITUTO MEXICANO DEL PETROLEOInventors: Eugenio Alejandro Flores Oropeza, Cesar Andres Flores Sandoval, Reyna Reyes Martinez, Jose Gonzalo Hernandez Cortez, Alfonso Lopez Ortega, Laura Veronica Castro Sotelo, Fernando Alvarez Ramirez, Arquimedes Estrada Martinez, Flavio Salvador Vazquez Moreno
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Patent number: 10125226Abstract: A chemical synthesis process is provided for the functionalization of monodispersed triblock copolymer (POEw-POPy-POEw) with secondary or tertiary amines at a semi-industrial level in glass reactors having a capacity between 1 L and 100 L. The process includes two stages where the first stage uses an alkylsulfonyl or arylsulfonyl chloride to obtain better leaving groups, and the second stage is the nucleophilic substitution with secondary or tertiary amines, to obtain the bifunctionalized triblock copolymers. The main advantage for this process is to reduce the quantity of unitary process done in each stage, the optimization of reaction times, and the stoichiometric relationships.Type: GrantFiled: June 4, 2014Date of Patent: November 13, 2018Assignee: INSTITUTO MEXICANO DEL PETROLEOInventors: Cesar Andres Flores Sandoval, Eugenio Alejandro Flores Oropeza, Alfonso Lopez Ortega, Jose Gonzalo Hernandez Cortez, Aristeo Estrada Buendia, Laura Veronica Castro Sotelo, Reyna Reyes Martinez, Fernando Alvarez Ramirez, Arquimedes Estrada Martinez, Flavio Salvador Vazquez Moreno
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Patent number: 10047302Abstract: Compositions consisting of block copolymers ?,?-di-aryl or alkyl sulfonates of poly(ethylene oxide)w-poly(propylene oxide)-poly(ethylene oxide)w of bis-ammonium and block copolymers ?,?-di-amine of poly(ethylene oxide)w-poly(propylene oxide)-poly(ethylene oxide)w, are provided that are effective in the dewatering and desalting crude oils whose specific gravities are within the range of 14 to 20° API. A method of dewatering and desalting heavy crude oil adds a mixture of the copolymer bifunctionalized with an aliphatic or aromatic secondary amine and a copolymer bifunctionalized with an aliphatic or aromatic tertiary amine.Type: GrantFiled: July 14, 2017Date of Patent: August 14, 2018Assignee: INSTITUTO MEXICANO DEL PETROLEOInventors: Eugenio Alejandro Flores Oropeza, Cesar Andres Flores Sandoval, Reyna Reyes Martinez, Jose Gonzalo Hernandez Cortez, Alfonso Lopez Ortega, Laura Veronica Castro Sotelo, Fernando Alvarez Ramirez, Arquimedes Estrada Martinez, Flavio Salvador Vazquez Moreno
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Publication number: 20180201877Abstract: Disclosed are fragrance-enhanced cleaning compositions including a mixture of a linear alkyLbenzene sulfonate (LAS) and a sodium lauryl ether sulfate (SLES), wherein the mixture is present in the cleaning composition in an amount of about 1%-2% by weight and wherein a weight ratio of LAS:SLES is about 3:1 to about 1:1 or about 6:1 to about 4:1; and a fragrance. Methods of preparing and using the present cleaning compositions are also disclosed. In addition, methods of formulating a cleaning composition having an enhanced fragrance performance are provided.Type: ApplicationFiled: July 10, 2015Publication date: July 19, 2018Applicant: Colgate-Palmolive CompanyInventors: Jorge Antonio MALDONADO ORTEGA, Edna AMBUNDO, Jose Alejandro FLORES SANABRIA, Antonla de la Cruz RAMIREZ MENDEZ, Maria Eugenia ROJO DIEGUEZ, Luis Javier RIVERA CRUZ
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Publication number: 20180180597Abstract: The invention relates to the field of flow cytometry and more particularly to a panel of antibody reagents conjugated to fluorescent compounds. Provided are reagent compositions, comprising at least eight distinct fluorochrome-conjugated antibodies comprising a set of at least there identification antibodies for the identification of a leukocyte population of interest and at least four characterization antibodies for further characterization and/or classification of said leukocyte population. Also provided are kits and methods related to the reagent compositions.Type: ApplicationFiled: December 20, 2017Publication date: June 28, 2018Inventors: Jacobus Johannes Maria van Dongen, José Alberto Orfao de Matos Correia e Vale, Juan Alejandro Flores-Montero, Julia Maria Almeida Parra, Vincent Henricus Johannes van der Velden, Sebastian Böttcher, Andrew Craig Rawstron, Ruth Mary de Tute, Ludovic Bernard Simon Lhermitte, Vahid Asnafi, Ester Mejstríková, Tomasz Szczepanski, Paulo Jorge Monteiro Da Silva Lucio, Marta Marin Ayuso, Carlos Eduardo Pedreira