Abstract: The present disclosure provides for, among other things, methods and systems for detecting, diagnosing, predicting, monitoring, screening for, staging, and/or providing survival prognosis for advanced adenoma and/or colorectal cancer using DNA methylation markers. For example, described herein are DNA methylation markers that enable categorization and prognosis evaluation of advanced adenoma (AA) and/or colorectal cancer (CRC) patients with high accuracy from human biospecimens.

Abstract: Disclosed are techniques, and related systems, for developing and implementing a unified framework for quantifying risk in machine learning models, such as deep neural networks. The framework can be easy-to-use and flexible to apply to different types of machine learning models. The framework can be used to automatically assess different forms of risk in parallel, including but not limited to aleatoric uncertainty, epistemic uncertainty, and/or vacuitic uncertainty. To that end, the disclosed framework provides wrappers that compose different automatic risk assessment algorithms. The obtained risk estimates can be used, for example, for: providing a deeper insight into decision boundaries of neural networks; performing downstream tasks by integrating the risk estimates back into a learning lifecycle for the model to improve robustness and generalization; and/or improving safety by identifying potential model failures based on the risk values.

Abstract: The invention relates to power transfer device for inductively charging a water-bound vehicle, comprising: a power transfer part comprising a primary conductor arrangement; and at least one connecting member which has a first connecting portion for connecting the power transfer device to the surroundings and a second connecting portion for connecting the connecting member to the power transfer part; wherein the connecting member has a least one resilient portion that is configured to absorb shocks exerted onto the power transfer part. Further, the invention relates to a mooring area, comprising a respective power transfer device.

Abstract: A floating platform for high-power wind turbines, comprising a concrete substructure, said concrete substructure forming the base of the platform, which remains semi-submerged in the operating position, and consisting of a square lower slab on which a series of beams and five hollow reinforced concrete cylinders are constructed, distributed at the corners and the center of said lower slab; a metal superstructure supported on the concrete substructure and forming the base for connection with the wind turbine tower, said tower being coupled at the center thereof; and metal covers covering each of the cylinders, on which the metal superstructure is supported and to which vertical pillars are secured, linked together by beams, which join at the central pillar by an element whereon the base of the wind turbine tower is secured.

Abstract: Systems, computer program products, and methods are described herein for synchronizing dataflow migration between technical environments. The present invention is configured to identify one or more resources in a source environment for migration from the source environment to a target environment; capture, using a resource assessment engine, one or more dependencies associated with the one or more resources; generate a migration load based on at least the one or more resources identified in the source environment and the one or more dependencies associated with the one or more resources; generate a snapshot of the source environment based on at least the migration load, wherein the snapshot comprises at least the one or more resources and the one or more dependencies; and store the snapshot of the source environment in a snapshot database repository.

Abstract: The present disclosure primarily relates to certain agrochemically active herbicidal combinations comprising (A) diflufenican and (B) mesotrione. The disclosure further relates to the use of these combinations for controlling weeds, in particular for controlling resistant weeds, and to corresponding methods.

Abstract: The present disclosure relates to the technical field of crop protection. The present disclosure primarily relates to microcapsules comprising a polymeric shell wall and a water-immiscible core material comprising (i) an acetamide herbicide, (ii) diflufenican and (iii) an organic non-polar solvent. The present disclosure also relates to herbicidal compositions comprising these microcapsules, methods for preparing these microcapsules and methods of using these microcapsules and herbicidal compositions for controlling weeds.

Abstract: A target trial dataset with trial covariates and clinical outcome data is obtained from a plurality of human patients. An artificial patient dataset is generated by using distributions of one or more corresponding covariates and their correlations derived from the set of trial covariates, and filtering the artificial patient dataset, with each data record of the artificial patient dataset storing covariates of a respective artificial patient. The artificial patient dataset is provided to a disease progression model to generate a simulated dataset with simulated covariates and clinical outcome data for artificial patients not receiving experimental treatment. A treatment effect of a drug is determined by analyzing the trial dataset and the simulated dataset together to incorporate the simulated dataset, wherein the simulated dataset is given a weight in comparison to a control arm of the trial dataset, with the weight based on at least a maximum weight value.

Abstract: Systems, computer program products, and methods are described herein for synchronizing dataflow migration between technical environments. The present invention is configured to identify one or more resources in a source environment for migration from the source environment to a target environment; capture, using a resource assessment engine, one or more dependencies associated with the one or more resources; generate a migration load based on at least the one or more resources identified in the source environment and the one or more dependencies associated with the one or more resources; generate a snapshot of the source environment based on at least the migration load, wherein the snapshot comprises at least the one or more resources and the one or more dependencies; and store the snapshot of the source environment in a snapshot database repository.

Abstract: Disclosed herein are regulated power supplies. The power source delivers power to a system load and includes battery units. The power source also includes power flow devices coupled to the battery units that are configured to provide power from the battery units to the system load. Each power flow device corresponds to a respective one of the battery units and includes a one direction current flow device connected in series with a current regulator between the respective battery unit and the system load.

Abstract: A method of assembly includes forming a first member to include a plurality of elastically deformable locating protrusions extending outward from an exterior surface of the first member. A locating protrusion is an elongate member having an arcuate portion, a first linear leg portion extending from a first arc end, and a second leg portion extending from a second arc end. The method additionally includes forming a second member to include a plurality of elastically deformable compression features. The locating protrusions are inserted in press fit engagement with the plurality of compression features such that the first member and the second member are secured relative to each other and the average of the elastic deformation between all of the plurality of locating protrusions and all of the plurality of compression features precisely aligns the first member relative to the second member.

Abstract: Disclosed herein are regulated power supplies. The power source delivers power to a system load and includes battery units. The power source also includes power flow devices coupled to the battery units that are configured to provide power from the battery units to the system load. Each power flow device corresponds to a respective one of the battery units, and includes a one direction current flow device connected in series with a current regulator between the respective battery unit and the system load.

Abstract: Disclosed are nutritional compositions including 2?-fucosyllactose (2?-FL) in combination with lutein and RRR-alpha-tocopherol. The nutritional compositions are useful for improving at least one of gut function, health, and development in an individual. In certain embodiments, the nutritional compositions can improve growth or maturation of the gut, as well as promote a healthy balance of beneficial bacteria in the gastrointestinal tract thereby treating and/or preventing formula intolerance or other gastrointestinal diseases and/or disorders resulting from suboptimal gastrointestinal flora population/balance.

Abstract: One aspect of the invention refers to an oral pharmaceutical composition comprising the MDM2-antagonist of formula I in a dose range of 30 mg to 45 mg for use in the treatment of cancer, wherein this oral pharmaceutical composition is administered in a treatment cycle of once every three weeks (D1 q3w), wherein this treatment cycle of once every three weeks (D1 q3w) may be repeated that many times as considered beneficial for the patient from a medical point of view. Another aspect of the invention refers to an MDM2-antagonist of formula I for use in the first line systemic treatment (primary treatment) of dedifferentiated liposarcoma. A further aspect of the invention refers to the use of the MDM2-antagonist of formula I for the manufacture of a medicament for the treatment of a p53-wildtype and non-MDM2-amplified form of cancer.

Abstract: Disclosed herein are regulated power supplies. The power source delivers power to a system load and includes battery units. The power source also includes power flow devices coupled to the battery units that are configured to provide power from the battery units to the system load. Each power flow device corresponds to a respective one of the battery units, and includes a one direction current flow device connected in series with a current regulator between the respective battery unit and the system load.

Abstract: Methods of reducing injury to crop foliage and achieving weed control using encapsulated acetamide herbicides in pre-plant or preemergence crop plant applications are described. A composition comprising a first population of a particulate microencapsulated acetamide herbicide and a second population of a particulate microencapsulated acetamide herbicide is described wherein the application mixture exhibits a bimodal acetamide release profile. The compositions provide reduced crop injury through controlled herbicide release.

Abstract: A lift assembly includes an upper rail. A plurality of rail flanges extend from the upper rail. The lift assembly further includes a plurality of combustion can support assemblies spaced apart from one another. Each combustion can support assembly of the plurality of combustion can support assemblies includes a support flange slidably coupled to a rail flange of the plurality of rail flanges, an outer sleeve, and an inner sleeve assembly configured to removably couple to a combustion can of the turbomachine. Each combustion can support assembly of the plurality of combustion can support assemblies defines a cylindrical coordinate system having an axial direction, a radial direction, and a circumferential direction. Each combustion can support assembly of the plurality of support assemblies is configured to move along any of the axial direction, the radial direction, or the circumferential direction relative to the upper rail.

Abstract: Systems, computer program products, and methods are described herein for synchronizing dataflow migration between technical environments. The present invention is configured to identify one or more resources in a source environment for migration from the source environment to a target environment; capture, using a resource assessment engine, one or more dependencies associated with the one or more resources; generate a migration load based on at least the one or more resources identified in the source environment and the one or more dependencies associated with the one or more resources; generate a snapshot of the source environment based on at least the migration load, wherein the snapshot comprises at least the one or more resources and the one or more dependencies; and store the snapshot of the source environment in a snapshot database repository.

Abstract: Disclosed herein are regulated power supplies. The power source delivers power to a system load and includes battery units. The power source also includes power flow devices coupled to the battery units that are configured to provide power from the battery units to the system load. Each power flow device corresponds to a respective one of the battery units, and includes a one direction current flow device connected in series with a current regulator between the respective battery unit and the system load.

Abstract: A system for providing information about presence in a space includes a movement sensor for generating a signal upon detecting movement; and a presence sensor for generating a signal upon detecting presence, being a temperature-based matrix sensor having an array of sensing elements. The system further includes a processing and/or control component in communication with the movement and presence sensors, configured to generate a presence signal upon receiving the first and/or second signals; and configured to obtain background information of the presence detection field. The information includes reference temperature values and are obtained upon the movement sensor not detecting movement and/or the presence sensor detecting presence. For each sensing element with presence, using the measured temperature value of surrounding sensing elements not having presence.