Abstract: Described here are devices, systems, and methods for applying pulsed or modulated electric fields to tissue. In some variations, a device may comprise a first elongate body comprising a lumen, a second elongate body at least partially positioned within the lumen, and an expandable member rolled about the second elongate body. The expandable member may comprise an inner end coupled to the second elongate body, an outer end coupled to the first elongate body, and an electrode array.

Abstract: A retrieval catheter and methods of use are described for removing a heart valve therapy such as a leaflet clip or artificial leaflet cord. The retrieval catheter can include a cutting element and a basket, piercing element, clamping mechanism, or similar grasping device. The method includes delivering a catheter to the region of the heart valve therapy and then manipulating the catheter and associated instruments to cut tissue as necessary and then remove the heart valve therapy and withdraw the catheter.

Abstract: According to an aspect, a penile implant includes a first member having a coupling portion and a locking portion and a second member having a coupling portion and a locking portion The coupling portion of the first member is configured to engage the coupling portion of the second member to movably couple the first member to the second member such that the first member is configured to be placed in a first position with respect to the second member and a second position with respect to the second member. The locking portion of the first member is configured to engage the locking portion of the second member help retain the first member in its second position with respect to the second member.

Abstract: According to an aspect, an implant includes a sheath defining a lumen, a cable member disposed within the lumen defined by the sheath, and a tensioner. The tensioner is configured to engage the cable to apply tension to the sheath.

Abstract: According to an aspect, a penile implant includes a first member having a coupling portion and a locking portion and a second member having a coupling portion and a locking portion The coupling portion of the first member is configured to engage the coupling portion of the second member to movably couple the first member to the second member such that the first member is configured to be placed in a first position with respect to the second member and a second position with respect to the second member. The locking portion of the first member is configured to engage the locking portion of the second member help retain the first member in its second position with respect to the second member.

Abstract: According to an aspect, an implant includes a sheath defining a lumen, a cable member disposed within the lumen defined by the sheath, and a tensioner. The tensioner is configured to engage the cable to apply tension to the sheath.

Abstract: A retrieval catheter and methods of use are described for removing a heart valve therapy such as a leaflet clip or artificial leaflet cord. The retrieval catheter can include a cutting element and a basket, piercing element, clamping mechanism, or similar grasping device. The method includes delivering a catheter to the region of the heart valve therapy and then manipulating the catheter and associated instruments to cut tissue as necessary and then remove the heart valve therapy and withdraw the catheter.

Abstract: According to an aspect, a penile implant includes a first member having a coupling portion and a locking portion and a second member having a coupling portion and a locking portion The coupling portion of the first member is configured to engage the coupling portion of the second member to movably couple the first member to the second member such that the first member is configured to be placed in a first position with respect to the second member and a second position with respect to the second member. The locking portion of the first member is configured to engage the locking portion of the second member help retain the first member in its second position with respect to the second member.

Abstract: Described here are devices, systems, and methods for applying pulsed or modulated electric fields to tissue. In some variations, a device may comprise a first elongate body comprising a lumen, a second elongate body at least partially positioned within the lumen, and an expandable member rolled about the second elongate body. The expandable member may comprise an inner end coupled to the second elongate body, an outer end coupled to the first elongate body, and an electrode array.

Abstract: According to an aspect, a penile implant includes a first member having a coupling portion and a locking portion and a second member having a coupling portion and a locking portion. The coupling portion of the first member is configured to engage the coupling portion of the second member to movably couple the first member to the second member such that the first member is configured to be placed in a first position with respect to the second member and a second position with respect to the second member. The locking portion of the first member is configured to engage the locking portion of the second member help retain the first member in its second position with respect to the second member.

Abstract: According to an aspect, an implant includes a sheath defining a lumen, a cable member disposed within the lumen defined by the sheath, and a tensioner. The tensioner is configured to engage the cable to apply tension to the sheath.

Abstract: According to an aspect, an implant includes a sheath defining a lumen, a cable member disposed within the lumen defined by the sheath, and a tensioner. The tensioner is configured to engage the cable to apply tension to the sheath.

Abstract: According to an aspect, a penile implant includes a first member having a coupling portion and a locking portion and a second member having a coupling portion and a locking portion. The coupling portion of the first member is configured to engage the coupling portion of the second member to movably couple the first member to the second member such that the first member is configured to be placed in a first position with respect to the second member and a second position with respect to the second member. The locking portion of the first member is configured to engage the locking portion of the second member help retain the first member in its second position with respect to the second member.

Abstract: According to an aspect, an implant includes a sheath defining a lumen, a cable member disposed within the lumen defined by the sheath, and a tensioner. The tensioner is configured to engage the cable to apply tension to the sheath.

Abstract: Methods and devices for deploying an endoluminal implant in a curved vessel. The devices include steerable catheters having a control member that extends to the distal end and operates to bend the catheter. In other cases, the stent includes a longitudinal adjustment member attached near the leading edge of the stent and operates to shorten or lengthen the stent and thereby induce a curvature. The stent is carried in a distal region of the catheter that is advanced into a curved region of a vessel. The catheter is bent and/or the stent is curved using the longitudinal adjustment member, and the stent is deployed to achieve uniform wall contact with the endoluminal surface of the vessel at the lesser curvature.

Abstract: A medical graft connector or plug is made, for example, by cutting end portions of a tube of highly elastic material axially at numerous locations spaced circumferentially around the tube to produce a plurality of fingers which extend axially from each end of an uncut medial portion of the tube. The fingers are deflected radially outwardly from the medial portion and set in that condition. For a graft connector, the medial portion is coaxially connected to an end portion of a tubular graft. The connector is then installed through an aperture in the side wall of a patient's tubular body conduit, for example, by using a delivery tube in which the fingers are elastically deflected back to approximately their initial positions. When the delivery conduit is withdrawn from the connector, the fingers spring out to engage the inner and outer surfaces of the body conduit wall.

Abstract: A medical graft connector or plug is made, for example, by cutting end portions of a tube of highly elastic material axially at numerous locations spaced circumferentially around the tube to produce a plurality of fingers which extend axially from each end of an uncut medial portion of the tube. The fingers are deflected radially outwardly from the medial portion and set in that condition. For a graft connector, the medial portion is coaxially connected to an end portion of a tubular graft. The connector is then installed through an aperture in the side wall of a patient's tubular body conduit, for example, by using a delivery tube in which the fingers are elastically deflected back to approximately their initial positions. When the delivery conduit is withdrawn from the connector, the fingers spring out to engage the inner and outer surfaces of the body conduit wall.

Abstract: A medical graft connector for connecting an end of a tubular graft conduit to a side wall of a patient's existing tubular body conduit via an aperture in the side wall thereof has a first plurality of fingers configured to engage an interior surface of the side wall of the existing conduit. A second plurality of fingers is configured to engage an exterior surface of the side wall of the existing conduit. A third plurality of fingers is received in an interior lumen of the graft conduit, and a fourth plurality of fingers is configured to pierce the graft conduit. The connector is radially deformable between a first size and a second size.

Abstract: A medical graft connector for connecting an end of a tubular graft conduit to a side wall of a patient's existing tubular body conduit via an aperture in the side wall thereof has a plurality of fingers configured to engage an interior surface of the side wall of the existing conduit. At least one of the plurality of fingers has an end portion configured to pierce the graft conduit. The plurality of fingers is substantially radially aligned with respect to a longitudinal axis and wherein the connector is radially enlargeable between a first size and a second size.

Abstract: A medical graft connector or plug is made, for example, by cutting end portions of a tube of highly elastic material axially at numerous locations spaced circumferentially around the tube to produce a plurality of fingers which extend axially from each end of an uncut medial portion of the tube. The fingers are deflected radially outwardly from the medial portion and set in that condition. For a graft connector, the medial portion is coaxially connected to an end portion of a tubular graft. The connector is then installed through an aperture in the side wall of a patient's tubular body conduit, for example, by using a delivery tube in which the fingers are elastically deflected back to approximately their initial positions. When the delivery conduit is withdrawn from the connector, the fingers spring out to engage the inner and outer surfaces of the body conduit wall.