Patents by Inventor Alex Bruce MacDonald

Alex Bruce MacDonald has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Vaccine comprising anti-idiotypic antibody to chlamydia GLXA and process
    Patent number: 5840297
    Abstract: A genus specific chlamydia vaccine is provided which comprises an anti-idiotype antibody capable of producing in an animal an anti-anti-idiotypic antibody which recognizes a glycoplipid exoantigen (GLXA) of chlamydia. The vaccine is produced by producing an idiotypic antibody to GLXA which, in turn, is utilized t produce the anti-idiotypic antibody comprising the vaccine.
    Type: Grant
    Filed: March 19, 1993
    Date of Patent: November 24, 1998
    Assignees: Johns Hopkins University, University of Massachusetts
    Inventors: Alex Bruce MacDonald, Ling-Ling An, Elizabeth Sutton-Stuart, Judith A. Whittum-Hudson
  • Method for diagnosing a patient for chlamydia
    Patent number: 5716793
    Abstract: A method of detecting chlamydia in a extracellular sample is provided which comprises contacting the sample with an idiotypic antibody to GLXA to form an immunocomplex and detecting the immunocomplex.
    Type: Grant
    Filed: March 17, 1995
    Date of Patent: February 10, 1998
    Assignee: Animal House, Inc.
    Inventors: Alex Bruce MacDonald, Elizabeth S. Stuart, Ling Ling An, Myron D. Whipkey
  • Oral vaccine comprising anti-idiotypic antibody to chlamydia glycolipid exoantigen and process
    Patent number: 5656271
    Abstract: A genus specific chlamydia oral or injectable vaccine is provided which comprises an anti-idiotype antibody capable of producing in an animal an anti-idiotypic antibody or Fab fragment thereof enclosed in microspheres formed of a pharmacologically acceptable polymer is capable of producing in an animal an anti-anti-idiotypic immune response (serum antibody, secretory antibody or T-cell responsee) which recognizes a glycolipid exoantigen (GLXA) of chlamydia. The oral or injectable vaccine is produced from an idiotypic antibody to GLXA which, in turn, is utilized to produce the anti-idiotypic antibody.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: August 12, 1997
    Assignees: The Johns Hopkins University, University of Massachusetts
    Inventors: Alex Bruce MacDonald, Judith A. Whittum-Hudson, William Mark Saltzman