Abstract: A microkeratome blade for use for the removal of the epithelial layer and underlying Basement Membrane while leaving a smooth and undisturbed Bowman's Membrane in preparation for a laser refractive surgical procedure. The blade is capable of cutting through the epithelial layer and Basement Membrane, but not capable of cutting through Bowman's Membrane.

Abstract: A refractive surgical procedure method using microkeratome blade for use for the removal of the epithelial layer and underlying Basement Membrane while leaving a smooth and undisturbed Bowman's Membrane in preparation for a laser refractive surgical procedure. The blade is capable of cutting through the epithelial layer and Basement Membrane, but not capable of cutting through Bowman's Membrane. Prior to removing the epithelium, a solution suitable for reducing the adhesion of the epithelium is applied to the eye. Following surgery, a customized contact lens is placed on the eye. The contact lens may contain an agent to assist in the regeneration of the epithelium.

Abstract: A microkeratome blade for use for the removal of the epithelial layer and underlying Basement Membrane while leaving a smooth and undisturbed Bowman's Membrane in preparation for a laser refractive surgical procedure. The blade is capable of cutting through the epithelial layer and Basement Membrane, but not capable of cutting through Bowman's Membrane.

Abstract: A method for the removal of the epithelial layer and underlying Basement Membrane while leave a smooth and undisturbed Bowman's Membrane in preparation for a laser refractive surgical procedure. The method of the present invention uses a microkeratome having a blade that is capable of cutting through the epithelial layer and Basement Membrane, but not capable of cutting through Bowman's Membrane.

Abstract: A method and system are described for performing photorefractive keratectomy procedure employing pulses of photoablative radiation to selectively ablate corneal tissue of a patient's eye in an ablation zone on the anterior corneal surface to produce a desired refractive correction in the corneal tissue. The method and system employ control of the effect of ocular fluid at the corneal surface so as to reduce the disturbance of such fluid on the desired ablation process while maintaining hydration of the corneal tissue.

Abstract: The invention is a system and method for modifying the corneal curvature by irradiating the cornea to deliver thermal energy to the stroma. The system includes multiple irradiation ports for introducing electromagnetic radiation of a wavelength suitable for absorption in the stroma; positioning means, such as a hemi-spherical dome with several tracks for positioning the irradiation ports, respectively, at locations of a preselected geometric pattern relative to the pretreated cornea, the geometric pattern being selected to correspond to a desired modified shape of the cornea; transmission means adapted to deliver controlled amounts of the radiation from a radiation source to each of the irradiation ports; and the irradiation ports, positioned at the locations of the geometric pattern, constructed to introduce the radiation to treatment volumes of the stroma in a cooperative manner to induce desired shrinkage of the collagenous stromal tissue and cause change in the corneal curvature.

Abstract: Methods and apparatus for determining the depth of excision generated by a material removal process, for determining the thickness of unablated material below the excision or incision, and for providing endpoint control of a material removal process utilize acoustic transducers for measuring the time delay between a first acoustic pulse resulting from material removal and a second acoustic pulse reflected from a distal surface or boundary layer of the material. The time delay between the two pulses detected by the transducer provides a measure of excision depth and of the depth of material below the excision. Endpoint control is provided by terminating material removal when a selected excision depth is detected. The invention can be used, for example, as a real-time monitor of excision depth and residual lamella thickness under the excision during laser corneal surgery.