Abstract: The disclosure relates to USP30 Inhibitor Compounds, pharmaceutically acceptable salts thereof, pharmaceutical compositions comprising same, and medical uses involving same.

Abstract: A human-body-signal collection device (10). The human-body-signal collection device (10) includes a reference electrode (210), a first electrode (220) and a second electrode (230), an adjusting and generating device (30), a first collection device (40), and a first feedback device (50). The first electrode (220) outputs the first signal. The second electrode (230) outputs the second signal. The adjusting and generating device (30) is connected to the reference electrode (210) to output a reference signal to the reference electrode (210). The first collection device (40) collects the first signal and the second signal, and generates a first potential-difference signal based on the first signal and the second signal. The first feedback device (50) is connected to the first collection device (40) and the adjusting and generating device respectively.

Abstract: Provided is a method for preparing Rebaudioside J using an enzymatic method, comprising using rebaudioside A as a substrate, and making the substrate, in the presence of a glycosyl donor, react under the catalysis of a UDP-glycosyltransferase-containing recombinant cell and/or UDP-glycosyltransferase prepared therefrom to generate Rebaudioside J.

Abstract: Embodiments are disclosed for a method. The method includes generating a correction datastore indicating shifts in magnitude representing corresponding characters that uniquely identify hardware comprising a computer processing chip. The method further includes generating security masks based on a correction file. Additionally, the method includes using a correction process for the computer processing chip. The generated security masks include corresponding overlays representing the shifts in magnitude with respect to corresponding product masks for the computer processing chip. The method also includes generating the computer processing chip using the security masks and the product masks.

Abstract: This disclosure describes a payload pipeline system that, as part of an inter-network facilitation system, can facilitate digital payload throughput between network components using a staggered payload relayer. For example, the disclosed systems utilize custom tooling to implement a staggered payload relayer as an intelligent conduit or pipeline that operates as a publisher-subscriber paradigm system (as opposed to a data stream system). In some cases, the disclosed systems can utilize synchronous or asynchronous communication to receive digital payloads for events from publisher network components and to make the digital payloads available within a payload queue maintained by the staggered payload relayer (for access by subscriber network components).

Abstract: A textile includes: (1) a matrix; and (2) particulate fillers dispersed within the matrix. The textile has a transmittance of infrared radiation at a wavelength of 9.5 ?m of at least about 40%, and the textile has a weighted average reflectivity of radiation over a wavelength range of 0.3 ?m to 2 ?m of at least about 40%.

Abstract: A user equipment (UE) is configured to transmit, to a cellular carrier, a request to activate the UE with the cellular carrier. The UE is also configured to, in response to receiving an authentication request for authenticating a user of the UE, transmit, to the cellular carrier, information identifying another UE and authentication information for authenticating the user ; prompt the user, via a display of the UE, to provide, to an input system of the UE, verification information transmitted to the other UE; transmit, to the cellular carrier, the verification information; and in response to validation of the verification information by the cellular carrier, receive an embedded subscriber identity module (eSIM) subscription transferred from the other UE.

Abstract: Resource state validation may be performed for access management policies by an identity and access management system. An access management policy associated with an account for network-based services may be received and validated according to resource state obtained for resources associated with the account. A correction for a portion of the access management policy may be identified according to the validation and provided via an interface for the identity and access management system.

Abstract: A search system performs a federated search across multiple databases and generates a ranked combined list of found genealogical records. The system receives a user query with one or more specified characteristics. The system may determine expanded characteristics derived from the specified characteristics. The system searches the various databases with the characteristics retrieving records according to the characteristics. The system combines the retrieved records and ranks them using a machine learning model. The machine learning model is configured to assign a weight to the records returned from each of the genealogical databases based on the characteristics specified in the user query. The machine learning model may be trained by any combination of one or more of: a Nelder-Mead method, a coordinate ascent method, and a simulated annealing method. The ranked combined results are provided in response to the user query.

Abstract: There is a need for faster and more accurate predictive data analysis steps/operations. This need can be addressed by, for example, techniques for efficient predictive data analysis steps/operations. In one example, a method includes identifying a first predictive entity embedding for the first predictive entity and a second predictive entity embedding for a second predictive entity; determining, using a similarity determination machine learning model and based at least in part on the first predictive entity embedding and the second predictive entity embedding, a predicted cross-entity similarity measure; and performing one or more prediction-based actions based at least in part on the predicted cross-entity similarity measure.

Abstract: The present invention is a material roll support system operable to hold of a roll of material and a method relating thereto. The material roll support system comprises two independent holder units, each of which can support one side of a roll of material. The independent holder units may be fixedly or non-fixedly attached to a surface, or may be held in a position solely by gravity. The surface upon which an independent holder unit is positioned may be supports, such as posts or other surfaces, such that a roll of material can be held by the independent holder units in an area or environment that contains such supports and between such supports. The independent holder units can further be positioned at varying distances from each other and the material roll support system can thereby can be used to support rolls of materials of varying widths.

Abstract: Resource state validation may be performed for access management policies by an identity and access management system. An access management policy associated with an account for network-based services may be received and validated according to resource state obtained for resources associated with the account. A correction for a portion of the access management policy may be identified according to the validation and provided via an interface for the identity and access management system.

Abstract: Resource state validation may be performed for access management policies by an identity and access management system. An access management policy associated with an account for network-based services may be received and validated according to resource state obtained for resources associated with the account. A correction for a portion of the access management policy may be identified according to the validation and provided via an interface for the identity and access management system.

Abstract: A search system performs a federated search across multiple databases and generates a ranked combined list of found genealogical records. The system receives a user query with one or more specified characteristics. The system may determine expanded characteristics derived from the specified characteristics. The system searches the various databases with the characteristics retrieving records according to the characteristics. The system combines the retrieved records and ranks them using a machine learning model. The machine learning model is configured to assign a weight to the records returned from each of the genealogical databases based on the characteristics specified in the user query. The machine learning model may be trained by any combination of one or more of: a Nelder-Mead method, a coordinate ascent method, and a simulated annealing method. The ranked combined results are provided in response to the user query.

Abstract: In one embodiment, a method includes receiving, at a query field associated with a social network environment, a request from a first user of the social network environment, identifying a first set of objects associated with the online social network matching at least in part the character string of the request, determining a second set of objects based on the first set of objects, wherein each object in the second set of objects is conceptually relevant to at least one of the objects of the first set of objects, and sending, to the query field for display to the first user, the suggested queries responsive to the request, wherein at least one of the suggested queries comprises a references to one of the conceptually relevant objects in the second set of objects.

Abstract: The present invention is a material roll support system operable to hold of a roll of material and a method relating thereto. The material roll support system comprises two independent holder units, each of which can support one side of a roll of material. The independent holder units may be fixedly or non-fixedly attached to a surface, or may be held in a position solely by gravity. The surface upon which an independent holder unit is positioned may be supports, such as posts or other surfaces, such that a roll of material can be held by the independent holder units in an area or environment that contains such supports and between such supports. The independent holder units can further be positioned at varying distances from each other and the material roll support system can thereby can be used to support rolls of materials of varying widths.

Abstract: In one aspect of the present technique, a method for selecting between a plurality of electromagnetic sensors to correct for one or more field distortions includes, in the presence of an electromagnetic field, acquiring signals representative of the location of a plurality of electromagnetic sensors. The method further includes selecting between the signals from the plurality of electromagnetic sensors based on one or more quality metrics. In another aspect of the present technique, a system for selecting an optimum EM sensor to correct for one or more field distortions includes a plurality of EM sensors and an additional EM sensor for transmitting or receiving signals representative of the location of each of the plurality of EM sensors. The system further includes a controller configured to acquire signals representative of the location of the plurality of EM sensors, and select between the signals from the plurality of EM sensors based on one or more quality metrics.

Abstract: Systems, methods, and non-transitory computer-readable media can receive a plurality of content items. Tag information is generated for each content item of the plurality of content items. The tag information comprises one or more tags, and at least one tag for each content item is generated based on a machine learning technique. Query information is received from a first user. One or more content items of the plurality of content items is identified based on the query information and the tag information.

Abstract: Systems, methods, and non-transitory computer-readable media can receive a plurality of content items. Tag information is generated for each content item of the plurality of content items. The tag information comprises one or more tags, and at least one tag for each content item is generated based on a machine learning technique. Query information is received from a first user. One or more content items of the plurality of content items is identified based on the query information and the tag information.

Abstract: In one embodiment, a method includes accessing a first instance of content to be uploaded to a server, generating a second instance of the content from the first instance, automatically uploading to the server the second instance of the content, and automatically uploading to the server the first instance of the content in response to occurrence of a pre-determined upload condition. The first instance has a first file size and the second instance has a second file size that is smaller than the first file size. The upload of the second instance makes the content available for access at least in part by one or more second users at an immediate point in time. The upload of the first instance of the content makes the content available for access by the second users in an original version.