Patents by Inventor Alex Sele

Alex Sele has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 4327091
    Abstract: 3,4-Dihydro-2H-1,2-benzothiazine 1,1-dioxides of the formula ##STR1## wherein Ph represents a substituted or unsubstituted 1,2-phenylene radical, R represents a substituted or unsubstituted benzopyrone radical, and R.sub.1 represents hydrogen or a substituted or unsubstituted hydrocarbon radical of aliphatic character, and their salts, possess antiinflammatory properties and are useful as medicaments.
    Type: Grant
    Filed: January 28, 1980
    Date of Patent: April 27, 1982
    Assignee: Ciba-Geigy Corporation
    Inventors: Alex Sele, Pier G. Ferrini, Georges Haas, Knut A. Jaeggi, Alberto Rossi
  • Patent number: 4297358
    Abstract: New 4,7-phenanthroline derivatives of the formula (I) ##STR1## in which Ch represents an optionally substituted 5,6-quinolinylene radical of which the 6-position is joined to the --N(R.sub.E)-- group, andR represents an optionally esterified or amidated carboxy group,and in which eitherR.sub.A and R.sub.B together represent oxo,R.sub.C and R.sub.D together represent an additional link, andR.sub.E represents a radical R.sub.1 which is hydrogen, or an aliphatic, cycloaliphatic, araliphatic or heterocyclic-aliphatic radical, orR.sub.A represents an optionally etherified hydroxy group andR.sub.B together with R.sub.C and R.sub.D together with R.sub.E in each case represents an additional link,and salts of salt-forming compounds of the formula (I), compounds of the formula (I) or the salts thereof have anti-allergic properties. They can be prepared in accordance with processes known per se and may be used as active substances in pharmaceutical preparations.
    Type: Grant
    Filed: January 4, 1980
    Date of Patent: October 27, 1981
    Assignee: Ciba-Geigy Corporation
    Inventors: Georges Haas, Knut A. Jaeggi, Alberto Rossi, Alex Sele
  • Patent number: 4288450
    Abstract: The present invention relates to novel benzopyrane derivatives, especially 3-oxaloamino-4-oxo-4H-1-benzopyrane derivatives of the formula I ##STR1## in which Ph is substituted or unsubstituted 1,2-phenylene, R is free, esterified or amidated carboxyl and R.sub.1 is hydrogen or a substituted or substituted hydrocarbon radical, in the free from or in the form of a salt, exhibit antiallergic activities and are accordingly useful as active ingredients of antiallergic pharmaceutical preparations.
    Type: Grant
    Filed: January 7, 1980
    Date of Patent: September 8, 1981
    Assignee: Ciba-Geigy Corporation
    Inventors: Georges Haas, Alberto Rossi, Knut A. Jaeggi, Alex Sele
  • Patent number: 4216155
    Abstract: The present invention relates to novel benzopyrane derivatives, especially 3-oxaloamino-4-oxo-4H-1-benzopyrane derivatives of the formula I ##STR1## in which Ph is substituted or unsubstituted 1,2-phenylene, R is free, esterified or amidated carboxyl and R.sub.1 is hydrogen or a substituted or substituted hydrocarbon radical, in the free form or in the form of a salt, exhibit antiallergic activities and are accordingly useful as active ingredients of antiallergic pharmaceutical preparations.
    Type: Grant
    Filed: July 11, 1978
    Date of Patent: August 5, 1980
    Assignee: Ciba-Geigy Corporation
    Inventors: Georges Haas, Alberto Rossi, Knut A. Jaeggi, Alex Sele
  • Patent number: 4213980
    Abstract: 3,4-Dihydro-2H-1,2-benzothiazine 1,1-dioxides of the formula ##STR1## wherein Ph represents a substituted or unsubstituted 1,2-phenylene radical, R represents a substituted or unsubstituted benzopyrone radical, and R.sub.1 represents hydrogen or a substituted or unsubstituted hydrocarbon radical of aliphatic character, and their salts, possess antiinflammatory properties and are useful as medicaments.
    Type: Grant
    Filed: January 17, 1979
    Date of Patent: July 22, 1980
    Assignee: Ciba-Geigy Corporation
    Inventors: Alex Sele, Pier G. Ferrini, Georges Haas, Knut A. Jaeggi, Alberto Rossi
  • Patent number: 4192868
    Abstract: The invention relates to processes for the preparation of novel aryl-hexafuranosides of the formula ##STR1## in which R.sub.1 is lower alkyl or cycloalkyl and R.sub.2 is hydrogen, lower alkyl or acyl, or R.sub.1 and R.sub.2 together are alkylidene or cycloalkylidene, R.sub.3 is hydrogen, lower alkyl, lower alkenyl or aryl-lower alkyl, R.sub.5a and R.sub.6a independently of one another are hydrogen or lower alkyl, R.sub.5b and R.sub.6b independently of one another are hydrogen, hydroxyl, lower alkoxy or amino, or R.sub.5b and R.sub.6b together are a C--C bond, epoxy or lower alkylidene, and R.sub.6c is aryl, by methods known per se.These novel compounds have an anti-inflammatory and/or antinociceptive action.
    Type: Grant
    Filed: February 22, 1978
    Date of Patent: March 11, 1980
    Assignee: Ciba-Geigy Corporation
    Inventors: Jean M. J. Tronchet, Bruno Baehler, Alberto Rossi, Gerhard Baschang, Alex Sele
  • Patent number: 4177344
    Abstract: The invention relates to novel 1,6-anhydro-.beta.-D-hexopyranose derivatives of the formula I ##STR1## in which R.sub.2 is hydrogen, methyl or aromatic acyl, R.sub.3 and R.sub.4 are alkyl, alkenyl or aralkyl and one of the radicals R.sub.3 and R.sub.4 is also an aroyl radical and R.sub.4 can also be hydrogen, with the proviso that the radicals R.sub.3 and R.sub.4 together contain at least 3 carbon atoms and, if R.sub.4 is the benzyl radical, the radical R.sub.3 contains at least 2 carbon atoms, and, if one of the radicals R.sub.3 and R.sub.4 is an aroyl radical, R.sub.2 is hydrogen.These compounds especially the 1,6-anhydro-3,4-di-O-benzyl-.beta.-D-glucopyranose or the 1,6-anhydro-.beta.-D-glucopyranose, can be used as fibrinolytic agents and thrombolytic agents.
    Type: Grant
    Filed: September 16, 1977
    Date of Patent: December 4, 1979
    Assignee: Ciba-Geigy Corporation
    Inventors: Gerhard Baschang, Jaroslav Stanek, Alberto Rossi, Alex Sele
  • Patent number: 4112075
    Abstract: The invention relates to furanose-O-pyridylcarboxylic acid esters, such as the ethyl-2-O-methyl-3,5,6-tri-O-nicotinoyl-D-glucofuranoside, which have anti-inflammatory activity and are fibrinolysis activators. They can be used for the treatment of rheumatic and neuralgic complaints, and especially for the topical percutaneous treatment of localized inflammatory processes.
    Type: Grant
    Filed: September 9, 1976
    Date of Patent: September 5, 1978
    Assignee: Ciba-Geigy Corporation
    Inventors: Gerhard Baschang, Alex Sele, Jaroslav Stanek, Alberto Rossi