Patents by Inventor Alexander B. SMETANA
Alexander B. SMETANA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9650333Abstract: Disclosed is a chromatographic process complex for the refining of krill oil extract including desalting, removal of impurities such as trimethylamine oxide (TMAO), and the production of krill oil products including desalted krill oil extract, polar lipid products having polar lipid contents greater than 50 wt-% on a dry or solvent free basis, neutral lipid streams for biodiesel production and astaxanthin. The refinery includes a continuous desalting zone, a fixed bed polar lipid extraction zone to adsorb neutral lipids and astaxanthin to provide a polar lipid extract stream comprising solvent and polar lipids and being essentially free of neutral lipids and astaxanthin, and an astaxanthin separation zone to recover essentially pure astaxanthin and provide a neutral lipid stream. The enriched products of the krill oil refinery are essentially free of TMAO and salt and provide products which can be used as dietary supplements and as medicinal additives.Type: GrantFiled: December 16, 2016Date of Patent: May 16, 2017Assignee: OROCHEM Technologies, Inc.Inventors: Anil R. Oroskar, Asha A. Oroskar, Alexander B. Smetana, Slobodan Milasinovic, Xuejun Zang
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Patent number: 9650590Abstract: Disclosed is a chromatographic process complex for the refining of krill oil extract including desalting, removal of impurities such as trimethylamine oxide (TMAO), and the production of krill oil products including desalted krill oil extract, polar lipid products having polar lipid contents greater than 50 wt-% on a dry or solvent free basis, neutral lipid streams for biodiesel production and astaxanthin. The refinery includes a continuous desalting zone, a fixed bed polar lipid extraction zone to adsorb neutral lipids and astaxanthin to provide a polar lipid extract stream comprising solvent and polar lipids and being essentially free of neutral lipids and astaxanthin, and an astaxanthin separation zone to recover essentially pure astaxanthin and provide a neutral lipid stream. The enriched products of the krill oil refinery are essentially free of TMAO and salt and provide products which can be used as dietary supplements and as medicinal additives.Type: GrantFiled: December 16, 2016Date of Patent: May 16, 2017Assignee: OROCHEM Technologies, Inc.Inventors: Anil R. Oroskar, Asha A. Oroskar, Alexander B. Smetana, Slobodan Milasinovic, Xuejun Zang
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Publication number: 20170101373Abstract: Disclosed is a chromatographic process complex for the refining of krill oil extract including desalting, removal of impurities such as trimethylamine oxide (TMAO), and the production of krill oil products including desalted krill oil extract, polar lipid products having polar lipid contents greater than 50 wt-% on a dry or solvent free basis, neutral lipid streams for biodiesel production and astaxanthin. The refinery includes a continuous desalting zone, a fixed bed polar lipid extraction zone to adsorb neutral lipids and astaxanthin to provide a polar lipid extract stream comprising solvent and polar lipids and being essentially free of neutral lipids and astaxanthin, and an astaxanthin separation zone to recover essentially pure astaxanthin and provide a neutral lipid stream. The enriched products of the krill oil refinery are essentially free of TMAO and salt and provide products which can be used as dietary supplements and as medicinal additives.Type: ApplicationFiled: December 16, 2016Publication date: April 13, 2017Inventors: Anil R. Oroskar, Asha A. Oroskar, Alexander B. Smetana, Slobodan Milasinovic, Xuejun Zang
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Publication number: 20170101600Abstract: Disclosed is a chromatographic process complex for the refining of krill oil extract including desalting, removal of impurities such as trimethylamine oxide (TMAO), and the production of krill oil products including desalted krill oil extract, polar lipid products having polar lipid contents greater than 50 wt-% on a dry or solvent free basis, neutral lipid streams for biodiesel production and astaxanthin. The refinery includes a continuous desalting zone, a fixed bed polar lipid extraction zone to adsorb neutral lipids and astaxanthin to provide a polar lipid extract stream comprising solvent and polar lipids and being essentially free of neutral lipids and astaxanthin, and an astaxanthin separation zone to recover essentially pure astaxanthin and provide a neutral lipid stream. The enriched products of the krill oil refinery are essentially free of TMAO and salt and provide products which can be used as dietary supplements and as medicinal additives.Type: ApplicationFiled: December 16, 2016Publication date: April 13, 2017Inventors: Anil R. Oroskar, Asha A. Oroskar, Alexander B. Smetana, Slobodan Milasinovic, Xuejun Zang
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Patent number: 9556116Abstract: Disclosed is a chromatographic process complex for the refining of krill oil extract including desalting, removal of impurities such as trimethylamine oxide (TMAO), and the production of krill oil products including desalted krill oil extract, polar lipid products having polar lipid contents greater than 50 wt-% on a dry or solvent free basis, neutral lipid streams for biodiesel production and astaxanthin. The refinery includes a continuous desalting zone, a fixed bed polar lipid extraction zone to adsorb neutral lipids and astaxanthin to provide a polar lipid extract stream comprising solvent and polar lipids and being essentially free of neutral lipids and astaxanthin, and an astaxanthin separation zone to recover essentially pure astaxanthin and provide a neutral lipid stream. The enriched products of the krill oil refinery are essentially free of TMAO and salt and provide products which can be used as dietary supplements and as medicinal additives.Type: GrantFiled: February 11, 2015Date of Patent: January 31, 2017Assignee: OROCHEM Technologies, Inc.Inventors: Anil R. Oroskar, Asha A. Oroskar, Alexander B. Smetana, Slobodan Milasinovic, Xuejun Zang
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Publication number: 20160229781Abstract: Disclosed is a chromatographic process complex for the refining of krill oil extract including desalting, removal of impurities such as trimethylamine oxide (TMAO), and the production of krill oil products including desalted krill oil extract, polar lipid products having polar lipid contents greater than 50 wt-% on a dry or solvent free basis, neutral lipid streams for biodiesel production and astaxanthin. The refinery includes a continuous desalting zone, a fixed bed polar lipid extraction zone to adsorb neutral lipids and astaxanthin to provide a polar lipid extract stream comprising solvent and polar lipids and being essentially free of neutral lipids and astaxanthin, and an astaxanthin separation zone to recover essentially pure astaxanthin and provide a neutral lipid stream. The enriched products of the krill oil refinery are essentially free of TMAO and salt and provide products which can be used as dietary supplements and as medicinal additives.Type: ApplicationFiled: February 11, 2015Publication date: August 11, 2016Inventors: Anil R. OROSKAR, Asha A. Oroskar, Alexander B. Smetana, Slobodan Milasinovic, Xuejun Zang
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Publication number: 20120088694Abstract: Versatile, efficient cell assays which can be prepared with use of nanolithography and can be used to test nanomaterials, pharmaceuticals, toxins, and the like. For example, a method comprising: depositing at least one first composition comprising at least one cell adhesion material on at least one substrate to form a pattern which forms an interior space on the substrate within the pattern, depositing in the interior space on the substrate at least one second composition, different from the first, comprising at least one material adapted to affect or potentially affect cell function. Tip-based deposition and direct-write methods can be used for deposition at nanoscale and sub-cellular resolutions. Nanoscopic and atomic force microscope tips can be used. Multiplexing can be carried out.Type: ApplicationFiled: October 3, 2011Publication date: April 12, 2012Inventors: Saju Nettikadan, John Michael Collins, Alexander B. Smetana, Paul Leon Stiles
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Publication number: 20110277193Abstract: Multiplexed printing and sensors for biological applications. Sensors can be made with high sensitivity and by high throughput methods. Multiple capture molecules can be applied to the same or different sensor elements such as cantilevers. The sensor element can be a microcantilever. Direct write lithography from nanoscopic tips can be used to make the sensor. Proteins and hydrogels can be printed. Specific binding can be detected.Type: ApplicationFiled: April 20, 2011Publication date: November 10, 2011Inventors: Alexander B. SMETANA, Saju R. Nettikadan