Patents by Inventor Alexander Domling

Alexander Domling has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Arginase inhibitors
    Patent number: 11845767
    Abstract: The present invention relates to novel arginase inhibitors of formula (I). These novel compounds are useful in the treatment of diseases that are associated with arginase activity, such as asthma, allergic rhinitis and COPD (chronic obstructive pulmonary disease).
    Type: Grant
    Filed: June 15, 2020
    Date of Patent: December 19, 2023
    Assignee: Rijksuniversiteit Groningen
    Inventors: Santosh Kurhade, Alexander Dömling
  • NOVEL ARGINASE INHIBITORS
    Publication number: 20220227791
    Abstract: The present invention relates to novel arginase inhibitors of formula (I). These novel compounds are useful in the treatment of diseases that are associated with arginase activity, such as asthma, allergic rhinitis and COPD (chronic obstructive pulmonary disease).
    Type: Application
    Filed: June 15, 2020
    Publication date: July 21, 2022
    Inventors: Santosh Kurhade, Alexander Dömling
  • INHIBITORS OF THE PD-1/PD-L1 PROTEIN/PROTEIN INTERACTION
    Publication number: 20190016681
    Abstract: The present invention provides novel compounds of formula (I) that are useful as inhibitors of the PD-1/PD-L1 protein/protein interaction.
    Type: Application
    Filed: January 9, 2017
    Publication date: January 17, 2019
    Applicant: Rijksuniversiteit Groningen
    Inventor: Alexander DÖMLING
  • Tubulysin analogues
    Patent number: 7816377
    Abstract: The invention relates to tubulysin derivatives of general formula (II), said derivatives having a cytostatic effect.
    Type: Grant
    Filed: July 9, 2003
    Date of Patent: October 19, 2010
    Assignee: R&D-Biopharmaceuticals GmbH
    Inventors: Alexander Dömling, Bernd Henkel, Barbara Beck, Katrin Illgen, Sukumar Sakamuri, Sanjay Menon
  • Tubulysin conjugates
    Patent number: 7776814
    Abstract: The invention relates to novel tubulysin conjugates (e.g. of tubulysin A) and the use thereof in the treatment of cancer diseases.
    Type: Grant
    Filed: July 9, 2003
    Date of Patent: August 17, 2010
    Assignee: R&D-Biopharmaceuticals GmbH
    Inventors: Alexander Dömling, Lutz Weber
  • Tubulysin conjugates
    Publication number: 20050249740
    Abstract: The invention relates to novel tubulysin conjugates (e.g. of tubulysin A) and the use thereof in the treatment of cancer diseases.
    Type: Application
    Filed: July 9, 2003
    Publication date: November 10, 2005
    Inventors: Alexander Domling, Lutz Weber
  • Novel tubulysin analogues
    Publication number: 20050239713
    Abstract: The invention relates to tubulysin derivatives of general formula (II), said derivatives having a cytostatic effect.
    Type: Application
    Filed: July 9, 2003
    Publication date: October 27, 2005
    Applicant: R&D-Biopharmaceuticals Am
    Inventors: Alexander Domling, Bernd Henkel, Barbara Beck, Katrin Illgen, Sukumar Sakamuri, Sanjay Menon
  • Utilization of inhibitors of rho-kinases for stimulating nerve growth, inhibiting scar tissue formation and/or reducing a secondary lesion
    Publication number: 20050096253
    Abstract: The present invention relates to the use of inhibitors of rho-kinases in the in vivo stimulation of nerve growth, in the in vivo inhibition of scar tissue formation and/or in the in vivo reduction of secondary damage.
    Type: Application
    Filed: October 31, 2002
    Publication date: May 5, 2005
    Inventors: Philippe Monnier, Bernd Stahl, Bernhard Muller, Alexander Domling, Werner Schiebler
  • Butenolide and pentenolide derivatives as kinase inhibitors
    Publication number: 20040102488
    Abstract: The present invention relates to new compounds of the general formula (I), 1
    Type: Application
    Filed: July 15, 2003
    Publication date: May 27, 2004
    Inventors: Barbara Beck, Alexander Domling