Patents by Inventor Alexander Dorrestein
Alexander Dorrestein has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11980645Abstract: Compositions and methods of use for modulating bile acids, including phenylalanocholic acid, tyrosocholic acid and leucocholic acid, to treat diseases, such as inflammatory bowel disease. In embodiments, the invention provides pharmaceutical compositions that modulate levels of a bile acid conjugate in a subject. In embodiments, the invention provides pharmaceutical compositions that modulate levels of a bile acid conjugate in a particular organ or bodily region of the subject.Type: GrantFiled: January 22, 2020Date of Patent: May 14, 2024Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIAInventors: Pieter Dorrestein, Alexey Melnik, Alexander Aksenov, Robert Quinn
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Publication number: 20230280548Abstract: A fiber optic cassette includes a body defining a front and an opposite rear. A cable entry location is defined on the body for a cable to enter the cassette, wherein a plurality of optical fibers from the cable extend into the cassette and form terminations at non-conventional connectors adjacent the front of the body. A flexible substrate is positioned between the cable entry location and the non-conventional connectors adjacent the front of the body, the flexible substrate rigidly supporting the plurality of optical fibers. Each of the non-conventional connectors adjacent the front of the body includes a ferrule, a ferrule hub supporting the ferrule, and a split sleeve surrounding the ferrule.Type: ApplicationFiled: February 27, 2023Publication date: September 7, 2023Applicants: CommScope Technologies LLC, CommScope Asia Holdings B.V., CommScope Connectivity Spain, S.L., CommScope Connectivity UK LimitedInventors: David P. MURRAY, Ton BOLHAAR, Paul SCHNEIDER, Rafael MATEO, Luis COBACHO, Michael WENTWORTH, Steven J. BRANDT, Marcellus PJ BUIJS, Alexander DORRESTEIN, Jan Willem RIETVELD
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Publication number: 20230266552Abstract: A fiber optic cassette includes a body defining a front and an opposite rear. A cable entry location, such as a multi-fiber connector, is defined on the body for a cable to enter the cassette, wherein a plurality of optical fibers from the cable extend into the cassette and form terminations at one or more single or multi-fiber connectors adjacent the front of the body. A flexible substrate is positioned between the cable entry location and the connectors adjacent the front of the body, the flexible substrate rigidly supporting the plurality of optical fibers. Each of the connectors adjacent the front of the body includes a ferrule. Dark fibers can be provided if not all fiber locations are used in the multi-fiber connectors. Multiple flexible substrates can be used with one or more multi-fiber connectors.Type: ApplicationFiled: February 6, 2023Publication date: August 24, 2023Inventors: Paul Schneider, Alexander Dorrestein, James Joseph Eberle, JR.
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Publication number: 20230128196Abstract: A double flexible optical circuit includes: a flexible substrate supporting a plurality of optical fibers; a first connector terminating the optical fibers at a first end of the double flexible optical circuit; and a second connector terminating the optical fibers at a second end of the double flexible optical circuit. Each of the optical fibers is positioned in one of a plurality of separate extensions formed by the flexible substrate as the optical fibers extend from the first connector to the second connector. The first and second connectors are configured to be tested when the first and second connectors are connected through the double flexible optical circuit. The double flexible optical circuit is configured to be divided in half once the testing is complete to form two separate flexible optical circuits.Type: ApplicationFiled: September 30, 2022Publication date: April 27, 2023Applicants: CommScope Connectivity UK Limited, CommScope Connectivity Spain, S.L., CommScope Asia Holdings B.V., CommScope Technologies LLCInventors: David P. MURRAY, Ton BOLHAAR, Paul SCHNEIDER, Rafael MATEO, Luis COBACHO, Michael WENTWORTH, Steven J. BRANDT, Marcellus PJ BUIJS, Alexander DORRESTEIN, Jan Willem RIETVELD
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Patent number: 11592628Abstract: A fiber optic cassette includes a body defining a front and an opposite rear. A cable entry location is defined on the body for a cable to enter the cassette, wherein a plurality of optical fibers from the cable extend into the cassette and form terminations at non-conventional connectors adjacent the front of the body. A flexible substrate is positioned between the cable entry location and the non-conventional connectors adjacent the front of the body, the flexible substrate rigidly supporting the plurality of optical fibers. Each of the non-conventional connectors adjacent the front of the body includes a ferrule, a ferrule hub supporting the ferrule, and a split sleeve surrounding the ferrule.Type: GrantFiled: June 10, 2021Date of Patent: February 28, 2023Assignees: CommScope Technologies LLC, CommScope Asia Holdings B.V., CommScope Connectivity Spain, S.L., CommScope Connectivity UK LimitedInventors: David P. Murray, Ton Bolhaar, Paul Schneider, Rafael Mateo, Luis Cobacho, Michael Wentworth, Steven J. Brandt, Marcellus P J Buijs, Alexander Dorrestein, Jan Willem Rietveld
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Patent number: 11579381Abstract: A transceiver assembly for mounting on a mother board, said transceiver assembly comprising: (a) a frame defining a first plane configured for mounting parallel to said motherboard, said frame defining a plurality of slots perpendicular to said first plane; and (b) one or more opto-electric cards, each of said one or more opto-electric cards disposed in one of said plurality of slots and comprising at least, (i) a substrate having a first edge parallel to said first plane when said opto-electric card is mounted in said slot, (ii) an electrical interface along said first edge, (iii) and an interposer electrically connected to said electrical interface and comprising at least one optical component operatively connected to said electrical interface, and (iv) at least one optical fiber extending freely from said interposer.Type: GrantFiled: October 28, 2020Date of Patent: February 14, 2023Assignee: TE CONNECTIVITY NEDERLAND BVInventors: Jacobus Nicolaas Tuin, Sander Johannes Floris, Rutger Wilhelmus Smink, Alexander Dorrestein
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Patent number: 11573389Abstract: A fiber optic cassette includes a body defining a front and an opposite rear. A cable entry location, such as a multi-fiber connector, is defined on the body for a cable to enter the cassette, wherein a plurality of optical fibers from the cable extend into the cassette and form terminations at one or more single or multi-fiber connectors adjacent the front of the body. A flexible substrate is positioned between the cable entry location and the connectors adjacent the front of the body, the flexible substrate rigidly supporting the plurality of optical fibers. Each of the connectors adjacent the front of the body includes a ferrule. Dark fibers can be provided if not all fiber locations are used in the multi-fiber connectors. Multiple flexible substrates can be used with one or more multi-fiber connectors.Type: GrantFiled: March 9, 2021Date of Patent: February 7, 2023Assignees: CommScope Asia Holdings B.V., CommScope Techologies LLCInventors: Paul Schneider, Alexander Dorrestein, James Joseph Eberle, Jr.
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Patent number: 11467347Abstract: A double flexible optical circuit includes: a flexible substrate supporting a plurality of optical fibers; a first connector terminating the optical fibers at a first end of the double flexible optical circuit; and a second connector terminating the optical fibers at a second end of the double flexible optical circuit. Each of the optical fibers is positioned in one of a plurality of separate extensions formed by the flexible substrate as the optical fibers extend from the first connector to the second connector. The first and second connectors are configured to be tested when the first and second connectors are connected through the double flexible optical circuit. The double flexible optical circuit is configured to be divided in half once the testing is complete to form two separate flexible optical circuits.Type: GrantFiled: July 17, 2020Date of Patent: October 11, 2022Assignees: CommScope Connectivity UK Limited, CommScope Connectivity Spain, S.L., CommScope Asia Holdings B.V., CommScope Technologies LLCInventors: David P. Murray, Ton Bolhaar, Paul Schneider, Rafael Mateo, Luis Cobacho, Michael Wentworth, Steven J. Brandt, Marcellus P J Buijs, Alexander Dorrestein, Jan Willem Rietveld
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Publication number: 20210302669Abstract: A fiber optic cassette includes a body defining a front and an opposite rear. A cable entry location is defined on the body for a cable to enter the cassette, wherein a plurality of optical fibers from the cable extend into the cassette and form terminations at non-conventional connectors adjacent the front of the body. A flexible substrate is positioned between the cable entry location and the non-conventional connectors adjacent the front of the body, the flexible substrate rigidly supporting the plurality of optical fibers. Each of the non-conventional connectors adjacent the front of the body includes a ferrule, a ferrule hub supporting the ferrule, and a split sleeve surrounding the ferrule.Type: ApplicationFiled: June 10, 2021Publication date: September 30, 2021Applicants: CommScope Technologies LLC, CommScope Asia Holdings B.V., CommScope Connectivity Spain, S.L., CommScope Connectivity UK LimitedInventors: David P. MURRAY, Ton BOLHAAR, Paul SCHNEIDER, Rafael MATEO, Luis COBACHO, Michael WENTWORTH, Steven J. BRANDT, Marcellus PJ BUIJS, Alexander DORRESTEIN, Jan Willem RIETVELD
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Publication number: 20210263252Abstract: A fiber optic cassette includes a body defining a front and an opposite rear. A cable entry location, such as a multi-fiber connector, is defined on the body for a cable to enter the cassette, wherein a plurality of optical fibers from the cable extend into the cassette and form terminations at one or more single or multi-fiber connectors adjacent the front of the body. A flexible substrate is positioned between the cable entry location and the connectors adjacent the front of the body, the flexible substrate rigidly supporting the plurality of optical fibers. Each of the connectors adjacent the front of the body includes a ferrule. Dark fibers can be provided if not all fiber locations are used in the multi-fiber connectors. Multiple flexible substrates can be used with one or more multi-fiber connectors.Type: ApplicationFiled: March 9, 2021Publication date: August 26, 2021Inventors: Paul Schneider, Alexander Dorrestein, James Joseph Eberle, JR.
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Patent number: 11036012Abstract: A fiber optic cassette includes a body defining a front and an opposite rear. A cable entry location is defined on the body for a cable to enter the cassette, wherein a plurality of optical fibers from the cable extend into the cassette and form terminations at non-conventional connectors adjacent the front of the body. A flexible substrate is positioned between the cable entry location and the non-conventional connectors adjacent the front of the body, the flexible substrate rigidly supporting the plurality of optical fibers. Each of the non-conventional connectors adjacent the front of the body includes a ferrule, a ferrule hub supporting the ferrule, and a split sleeve surrounding the ferrule.Type: GrantFiled: July 29, 2020Date of Patent: June 15, 2021Assignees: CommScope Technologies LLC, CommScope Asia Holdings B.V., CommScope Connectivity Spain, S.L., CommScope Connectivity UK LimitedInventors: David P. Murray, Ton Bolhaar, Paul Schneider, Rafael Mateo, Luis Cobacho, Michael Wentworth, Steven J. Brandt, Marcellus PJ Buijs, Alexander Dorrestein, Jan Willem Rietveld
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Patent number: 10955633Abstract: A fiber optic cassette includes a body defining a front and an opposite rear. A cable entry location, such as a multi-fiber connector, is defined on the body for a cable to enter the cassette, wherein a plurality of optical fibers from the cable extend into the cassette and form terminations at one or more single or multi-fiber connectors adjacent the front of the body. A flexible substrate is positioned between the cable entry location and the connectors adjacent the front of the body, the flexible substrate rigidly supporting the plurality of optical fibers. Each of the connectors adjacent the front of the body includes a ferrule. Dark fibers can be provided if not all fiber locations are used in the multi-fiber connectors. Multiple flexible substrates can be used with one or more multi-fiber connectors.Type: GrantFiled: June 5, 2019Date of Patent: March 23, 2021Assignees: CommScope Asia Holdings B.V., CommScope Techologies LLCInventors: Paul Schneider, Alexander Dorrestein, James Joseph Eberle, Jr.
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Publication number: 20210072466Abstract: A transceiver assembly for mounting on a mother board, said transceiver assembly comprising: (a) a frame defining a first plane configured for mounting parallel to said motherboard, said frame defining a plurality of slots perpendicular to said first plane; and (b) one or more opto-electric cards, each of said one or more opto-electric cards disposed in one of said plurality of slots and comprising at least, (i) a substrate having a first edge parallel to said first plane when said opto-electric card is mounted in said slot, (ii) an electrical interface along said first edge, (iii) and an interposer electrically connected to said electrical interface and comprising at least one optical component operatively connected to said electrical interface, and (iv) at least one optical fiber extending freely from said interposer.Type: ApplicationFiled: October 28, 2020Publication date: March 11, 2021Inventors: Jacobus Nicolaas Tuin, Sander Johannes Floris, Rutger Wilhelmus Smink, Alexander Dorrestein
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Publication number: 20210011228Abstract: A fiber optic cassette includes a body defining a front and an opposite rear. A cable entry location is defined on the body for a cable to enter the cassette, wherein a plurality of optical fibers from the cable extend into the cassette and form terminations at non-conventional connectors adjacent the front of the body. A flexible substrate is positioned between the cable entry location and the non-conventional connectors adjacent the front of the body, the flexible substrate rigidly supporting the plurality of optical fibers. Each of the non-conventional connectors adjacent the front of the body includes a ferrule, a ferrule hub supporting the ferrule, and a split sleeve surrounding the ferrule.Type: ApplicationFiled: July 29, 2020Publication date: January 14, 2021Applicants: CommScope Technologies LLC, CommScope Asia Holdings B.V., CommScope Connectivity Spain, S.L., CommScope Connectivity UK LimitedInventors: David P. MURRAY, Ton BOLHAAR, Paul SCHNEIDER, Rafael MATEO, Luis COBACHO, Michael WENTWORTH, Steven J. BRANDT, Marcellus PJ BUIJS, Alexander DORRESTEIN, Jan Willem RIETVELD
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Publication number: 20200400901Abstract: An optical subassembly comprising: (a) an interposer having first and second opposing sides and defining an alignment aperture extending from said first opposing side to said second opposing side, said interposer defining traces having contacts; (b) a fiber having a first optical axis, said fiber being held such that first optical axis is positioned essentially orthogonal to said first and second opposing sides; (c) at least one optical component mounted to said second opposing side and being electrically connected to at least a portion of said contacts, said at least one optical component having a second optical axis coincident with said first optical axis; and (d) a circuit board configured to receive said interposer such that said interposer is essentially orthogonal to said circuit board and said first optical axis is essentially parallel to said circuit board, said circuit board being electrically connected to at least a portion of said contacts.Type: ApplicationFiled: June 24, 2019Publication date: December 24, 2020Inventors: Alexander Dorrestein, Jacobus Nicolaas Tuin, Rutger Wilhelmus Smink
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Publication number: 20200400899Abstract: A transceiver assembly for mounting on a mother board, said transceiver assembly comprising: (a) a frame defining a first plane configured for mounting parallel to said motherboard, said frame defining a plurality of slots perpendicular to said first plane; and (b) one or more opto-electric cards, each of said one or more opto-electric cards disposed in one of said plurality of slots and comprising at least, (i) a substrate having a first edge parallel to said first plane when said opto-electric card is mounted in said slot, (ii) an electrical interface along said first edge, (iii) and an interposer electrically connected to said electrical interface and comprising at least one optical component operatively connected to said electrical interface, and (iv) at least one optical fiber extending freely from said interposer.Type: ApplicationFiled: June 24, 2019Publication date: December 24, 2020Inventors: Jacobus Nicolaas Tuin, Sander Johannes Floris, Rutger Wilhelmus Smink, Alexander Dorrestein
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Patent number: 10852489Abstract: A transceiver assembly for mounting on a mother board, said transceiver assembly comprising: (a) a frame defining a first plane configured for mounting parallel to said motherboard, said frame defining a plurality of slots perpendicular to said first plane; and (b) one or more opto-electric cards, each of said one or more opto-electric cards disposed in one of said plurality of slots and comprising at least, (i) a substrate having a first edge parallel to said first plane when said opto-electric card is mounted in said slot, (ii) an electrical interface along said first edge, (iii) and an interposer electrically connected to said electrical interface and comprising at least one optical component operatively connected to said electrical interface, and (iv) at least one optical fiber extending freely from said interposer.Type: GrantFiled: June 24, 2019Date of Patent: December 1, 2020Inventors: Jacobus Nicolaas Tuin, Sander Johannes Floris, Rutger Wilhelmus Smink, Alexander Dorrestein
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Publication number: 20200348471Abstract: A double flexible optical circuit includes: a flexible substrate supporting a plurality of optical fibers; a first connector terminating the optical fibers at a first end of the double flexible optical circuit; and a second connector terminating the optical fibers at a second end of the double flexible optical circuit. Each of the optical fibers is positioned in one of a plurality of separate extensions formed by the flexible substrate as the optical fibers extend from the first connector to the second connector. The first and second connectors are configured to be tested when the first and second connectors are connected through the double flexible optical circuit. The double flexible optical circuit is configured to be divided in half once the testing is complete to form two separate flexible optical circuits.Type: ApplicationFiled: July 17, 2020Publication date: November 5, 2020Inventors: David P. MURRAY, Ton BOLHAAR, Paul SCHNEIDER, Rafael MATEO, Luis COBACHO, Michael WENTWORTH, Steven J. BRANDT, Marcellus PJ BUIJS, Alexander DORRESTEIN, Jan Willem RIETVELD
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Patent number: 10754096Abstract: A double flexible optical circuit includes: a flexible substrate supporting a plurality of optical fibers; a first connector terminating the optical fibers at a first end of the double flexible optical circuit; and a second connector terminating the optical fibers at a second end of the double flexible optical circuit. Each of the optical fibers is positioned in one of a plurality of separate extensions formed by the flexible substrate as the optical fibers extend from the first connector to the second connector. The first and second connectors are configured to be tested when the first and second connectors are connected through the double flexible optical circuit. The double flexible optical circuit is configured to be divided in half once the testing is complete to form two separate flexible optical circuits.Type: GrantFiled: August 17, 2017Date of Patent: August 25, 2020Assignees: CommScope Connectivity UK Limited, CommScope Connectivity Spain, S.L., CommScope Asia Holdings B.V., CommScope Technologies LLCInventors: David Patrick Murray, Ton Bolhaar, Paul Schneider, Rafael Mateo, Luis Cobacho, Michael Wentworth, Steven J. Brandt, Marcellus P J Buijs, Alexander Dorrestein, Jan Willem Rietveld
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Patent number: 10739534Abstract: A fiber optic cassette includes a body defining a front and an opposite rear. A cable entry location is defined on the body for a cable to enter the cassette, wherein a plurality of optical fibers from the cable extend into the cassette and form terminations at non-conventional connectors adjacent the front of the body. A flexible substrate is positioned between the cable entry location and the non-conventional connectors adjacent the front of the body, the flexible substrate rigidly supporting the plurality of optical fibers. Each of the non-conventional connectors adjacent the front of the body includes a ferrule, a ferrule hub supporting the ferrule, and a split sleeve surrounding the ferrule.Type: GrantFiled: May 20, 2019Date of Patent: August 11, 2020Assignees: CommScope Technologies LLC, CommScope Asia Holdings B.V., CommScope Connectivity Spain, S.L., CommScope Connectivity UK LimitedInventors: David P. Murray, Ton Bolhaar, Paul Schneider, Rafael Mateo, Luis Cobacho, Michael Wentworth, Steven J. Brandt, Marcellus P J Buijs, Alexander Dorrestein, Jan Willem Rietveld