Abstract: A system and method of acquiring an image at a magnetic resonance imaging (MRI) system is provided. Accordingly, an analog signal based on a pulse sequence and a first gain is obtained. The analog signal is converted into a digitized signal. A potential quantization error is detected in the digitized signal based on a boundary. When the detection is affirmative, a replacement analog signal based on the pulse sequence is received. At least one portion of the replacement analog signal can be based on an adjusted gain. The adjusted gain is a factor of the first gain. The replacement analog signal is digitized into a replacement digitized signal. At least one portion of the replacement digitized signal corresponding to the at least one portion of the replacement analog signal is adjusted based on a reversal of the factor.

Abstract: Some implementations provide a method for safe operation of a magnetic resonance imaging (MRI) system, the method including: determining, at least in part by using a sensor device, location information that indicates a location of an MR-incompatible object relative to the MRI system, the MRI system generating a polarizing magnetic field for imaging a subject; based on the determined location information, determining, by a control unit associated with the MRI system, that the MR-incompatible object poses an operational hazard to the MRI system; and in response to determining that the MR-incompatible object poses an operational hazard to the MRI system, reducing, by the control unit, a strength of the polarizing magnetic field.

Abstract: A system and method of acquiring an image at a magnetic resonance imaging (MRI) system is provided. Accordingly, an analog signal based on a pulse sequence and a first gain is obtained. The analog signal is converted into a digitized signal. A potential quantization error is detected in the digitized signal based on a boundary. When the detection is affirmative, a replacement analog signal based on the pulse sequence is received. At least one portion of the replacement analog signal can be based on an adjusted gain. The adjusted gain is a factor of the first gain. The replacement analog signal is digitized into a replacement digitized signal. At least one portion of the replacement digitized signal corresponding to the at least one portion of the replacement analog signal is adjusted based on a reversal of the factor.

Abstract: A delta-relaxation magnetic resonance imaging (DREMR) system is provided. The system includes a main field magnet and field shifting coils. A main magnetic field with a strength B0 can be generated using the main filed magnet and the strength B0 of the main magnetic field can be varied through the use of the field-shifting coils. The DREMR system can be used to perform signal acquisition based on a pulse sequence for acquiring at least one of T2*-weighted signals imaging; MR spectroscopy signals; saturation imaging signals and MR signals for fingerprinting. The MR signal acquisition can be augmented by varying the strength B0 of the main magnetic field for at least a portion of the pulse sequence used to acquire the MR signal.

Abstract: Described here are systems and methods for mitigating or otherwise removing the effects of short-term magnetic field instabilities caused by oscillations of the cold head in a cryogen-free magnet system used for magnetic resonance systems, such as magnetic resonance imaging (“MRI”) systems, nuclear magnetic resonance (“NMR”) systems, or the like.

Abstract: Systems and methods for magnetic field-dependent relaxometry using magnetic resonance imaging (“MRI”] are provided. Relaxation parameters, including longitudinal relaxation time (“T1”) and transverse relaxation time (“T2”), are estimated from magnetic resonance signal data acquired at multiple different magnetic field strengths using the same MRI system. By measuring these relaxation parameters as a function of magnetic field strength, T1 dispersion data, T2 dispersion data, or both, are generated. Based on this dispersion data, quantitative physiological parameters can be estimated. As one example, iron content can be estimated from T2 dispersion data.

Abstract: A method of configuring a conducting grid of elements interconnected at intersecting nodes by switches is described.

Abstract: A medical navigation system is provided for registering a patient for a medical procedure with the medical navigation system using fiducial markers. The fiducial markers are placed on the patient prior to a 3D scan and the fiducial markers each have a target for use with a tracking system. The medical navigation system comprises a 3D scanner, a tracking system, a display, and a controller electrically coupled to the 3D scanner, the tracking system, and the display. The controller has a processor coupled to a memory.

Abstract: Optionally adjustable head coil system and methods for enhancing and/or optimizing magnetic resonance imaging, involving a housing, the housing having at least one portion, the at least one portion having a lower portion, an upper portion, and opposing side portions, each at least one portion optionally in movable relation to any other portion for facilitating adjustability, each at least one portion configured to accommodate at least one radio-frequency coil, and the upper and lower portions each optionally configured to overlap and engage the opposing side portions for facilitating decoupling the at least one radio-frequency coil, and a tongue portion optionally in movable relation to any other portion for facilitating adjustability, engageable with the lower portion, and fixably couple-able with a transporter.

Abstract: A delta-relaxation magnetic resonance imaging (DREMR) system is provided. The system includes a main field magnet and field shifting coils. A main magnetic field with a strength B0 can be generated using the main filed magnet and the strength B0 of the main magnetic field can be varied through the use of the field-shifting coils. The DREMR system can be used to perform signal acquisition based on a pulse sequence for acquiring at least one of T2*-weighted signals imaging; MR spectroscopy signals; saturation imaging signals and MR signals for fingerprinting. The MR signal acquisition can be augmented by varying the strength B0 of the main magnetic field for at least a portion of the pulse sequence used to acquire the MR signal.

Abstract: Methods for correcting a non-uniform power response of a radiofrequency (“RF”) transmit coil used in magnetic resonance imaging (“MRI”) are described. Transmit power response data for an RF transmit coil are processed to compute RF amplitude scaling factors for the RF transmit coil as a function of transmit frequency offset. The RF amplitude scaling factors can be used to correct transmitted RF power, and thus flip angle, to be more uniform over a range of transmit frequency offsets, as may be encountered when imaging with lower field MRI systems or MRI systems with high strength or asymmetric gradients.

Abstract: A method of generating adjusted image data to compensate for modality-induced distortion includes, at a processor: receiving a three-dimensional image captured with a first imaging modality and including (i) distorted surface image data depicting a surface of an object and (ii) distorted volume image data depicting a volume of the object; extracting the distorted surface image data from the three-dimensional image; receiving reference surface image data captured with a second imaging modality and depicting the surface of the object; determining a surface transformation for registering the distorted surface image data with the reference surface image data; determining a volume transformation informed by the surface transformation; generating an adjusted three-dimensional image by applying the volume transformation to the three-dimensional image; and storing the adjusted three-dimensional image in the memory.

Abstract: A method of imaging an implant device in a computing device is provided. The computing device includes a processor interconnected with a memory and a display. The method includes, at the processor: obtaining a first magnetic resonance (MR) image of a patient tissue, the first MR image containing a first magnetic field strength indicator; responsive to the implant device being inserted in the patient tissue, obtaining a second MR image of the patient tissue, the second MR image containing a second magnetic field strength indicator smaller than the first magnetic field strength indicator; registering the second MR image with the first MR image; generating a composite image from the first MR image and the second MR image; and presenting the composite image on the display.

Abstract: Some implementations provide a method for safe operation of a magnetic resonance imaging (MRI) system, the method including: determining, at least in part by using a sensor device, location information that indicates a location of an MR-incompatible object relative to the MRI system, the MRI system generating a polarizing magnetic field for imaging a subject; based on the determined location information, determining, by a control unit associated with the MRI system, that the MR-incompatible object poses an operational hazard to the MRI system; and in response to determining that the MR-incompatible object poses an operational hazard to the MRI system, reducing, by the control unit, a strength of the polarizing magnetic field.

Abstract: A medical navigation system is provided for registering a patient for a medical procedure with the medical navigation system using fiducial markers. The fiducial markers are placed on the patient prior to a 3D scan and the fiducial markers each have a target for use with a tracking system. The medical navigation system comprises a 3D scanner, a tracking system, a display, and a controller electrically coupled to the 3D scanner, the tracking system, and the display. The controller has a processor coupled to a memory.

Abstract: A method of maintaining patient registration in surgical navigation includes: obtaining a patient position in a tracking system frame of reference, based on a fiducial marker array affixed in a first position relative to the patient; receiving an initial surface scan depicting the patient and the fiducial array; responsive to receiving an intraoperative image depicting the patient: obtaining a position, in the tracking system frame of reference, of the fiducial array affixed in a second position relative to the patient; receiving a secondary surface scan depicting the patient and the fiducial array; detecting a deviation in a position of the fiducial marker array relative to the patient between the initial and secondary surface scans; and applying the deviation to the position of the patient to generate an updated position of the patient in the tracking system frame of reference, based on the fiducial array affixed in the second position.

Abstract: A medical imaging system for illuminating tissue samples using three-dimensional structured illumination microscopy is port-based surgery is provided. The system comprises: an image sensor; a mirror device; zoom optics; a light modulator; a processor; and collimating optics configured to convey one or more images from the modulator to the mirror, the mirror configured to convey the images to the zoom optics, the zoom optics configured: to convey the image(s) from the mirror to a tissue sample; and convey one or more resulting images, formed by the image(s) illuminating the sample, back to the mirror, which conveys the resulting image(s) from the zoom optics to the image sensor, and, the processor configured to control the modulator to form the image(s), the image(s) including at least one pattern selected to interact with the sample to generate different depth information in each of resulting image(s).

Abstract: Some implementations provide a system that includes: a main magnet including a bore and configured to generate a substantially uniform magnetic field in the bore; one or more gradient coils configured to perturb the substantially uniform magnetic field in the bore, wherein perturbing the substantially uniform magnetic field results in a first varying magnetic field outside of the bore; and one or more shielding units located outside of the bore and configured to generate a second varying magnetic field con figured to attenuate the first varying magnetic field outside of the bore.

Abstract: A method of generating adjusted image data to compensate for modality-induced distortion includes, at a processor: receiving a three-dimensional image captured with a first imaging modality and including (i) distorted surface image data depicting a surface of an object and (ii) distorted volume image data depicting a volume of the object; extracting the distorted surface image data from the three-dimensional image; receiving reference surface image data captured with a second imaging modality and depicting the surface of the object; determining a surface transformation for registering the distorted surface image data with the reference surface image data; determining a volume transformation informed by the surface transformation; generating an adjusted three-dimensional image by applying the volume transformation to the three-dimensional image; and storing the adjusted three-dimensional image in the memory.

Abstract: A method of correcting warping of an acquired image in an MRI system, caused by non-linearities in gradient field profiles of gradient coils is set forth, comprising a) constructing a computer model representing conducting pathways for each gradient coil in said MRI system; b) calculating a predicted magnetic field at each point in space for each said gradient coil in said model; c) measuring actual magnetic field at each point in space for each said gradient coil in said MRI system; d) verifying accuracy of said model by comparing said predicted magnetic field to said actual magnetic field at each said point in space and in the event said model is not accurate then repeating a)-d), and in the event said model is accurate then; constructing a distortion map for mapping coordinates in real space to coordinates in warped space of said acquired image based on deviations of said predicted magnetic field from linearity; and unwarping said warping of the acquired image using said distortion map.